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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 48 (1976), S. 1386-1394 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 74 (1993), S. 3028-3046 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A high frequency, piezoelectric, laminated plate theory is developed and presented for the purpose of modeling and analyzing piezoelectric thin-film resonators and filters. The laminated plate equations are extensions of anisotropic composite plate theories to include piezoelectric effects and capabilities for modeling harmonic overtones of thickness-shear vibrations. Two-dimensional equations of motion for piezoelectric laminates were deduced from the three-dimensional equations of linear piezoelectricity by expanding the mechanical displacements and electric potential in a series of trigonometric function, and obtaining stress resultants by integrating through the plate thickness. Relations for handling the mechanical and electrical effects of platings on the top and bottom surfaces of the laminate are derived. A new matrix method of correcting the cutoff frequencies is presented. This matrix method could also be used to efficiently correct the cutoff frequencies of any nth order plate laminate theories which employ Mindlin's form of polynomial expansion of mechanical displacements and electric potential through the plate thickness. The first order laminated plate theory with correction factors for cutoff frequencies and slope of the flexural branch at large frequencies was applied to a 2-layer, zinc oxide-silicon strip, and a 3-layer, zinc oxide-zinc oxide-silicon strip. Open circuit, dispersion relations were generated for a range of volume fractions and compared to the exact dispersion relations.Both the 2-layer and 3-layer strip show similar qualitative comparison: The present theory compares fairly well with the exact dispersion relation for real wave numbers and nonpropagating (imaginary) wave numbers which are smaller than 0.5i. The extensional branch, and thickness-shear branches begin to deviate from the exact solution when the nondimensionalized frequency is greater than one. Consequently, to maintain accuracy of solutions when using the present first order laminated plate theory, one should limit the calculation of resonant, nondimensionalized frequencies to less than 1.1. Results for the frequency spectrum in the vicinity of the open circuit, fundamental thickness-shear frequency, and modes shapes were presented for the 2-layer strip with fixed edges, and a volume fraction of silicon equal to 0.2. The technically important fundamental thickness-shear mode is found to have the shear component strongly coupled with extensional component.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cardiovascular drugs and therapy 8 (1994), S. 95-99 
    ISSN: 1573-7241
    Keywords: hypertrophic cardiomyopathy ; arrhythmias ; ventricular tachycardia ; sudden death
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the management of hypertrophic cardiomyopathy the goals should be the control of symptoms, and the identification and treatment of those at high risk. Arrhythmias, particularly atrial fibrillation and nonsustained ventricular tachycardia, are common in adult patients with hypertrophic cardiomyopathy. Atrial fibrillation has long been thought to herald an ominous prognosis, but this is probably not the case, and in the majority of patients atrial fibrillation can be controlled without accelerated symptomatic deterioration. Uncontrolled observations indicate that low-dose amiodarone may be the most useful drug in both paroxysmal and chronic atrial fibrillation. The detection of nonsustained ventricular tachycardia on ambulatory ECG monitoring remains the single most useful indicator of the risk of sudden death in the adult patient, and the treatment of choice is again low-dose amiodarone. The mechanism of sudden death, and the mode of action of amiodarone in preventing it, are not known for certain in the majority of patients. The risk of sudden death is higher in children and adolescents, but arrhythmias are less common, and no useful predictive marker of increased risk has been found. The roles of invasive electrophysiological studies and the implantable cardioverter-defibrillator are still being evaluated.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 29 (1991), S. 149-154 
    ISSN: 1741-0444
    Keywords: Cardiac energetics ; Coronary sinus flow ; Error analysis ; Left ventricular mechanical efficiency ; Thermodilution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A system to measure left ventricular heat productionΦ Iv in conscious human subjects is described. UsingΦ Iv and the rate of energy supply to the myocardium, the mechanical efficiency of the left ventricle is calculated. Heat carriage in left ventricular myocardial blood flowΦ CS is calculated from coronary sinus flow and the transcoronary temperature difference. Diffusional heat lossΦ diff is derived from the ratio of areas under temperature/time curves recorded in the aorta and coronary sinus after a bolus injection of cold saline into the pulmonary artery. The sum ofΦ cs andΦ diff (the energy of endothermic reactions with haemoglobin) givesΦ Iv . The estimated errors in the derived values of heat production and mechanical efficiency are less than 17 per cent. At basal heart rates 17 patients with good left ventricular function had a transcoronary temperature difference of 0·16±0·03°C (mean ± standard deviation), left ventricular flow blood flow of 145·3±81·5 ml min−1, andΦ Iv of 3·1±1·8 W. Left ventricular oxygen extraction was strongly correlated withΦ Iv (r=0.925, p〈0·001). Left ventricular mechanical efficiency was 0·33±0·11, at basal heart rates, which fell to 0·18±0·15 (p〈0·001) on atrial pacing at 100 beats min−1.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0935-6304
    Keywords: Capillary GC ; Cold on-column injection ; Splitless injection ; Automatic liquid sampler ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Biomedical Chromatography 8 (1994), S. 255-257 
    ISSN: 0269-3879
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A stereospecific HPLC method was developed for the analysis of (-) and (+) pentazocine in human serum. Each enantiomer and the internal standard nalophine were isolated from serum using a liquid-liquid extraction procedure. Recoveries of 99.05 ± 5.37 and 97.42 ± 2.78% were obtained for (-) and (+) pentazocine, respectively. Resolution of the enantiomers was obtained by using an ovomucoid chiral stationary phase with a mobile phase of methanol: acetonitrile: 10 mM phosphate buffer, pH 5.8 (20:5.3:74.7 v/v/v). A resolution (Rs) value of 1.80 was obtained for the pentazocine enantiomers. Linear calibration curves were obtained in the 10-100 ng/mL range for each enantiomer in serum. The detection limit based on a signal-to-noise ratio of 3 was 5 ng/mL for each enantiomer in serum using fluorescence detection with excitation at 275 nm and emission set at 335 nm. The lowest quantifiable level was found to be 10 ng for each enantiomer. Precision and accuracy of the method were in the 3.8-4.8% and 1.3-4.2% ranges, respectively.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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