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  • 1
    Electronic Resource
    Electronic Resource
    Input-increase and input-decrease types of cortical reorganization after upper extremity amputation in humans (1997)
    Springer
    Experimental brain research 117 (1997), S. 161-164 
    Details
    ISSN: 1432-1106
    Keywords: Key words Somatosensory ; Cortex ; Plasticity ; Amputation ; Magnetoencephalography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A plastic remodeling of regions in somatosensory cortex has previously been observed to occur in separate experimental paradigms in response to loss of somatosensory input and to increase in input. In this study, both types of cortical reorganization have been observed to occur concurrently in the same adult human nervous system as a result of a single intervention. Following upper extremity amputation, magnetic source imaging revealed that tactile stimulation of the lip evoked responses not only in the area of the somatosensory cortex corresponding to the face, but also within the cortical region that would normally correspond to the now absent hand. This “invasion” of the cortical amputation zone was accompanied by a significant increase in the size of the representation of the digits of the intact hand, presumably as a result of an increased importance of sensory stimulation consequent to increased dependence on that hand imposed by the loss of the contralateral extremity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002210050210
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  • 2
    Electronic Resource
    Electronic Resource
    Changed perceptions in Braille readers (1998)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 391 (1998), S. 134-135 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The mature mammalian nervous system has a striking capacity for plastic remodelling in response to environmental changes, but little is known about the perceptual and behavioural relevance of this phenomenon. Using magnetic source imaging we show that the cortical somatosensory representation ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/34322
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Electrophysiological evidence for cortical plasticity with movement repetition (2005)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 21 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The role of movement repetition and practice has been extensively studied as an aspect of motor skill learning but has rarely been investigated in its own right. As practice is considered a prerequisite for motor learning we expected that even the repetitive execution of a simple movement would rapidly induce changes in neural activations without changing performance. We used 64-channel event-related potential mapping to investigate these effects of movement repetition on corresponding brain activity in humans. Ten healthy right-handed young adults performed a power grip task under visual force control to ensure constant behaviour during the experimental session. The session consisted of two parts intersected by a break. For analysis each part was subdivided into two runs to control for potential attention or fatigue effects, which would be expected to disappear during the break. Microstate analysis revealed that distinct topographies and source configurations during movement preparation, movement execution and feedback integration are responsive to repetition. The observed patterns of changes differed for the three microstates, suggesting that different, repetition-sensitive neural mechanisms are involved. Moreover, this study clearly confirms that movement repetition, in the absence of skill learning, is capable of inducing changes in neural networks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2005.04045.x
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    Paper (German National Licenses)
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