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  • 1
    Electronic Resource
    Electronic Resource
    MR arthrography of the shoulder: comparison of low-field (0.2 T) vs high-field (1.5 T) imaging (2000)
    Springer
    European radiology 10 (2000), S. 989-996 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Shoulder – MR arthrography – Field strength – Rotator cuff – Glenoid labrum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The objective of this study was to compare the image quality, sensitivity, specificity, and diagnostic accuracy of an open low-field MR system (0.2 T) with a standard high-field MR system (1.5 T) after arthrography of the shoulder. Thirty-eight patients either with suspected chronic instability (n = 12) or rotator cuff abnormalities (n = 26) were examined. Intra-articular injection of diluted Gd-DTPA was followed in randomized order either first by imaging on an open 0.2-T system or on a 1.5-T system. The image material was evaluated independently by two radiologists in a blinded fashion with respect to overall image quality and the detection of rotator cuff as well as capsular and labral abnormalities. Surgical correlation was available in 27 (71 %) of 38 patients. For both systems, sensitivity and specificity for rotator cuff tears were 100 % each, and for labrum pathologies, these values were 100 and 93 %, respectively. The agreement for detection of labral pathologies between low-field and high-field examinations was good (ϰ = 0.69, ϰ = 0.61). For the detection of full-thickness tears of the rotator cuff, the agreement between the low-field and high-field MR examinations was very good and significant (ϰ = 0.94, ϰ = 1, p 〈 0.001). Overall image quality was rated good in 17 (45 %) and fair in 21 (55 %) of 38 cases on the 0.2-T MR system, and good in 32 (84 %) and fair in 6 (16 %) of 38 cases on the 1.5-T system. Motion artifacts were considered low in 24 (63 %) and moderate in 14 (37 %) of 38 cases for the 0.2-T system and low in 34 (89 %) and moderate in 4 (11 %) for 1.5-T system. Based on our results, low-field MR compares favorably to high-field MR in the detection of major abnormalities of the glenohumeral joint, at least when MR arthrography is used. Disadvantages are the duration of the examination and thus the risk of reduced image quality caused by motion artifacts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300051050
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  • 2
    Electronic Resource
    Electronic Resource
    Injuries of the lateral collateral ligaments of the ankle: assessment with MR imaging (1999)
    Springer
    European radiology 9 (1999), S. 519-524 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Ankle ; Ankle sprain ; Lateral collateral ligaments ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The aim of this study was to evaluate the ability of MRI to display injuries of the lateral collateral ligamentous complex in patients with an acute ankle distorsion trauma. The MR examinations of 36 patients with ankle pain after ankle distorsion were evaluated retrospectively without knowledge of clinical history, outcome and/or operative findings. The examinations were performed on a 1.5-T whole-body imager using a flexible surface coil. The signs for ligamentous abnormality were as follows: complete or partial discontinuity, increased signal within, and irregularity and waviness of the ligament. The results were compared with operative findings in 18 patients with subsequent surgical repair. Eighteen patients with conservative therapy had a follow-up MR examination after 3 months. There was 1 sprain, 3 partial and 32 complete tears of the anterior talofibular ligament, and 5 sprains, 5 partial, and 7 complete tears of the calcaneofibular ligament. There were no lesions of the posterior talofibular ligament. Compared with surgery, MRI demonstrated in 18 of 18 cases the exact extent of anterior talofibular ligament injuries and underestimated the extent in 2 of 8 cases of calcaneofibular ligament injury. In patients with follow-up MRI after conservative therapy, a thickened band-like structure was found along the course of the injured ligament in 17 of 18 cases. The absence of ligament repair after conservative treatment was confirmed during operative revision in one case. The MRI technique allows for grading of the extent of injury of the lateral collateral ligamentous complex after acute ankle strain. It seems to be suitable for monitoring the healing process after conservative-functional treatment of ligament tears.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050703
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  • 3
    Electronic Resource
    Electronic Resource
    Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man (1996)
    Springer
    European journal of clinical pharmacology 50 (1996), S. 225-230 
    Details
    ISSN: 1432-1041
    Keywords: Key words Coumarin (1 ; 2-benzopyrone); grapefruit juice ; scopolin ; scopoletin ; umbelliferone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: Grapefruit juice is known to inhibit mammalian cytochrome P450 isozymes such as CYP3A4. The aim of this study was to investigate the influence of the juice on the fate of coumarin (1,2-benzopyrone) metabolized by CYP2A6 in man. Its potentially inhibitory effect was examined when low and high amounts of grapefruit juice were taken. Methods: In crossover studies, doses of 10 mg coumarin (Venalot) were given orally to a healthy male volunteer. The drug was taken either with water or with grapefruit juice, at different volumes (300 ml or 4 × 250 ml at intervals of 30 min). Urine samples were collected up to 24 h after dosing. After in vitro hydro-lysis they were analysed fluorimetrically for umbelliferone, the metabolite of coumarin, and cumulative excretion curves were established. HPLC and TLC served to identify fluorescent metabolites from the juice. Results: If coumarin is given in water its excretion is complete after 6 h and 70% of the dose is recovered. Grapefruit juice (300 ml) given simultaneously slightly retards the appearance of the fluorescent metabolite in the urine within the first few hours. The recovery of coumarin remains unaffected. One litre of juice enhances the delay and increases the recovery of coumarin to nearly 100%. Respective controls with grapefruit juice alone lead to remarkable excretions of a fluorescent material identified as conjugated scopoletin, which strongly interferes with the analysis of the coumarin experiment. The precursor of scopoletin is widely present at different concentrations in commercially available grapefruit juices. However, the autoinhibition of the juice is correlated neither to the concentration of naringin nor to that of scopoletin. Conclusion: Only grapefruit juice given at high doses (1 L) retards the appearance of the main metabolite of coumarin administered orally but increases its reco-very. Due to scopoletin formed from the grapefruit juice, experiments especially with coumarin are strongly affected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050097
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  • 4
    Electronic Resource
    Electronic Resource
    Ergebnisse nach primärer ungebohrter Tibianagelung von Unterschenkelfrakturen mit schwerem offenem oder geschlossenem Weichteilschaden (1996)
    Springer
    Der Unfallchirurg 99 (1996), S. 771-777 
    Details
    ISSN: 1433-044X
    Keywords: Schlüsselwörter Primäre ungebohrte Tibianagelung ; Unterschenkelfraktur ; Offener Weichteilschaden ; Geschlossener Weichteilschaden ; Key words Primary unreamed nailing ; Tibial fractures ; Open soft tissue injury ; Closed soft tissue injury
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Primary stabilization was performed in 72 tibial fractures with severe open (n = 37) or closed (n = 35) soft tissue injury using unreamed interlocking nails. In 60 (83%) cases the fractures healed without additional procedures. There were 2 cases of osteitis, but both these fractures healed after removal of the nail or after reamed nailing. In 9 patients with delayed union reamed nailing (n = 8) or bone grafting (n = 1) led to healing. In 1 patient with hypertrophic pseudarthrosis, union was achieved after substitution of a reamed nail for the anreamed nail. The infection rate was similar to that observed with external fixation. More secondary procedures, such as bone grafting or a change of the osteosynthesis technique, are necessary with external fixation than with unreamed nailing. Further advantages of unreamed nailing are the internal treatment of the fracture and the patient's greater comfort. Therefore, unreamed nailing can be recommended for the primary treatment of tibial fractures with severe open or closed soft tissue trauma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050054
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  • 5
    Electronic Resource
    Electronic Resource
    Kernspintomographische Untersuchung thorakolumbaler Wirbelfrakturen nach Fixateur-interne-Stabilisierung (1997)
    Springer
    Der Unfallchirurg 100 (1997), S. 524-530 
    Details
    ISSN: 1433-044X
    Keywords: Schlüsselwörter Thorakolumbale Wirbelfraktur ; Instabilität ; Bandscheibendegeneration ; Magnetresonanztomographie ; Key words Thoracolumbar fracture ; Instability ; Disc degeneration ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: To analyse the possible injuries of vertebral segments, especially the disc, after unstable thoracolumbar fractures stabilised with AO internal fixator, we performed magnetic resonance imaging (MRI) of the traumatised region after implant removal. There were two aspects of disc degeneration (DD): (1) biochemical changes and (2) structural damage. MRI detects biochemical processes as one aspect of DD that is often small even in the presence of greater structural damage of the nucleus pulposus caused by fracture. None of the patients presented with structural failure of the anulus fibrosus, which is the essential structural component of the vertebral segments with regard to stability. We observed biochemical changes more often in the lower of the two fracture-adjacent discs and alterations of discal shape more often in the upper of the two, whereas loss of height concerned both discs to approximately the same degree. The supporters of upper-disc resection in thoracolumbar fractures justify their procedure among other things with the structural disc damage, such as alteration of shape and loss of height (altogether more frequent in the upper disc). Our observations that a disc with a structurally altered nucleus pulposus can be biochemically intact and can show an intact anulus fibrosus are arguments in favour of disc preservation. With regard to the upper disc, the widespread opinion that complete and regular disc damage requires a resection has to be revised. The question of whether the lower disc should be resected more often because of its greater biochemical changes cannot be answered by the present study alone. Besides the excellent static information in all anatomical structures of the vertebral column available by MRI, a repeat examination in a prone position yields dynamic information on the spinal cord in the case of suspected dorsal adhesions.
    Notes: Zur Analyse möglicher Unfallfolgen an vertebralen Bewegungssegmenten und insbesondere der Bandscheiben nach instabilen, mittels Fixateur interne versorgten thorakolumbalen Wirbelfrakturen führten wir bei 33 Patienten eine Magnetresonanztomographie (MRT) der Verletzungsregion nach der Implantatentfernung durch. Bei der Bandscheibendegeneration nach instabilen thorakolumbalen Wirbelfrakturen sind strukturelle von biochemischen Veränderungen zu unterscheiden. Die mittels MRT bestimmbare biochemische Degeneration findet sich deutlich seltener als ein morphologischer Schaden des Nucleus pulposus. Verletzungen des Anulus fibrosus, der eigentlich stabilisierenden Struktur der vertebralen Bewegungssegmente, wurden bei keinem Patienten beobachtet. Im Vergleich zur frakturbenachbarten oberen Bandscheibe ist der untere Diskus nach Ausheilung der Fraktur zwar weniger von Veränderungen der Form, jedoch häufiger von biochemischer Abnutzung und etwa gleich stark von Höhenverlust betroffen. Die Befürworter einer Resektion der oberen Bandscheibe bei der operativen Behandlung thorakolumbaler Wirbelfrakturen begründen ihr Procedere u. a. mit dem strukturellen Bandscheibenschaden, wie z. B. Höhenverlust und Impaktierung von Bandscheibengewebe in den Wirbelkörper, die in der Summe häufiger bei dem frakturbenachbarten oberen Diskus beobachtet werden. Unsere Beobachtungen, wonach eine Bandscheibe trotz morphologischer Schädigung des Gallertkerns einen dennoch biochemisch intakten Nucleus pulposus und strukturell unversehrten Anulus fibrosus aufweisen kann, sprechen eher für den Erhalt des betreffenden Diskus. Für die frakturbenachbarte obere Zwischenwirbelscheibe (seltener biochemisch degeneriert) bedeutet dies, daß die weitverbreitete Ansicht von der regelmäßigen Zerstörung und demzufolge obligaten Resektion zu überdenken ist. Die Frage, ob die untere Bandscheibe bei nachgewiesenermaßen ausgeprägter biochemischer Degeneration entsprechend häufiger reseziert werden sollte, kann durch die vorliegende Studie allein nicht beantwortet werden. Neben der statischen Beurteilbarkeit sämtlicher anatomischer Strukturen der Wirbelsäule in der MRT liefert die Wiederholung der Untersuchung in Bauchlage eine dynamische Information über das Verhalten des Rückenmarkes bei Verdacht auf dorsale Adhäsion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050152
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  • 6
    Electronic Resource
    Electronic Resource
    Pseudarthrosen (2000)
    Springer
    Der Unfallchirurg 103 (2000), S. 51-63 
    Details
    ISSN: 1433-044X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Als Pseudarthrose bezeichnet man eine Fraktur, die nach acht Monaten noch nicht geheilt ist. Unterschieden werden aseptische von infizierten sowie vitale von avitalen Pseudarthrosen. Ursächlich für die Entwicklung einer Pseudarthrose können biologische und/oder mechanische Gründe sowie eine Infektion sein. Neben der klinischen und laborchemischen Diagnostik ist eine Röntgenuntersuchung obligat. In unklaren Fällen kann eine weiterführende Diagnostik mit Röntgenschichtaufnahmen, CT, Szintigraphie oder MRT erfolgen. Die Art der erforderlichen Behandlung wird davon abhängig gemacht, welche Ursache für die Entstehung einer Pseudarthrose gefunden wird. Hypertrophe vitale Pseudarthrosen verlangen eine stabile Osteosynthese. Avitale Pseudarthrosen benötigen dagegen eine Anfrischung der Pseudarthrose und autologe Knochentransplantation, ggf. ergänzt durch eine Reosteosynthese. Infektpseudarthrosen können meist nur durch mehrfache Eingriffe erfolgreich behandelt werden, die nach einem Stufenkonzept durchzuführen sind. Als Gold-Standard muß bis heute die operative Therapie angesehen werden. Alternative Verfahren wie ESWL (Extrakorporale Stoßwellen), Elektrostimulation, Ultraschalltherapie oder BMP (Bone Morphogenetic Protein) können zur Knochenheilung führen, ihr Stellenwert muß jedoch noch durch größere klinische Studien geklärt werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050008
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  • 7
    Electronic Resource
    Electronic Resource
    The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human (1997)
    Springer
    European journal of clinical pharmacology 53 (1997), S. 265-269 
    Details
    ISSN: 1432-1041
    Keywords: Key words Naringin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: Constituents of grapefruit juice are known to interfere with mammalian cytochrome P450 isozymes such as intestinal CYP3A4 and hepatic CYP2A6, lowering the biotransformation of drugs and increasing their bioavailability. The aim of this study was to investigate whether the presence of naringin is demanded for the inhibition of the coumarin 7-hydroxylase in man or other compounds are responsible for it. Methods: In cross-over studies, doses of 10 mg coumarin, together with combinations of grapefruit juice, water and naringin, were given orally to one healthy male volunteer. We investigated increasing amounts of grape-fruit juice, keeping the volume of liquid constant at 1 L; increasing doses of naringin given in water; increasing amounts of juice, keeping the dose of naringin constant; or increasing doses of naringin, keeping the amount of juice constant. Urine samples were collected up to 24 h after dosing and 7-hydroxycoumarin was quantified fluorimetrically in urine hydrolysates after HPLC separation to determine the excretion rates. Results: While increasing amounts of grapefruit juice delay the excretion of 7-hydroxycoumarin by 2 h, increasing doses of naringin in water up to twofold (i.e. naringin content of 2 L grapefruit juice) do not cause any alteration in the time course of excretion. Experiments with increasing amounts of juice, keeping the dose of naringin constant, indicate that the inhibitory potency of small amounts of grapefruit juice can be amplified by naringin. The same is true when the ratio between juice constituents and naringin is enhanced up to threefold by adding naringin. Conclusion: As naringin alone is ineffective, the inhibitory effect of grapefruit juice on the metabolism of coumarin is caused by at least one compound other than naringin. The persistency of the primary inhibitor not identified yet can obviously be modulated by the naring(en)in-system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050374
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  • 8
    Electronic Resource
    Electronic Resource
    Pathogenesis and prophylaxis of circulatory reactions during total hip replacement (1993)
    Springer
    Archives of orthopaedic and trauma surgery 112 (1993), S. 260-265 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Circulatory reactions such as a drop in blood pressure, bradycardia, cardiac arrest, and even intraoperative death after insertion of the stem are well known events during total hip replacement. The present paper reports bone marrow intravasation after rise of intramedullary pressure in the femoral cavity during insertion of hip protheses, demonstrated by intraoperative transesophageal echocardiography. In an animal study, the ultrasound echoes were identified as “mixed emboli” consisting of a core of bone marrow surrounded by thrombus. These results suggested the use of an intramedullary plug to restrict the intravasation of bone marrow. A trial was undertaken in 60 total hip replacement operations. The first 30 were performed using the conventional technique without an intramedullary plug. In a second series of 30 operations, an intramedullary plug made of cancellous bone taken from the resected femoral head was placed 2 cm below the expected location of the tip of the stem. The cement was applied from distal to proximal by syringe. After implantation of the prosthesis using the conventional technique, a significant drop in blood pressure was observed. In the second series, the drop in blood pressure did not occur. In conclusion, it was demonstrated that effective venting of the bone marrow cavity by a bore hole, and avoidance of compression of the bonemarrow-filled distal femoral cavity by using a plug, results in effective prevention of circulatory reactions: no drop in blood pressure occurred. The use of an intramedullary plug is discussed and recommended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00452961
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  • 9
    Electronic Resource
    Electronic Resource
    Magnetresonanztomographie des Kniegelenks mit einem Niederfeldsystem (1998)
    Springer
    Arthroskopie 11 (1998), S. 136-141 
    Details
    ISSN: 1434-3924
    Keywords: Schlüsselwörter Arthroskopie ; Kniegelenk ; Magnetresonanztomographie ; Key words Arthroscopy ; Knee-joint ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: The purpose of this study was to evaluate low-field magnetic resonance imaging (MRI) with an open system and to correlate results obtained with the experience of the radiologist. Between August 1995 and May 1997, 75 patients at the Unfallchirurgische Universitätsklinik, Mainz, Germany, with an acute trauma of the knee joint were operated on arthroscopically after clinical examination, X-ray and MRI imaging. MRI analysis was performed by two independent radiologists with varying MRI experience without knowledge of the patient’s history. The sensitivity and specifity of the more [U1] and the less experienced [U2] radiologist ranged from 83 to 100% (U1) and from 61 to 100% (U2). Positive and negative predictive value ranged from 83 to 100% (U1) and from 58 to 100% (U2); accuracy ranged from 92 to 100% (U1) and from 77 to 100% (U1). We conclude that the results of low-field MRI are comparable with those of high-field MRI and that differences in the results of the experienced and less experienced radiologist can be established.
    Notes: Ziel der vorliegenden Untersuchung ist die Evaluierung der Niederfeldmagnetresonanztomographie an einem offenen System unter Berücksichtigung des Erfahrungsstands des Untersuchers. In einer prospektiven Studie wurden von August 1995 bis Mai 1997 75 Patienten der Klinik für Unfallchirurgie der Universität Mainz mit einem akuten Trauma des Kniegelenks nach klinischer und konventionell-radiologischer Diagnostik magnetresonanztomographisch untersucht und anschließend diagnostisch und therapeutisch arthroskopiert. Die Auswertung der MRT-Untersuchungen erfolgte hierbei durch 2 unabhängige Untersucher unterschiedlichen Erfahrungsstands ohne Kenntnis der Anamnese bzw. des klinischen Befunds. Sensitivität und Spezifität der MRT-Befunde lagen beim geübten (U1) und weniger geübten (U2: in Klammern angegeben) Untersucher für U1 bei 83–100% (U2: 61– 100%). Der positive und negative prädiktive Wert lag für U1 bei 83– 100% (U2: 58–100%), und die Treffsicherheit wurde für U1 zwischen 92% und 100% (U2: 77– 100%) ermittelt. Es zeigte sich, daß die mit der Niederfeld-MRT erzielbaren Ergebnisse bezüglich der Diagnostik von Kniebinnenläsionen durchaus mit denen der Mittel- bzw. Hochfeld-MRT zu vergleichen sind. Deutliche Unterschiede bestehen in der vorliegenden Studie jedoch bezüglich der Abhängigkeit der diagnostischen Genauigkeit vom jeweiligen Untersucher.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001420050026
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  • 10
    Electronic Resource
    Electronic Resource
    Treffsicherheit der Magnetresonanztomographie zum Nachweis von Meniskusrissen (2000)
    Springer
    Der Unfallchirurg 103 (2000), S. 1079-1085 
    Details
    ISSN: 1433-044X
    Keywords: Schlüsselwörter Knie ; MRT ; Arthroskopie ; Meniskus ; Key words Knee ; MRI ; Arthroscopy ; Meniscus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In order to assure diagnostic accuracy, 172 knee joints were examined prospectively by MRI. After MRI, all knee joints were examined by arthroscopy. Tears of the medial meniscus were found in 102 patients, the lateral meniscus showed a tear in 29 cases. Assuming that arthroscopy represents the golden standard of diagnostic measure concerning the knee joint, it can be stated that false-positive MRI findings on the medial and lateral meniscus were diagnosed in three cases and false-negative MRI findings were diagnosed for two knee joints regarding the medial meniscus and four times regarding the lateral meniscus. For the medial meniscus a sensitivity of 98%, a specificity of 96%, an accuracy of 94%, and the positive and negative value of prediction were calculated at 97% each. Regarding the lateral meniscus, a sensitivity of 85%, a specificity of 98%, an accuracy of 92%, a positive predictive value of 88%, and a negative predictive value of 85% were found. Under the prerequisite that the MRI is carried out correctly and assessed by an experienced radiologist, the accuracy of the MRI for meniscus diagnosis is almost equivalent to the one by arthroscopy. Under these conditions, MRI can be recommended when no safe and sufficient clinical diagnosis can be made. The rate of unnecessary arthroscopies with a pure diagnostic purpose can be lowered significantly by means of MRI.
    Notes: Zusammenfassung Zur Überprüfung der diagnostischen Treffsicherheit wurden prospektiv 172 Kniegelenke mittels Magnetresonanztomographie (MRT) untersucht. Nach der MRT erfolgte bei allen Kniegelenken die arthroskopische Überprüfung der bildgebenden Diagnose. Rissbildungen des Innenmeniskus fanden sich bei 102 Patienten, am Außenmeniskus wurde 29-mal ein Riss befundet. Unter der Annahme, dass die Arthroskopie der “golden standard” diagnostischer Maßnahmen am Kniegelenk darstellt, ergab sich, dass falsch-positive MRT-Befunde am Innen- und Außenmeniskus in jeweils 3 Fällen und falsch-negative MRT-Befunde am Innenmenikus bei 2 Kniegelenken und am Außenmeniskus 4-mal erhoben wurden. Für den Innenmeniskus wurde eine Sensitivität von 98%, eine Spezifität von 96%, eine Genauigkeit von 94% und der positive bzw. negative Vorhersagewert mit jeweils 97% errechnet. Bezüglich des Außenmeniskus ließ sich eine Sensitivität von 85%, eine Spezifität von 98%, eine Genauigkeit von 92%, ein positiver Vorhersagewert von 88% und ein negativer Vorhersagewert von 85% ermitteln. Unter der Voraussetzung, dass die MRT korrekt durchgeführt und von einem erfahrenen Radiologen befundet wird, ergibt sich eine annähernd gleichwertige Treffsicherheit der MRT für die Meniskusdiagnostik wie mit der Arthroskopie. Die MRT kann daher unter diesen Voraussetzungen zur Anwendung empfohlen werden, wenn klinisch keine ausreichend sichere Diagnose zu stellen ist. Die Rate unnötiger rein diagnostischer Arthroskopien kann durch die MRT entscheidend gesenkt werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050672
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