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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 110 (1996), S. 487-492 
    ISSN: 1432-1106
    Keywords: EEG ; Voluntary movement ; Auditory ; Steady-state response ; Evoked response ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It has not been clear whether or not early information processing in the human auditory cortex is altered by voluntary movements. We report a movementrelated, complex event-related potential consisting of relatively long-lasting amplitude and phase perturbations induced in an ongoing auditory steady-state response (SSR) by brief self-paced finger movements. Our results suggest that processing in the auditory cortex during the first 50–100 ms after stimulus delivery is affected before, during, and after voluntary movements, beginning with a 1- to 2-ms delay in the SSR wave form starting 1–2 s before the movement.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: Viually-induced gamma-band responses ; Coherency ; Evolutionary spectra ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Visual presentation of an object produces firing patterns in cell assemblies representing the features of the object. Based on theoretical considerations and animal experiments, it has been suggested that the binding of neuronal representations of the various features is achieved through synchronization of the oscillatory firing patterns. The present study demonstrates that stimulus-induced gamma-band responses can be recorded non-invasively from human subjects attending to a single moving bar. This finding indicates the synchronization of oscillatory activity in a large group of cortical neurons. Gamma-band responses were not as apparent in the presence of two independently moving stimuli, suggesting that the neuronal activity patterns of different objects are not synchronized. These results open a new paradigm for investigating the mechanisms of feature binding and association building in relation to subjective perception.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1106
    Keywords: Key words Somatosensory ; Cortex ; Plasticity ; Amputation ; Magnetoencephalography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A plastic remodeling of regions in somatosensory cortex has previously been observed to occur in separate experimental paradigms in response to loss of somatosensory input and to increase in input. In this study, both types of cortical reorganization have been observed to occur concurrently in the same adult human nervous system as a result of a single intervention. Following upper extremity amputation, magnetic source imaging revealed that tactile stimulation of the lip evoked responses not only in the area of the somatosensory cortex corresponding to the face, but also within the cortical region that would normally correspond to the now absent hand. This “invasion” of the cortical amputation zone was accompanied by a significant increase in the size of the representation of the digits of the intact hand, presumably as a result of an increased importance of sensory stimulation consequent to increased dependence on that hand imposed by the loss of the contralateral extremity.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Performance and event-related potentials (ERPs) were examined in a proactive interference (PI) task with 15 male schizophrenic patients and 15 matched healthy controls. Within a paired-associate task, 30 pairs of semantically unrelated words (A-B) were presented twice, followed by cued recall, in which the paired-associate B had to be named upon cue A. Subsequently, 50% of the A-words were paired with new words (A-C) and presented in random order together with 15 novel pairings (D-E). Slower responses and poorer recall of C- than of E-words in the final recall indicated PI in both groups. During acquisition, the paired-associates (C/E) evoked larger P3 and positive slow wave in controls than in patients. During recall, cues (A/D) evoked a slow wave with predominating anterior negativity in controls and posterior positivity in patients. The group-specific ERP pattern suggests deviant encoding and retrieval processes in schizophrenic individuals.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing
    Psychophysiology 37 (2000), S. 0 
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: With the advent of dense sensor arrays (64–256 channels) in electroencephalography and magnetoencephalography studies, the probability increases that some recording channels are contaminated by artifact. If all channels are required to be artifact free, the number of acceptable trials may be unacceptably low. Precise artifact screening is necessary for accurate spatial mapping, for current density measures, for source analysis, and for accurate temporal analysis based on single-trial methods. Precise screening presents a number of problems given the large datasets. We propose a procedure for statistical correction of artifacts in dense array studies (SCADS), which (1) detects individual channel artifacts using the recording reference, (2) detects global artifacts using the average reference, (3) replaces artifact-contaminated sensors with spherical interpolation statistically weighted on the basis of all sensors, and (4) computes the variance of the signal across trials to document the stability of the averaged waveform. Examples from 128-channel recordings and from numerical simulations illustrate the importance of careful artifact review in the avoidance of analysis errors.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing
    Psychophysiology 40 (2003), S. 0 
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: A new set of techniques allows for the study of brain function by near-infrared light, exploiting two optical phenomena: Changes in light absorption are determined by changes in the concentration of substances like oxy- and deoxy-hemoglobin, and changes in light scattering occur as a consequence of variations of properties of membranes and corpuscles in the neural tissue. Methods based on light absorption can be used to study hemodynamic changes in the brain, whereas those based on light scattering can be used to study neuronal activity and to provide anatomical information at a cellular and subcellular level. Three optical imaging approaches can be used to study living tissue: reflection, optical coherence tomography (OCT), and photon migration. These three approaches vary in their penetration (from less than a millimeter for reflection to up to 3–5 cm for photon migration) and spatial resolution (from a micron level for reflection and OCT to a millimeter and centimeter level for photon migration). This issue includes a collection of articles reviewing applications of these technologies to the study of brain and other bodily functions in humans.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The present study investigated the relationship between lateralized sensorimotor activation and lateralized elevation of electrodermal activity. Within a two-stimulus reaction time paradigm skin conductance responses (SCRs) were recorded from both hands, while subjects awaited and performed unilateral sensorimotor tasks. A tactile warning stimulus was applied 6 s prior to a tactile imperative stimulus either to the same or to the contralateral hand; the imperative stimulus was associated with a choice reaction time task.Task-dependent lateral asymmetry with larger skin conductance responses contralateral to the involved hemisphere indicated contralateral facilitatory processes rather than inhibition. This asymmetry disappeared with repeated stimulation (across trials). Only right-hand (left hemispheric) tasks proved to be sensitive to habituation.The asymmetry, recorded in slow brain potentials (SPs), assured that lateralized cortical processing was induced through the present experimental arrangement. The brain potentials specified the time course of lateralized processing, exhibiting larger late negative shifts at the precentral areas contralateral to the hand involved in the sensorimotor task and larger early negativity and a more pronounced positive evoked potential (late positive complex, LPC) contralateral to the hand stimulated by the tactile warning stimulus.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Slow event-related potentials (ERP) were examined in healthy and aphasic subjects in two-stimulus designs comprising a word comprehension and a rhyming task. Aphasics, though selected to perform above chance level, made significantly more errors and responded more slowly than controls, although canonical correlations did not indicate a statistical relationship between performance measures and ERP amplitudes. A discriminant analysis of ERP amplitudes distinguished the groups for the slow wave (SW; 0.5–1.0 s post-S1 onset) in the word comprehension, for the SW and the initial contingent negative variation (iCNV; 1.0–2.0 s post-S1 onset) in the rhyming task. Similarly for both tasks, ERP topography showed left-anterior predominance of the negative SW and iCNV in controls, whereas participants with aphasia showed smaller anterior and larger left-posterior amplitudes. The centroparietal terminal CNV (tCNV; 1 s pre-S2) was smaller in participants with aphasia than in controls, but similar in topography. Results suggest left-anterior activation for those language processes that were presumably provoked in the present tasks, like lexical access, or phonological encoding. The pattern of participants with aphasia may indicate effects of language impairment and recovery, but also consequences of the brain damage.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing
    Psychophysiology 39 (2002), S. 0 
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Hemodynamic and electrophysiological studies indicate differential brain response to emotionally arousing, compared to neutral, pictures. The time course and source distribution of electrocortical potentials in response to emotional stimuli, using a high-density electrode (129-sensor) array were examined here. Event-related potentials (ERPs) were recorded while participants viewed pleasant, neutral, and unpleasant pictures. ERP voltages were examined in six time intervals, roughly corresponding to P1, N1, early P3, late P3 and a slow wave window. Differential activity was found for emotional, compared to neutral, pictures at both of the P3 intervals, as well as enhancement of later posterior positivity. Source space projection was performed using a minimum norm procedure that estimates the source currents generating the extracranially measured electrical gradient. Sources of slow wave modulation were located in occipital and posterior parietal cortex, with a right-hemispheric dominance.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 28 (1991), S. 0 
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The present study employed event-related potentials (ERPs) of the brain to improve the understanding of temporal processing. A reproduction paradigm was realized by presenting a visual stimulus (illuminated screen) for intervals of varying length. A few seconds after presentation of such standard intervals the visual stimulus was switched on again and subjects were asked to reproduce the duration of the standard interval by turning off the illumination after a corresponding interval had elapsed. The length of standard intervals varied randomly with each of the following lengths being presented 20 times: 1, 2, 3, 4, 6, and 8 s. Reproduction was accurate for standard intervals up to 3 s but deteriorated with increasing interval length. Brain potentials during reproduction intervals of 1–3 s differed from those recorded during the longer intervals. A CNV-like slow negative shift developed during the shorter reproduction intervals. Negativity was reduced or even absent, when subjects had to reproduce standard intervals of 4 s or longer. The ERP results suggest that intervals shorter than 3–4 s may evoke a processing mode that is qualitatively different from the one dominating when periods in the range of several seconds have to be processed.
    Type of Medium: Electronic Resource
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