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  • 1
    Electronic Resource
    Electronic Resource
    Primary leptomeningeal glioma: ultrastructural and laminin immunohistochemical studies (1992)
    Springer
    Acta neuropathologica 83 (1992), S. 538-542 
    Details
    ISSN: 1432-0533
    Keywords: Primary leptomeningeal glioma ; Ultrastructure ; Basal lamina ; Laminin ; Heterotopic glial tissue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied a case of primary leptomeningeal glioma (PLG) on the left parietal lobe of a 74-year-old woman and compared the tissue with heterotopic glial tissue from another case. The PLG tumor consisted of spindle-shaped cells with marked nuclear atypism, which tended to be arranged in a fascicular pattern, and the majority of its cells were positive for glial fibrillary acidic protein. Ultrastructural examination demonstrated that most of the tumor cells contained intermediate filaments and often junctional complexes were present on their plasma membranes. Frequently, basal lamina-like structures surrounding the tumor, cell surfaces were observed. Laminin immunohistochemistry clearly demonstrated a fine network of linear positive staining around the cytoplasm and processes of the tumor cells. The ultrastructure of the heterotopic glial tissue consisted of many astrocytes partially surrounded by basal lamina. These findings strongly suggest that PLG is a distinct tumor, which arises from the heterotopic astrocytes within the subarachnoid space.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310033
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Corticobasal degeneration: etiopathological significance of the cytoskeletal alterations (1994)
    Springer
    Acta neuropathologica 87 (1994), S. 545-553 
    Details
    ISSN: 1432-0533
    Keywords: Corticobasal degeneration ; Ultrastructure ; Tau ; Glial inclusions ; Progressive supranuclear palsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have studied brain tissues from three patients with corticobasal degeneration (CBD) histologically, ultrastructurally and immunohistochemically. Ballooned neurons in the cerebral cortex and severe degeneration of the substantia nigra were observed in them all and weakly basophilic neurofibrillary tangles (NFTs) were distributed widely in the basal ganglia and brain stem. Ultrastructural examination demonstrated that the NFTs comprised characteristic 15-nm-wide straight tubules, which showed positive immunohistochemical staining with an antibody against tau, but not ubiquitin. Tau-immunoreactive neuronal cell bodies without NFTs also were found in the cerebral cortex and subcortical nuclei, predominantly in the brain stem, and the greatest number of tau-positive glial inclusions occurred in the cerebral gray and white matter of the pre- and post-central gyri. These inclusions comprised tubular structures with diameters of about 15 nm and were localized in the oligodendroglial cellular cytoplasm and processes. These findings indicate that there is a close cytoskeletal pathological relationship between CBD and progressive supranuclear palsy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293314
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Corticobasal degeneration: etiopathological significance of the cytoskeletal alterations (1994)
    Springer
    Acta neuropathologica 87 (1994), S. 545-553 
    Details
    ISSN: 1432-0533
    Keywords: KeyWordsCorticobasal degeneration Ultrastructure ; Tau ; Glial inclusions Progressive supranuclear palsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have studied brain tissues from three patients with corticobasal degeneration (CBD) histologically, ultrastructurally and immunohistochemically. Ballooned neurons in the cerebral cortex and severe degeneration of the substantia nigra were observed in them all and weakly basophilic neurofibrillary tangles (NFTs) were distributed widely in the basal ganglia and brain stem. Ultrastructural examination demonstrated that the NFTs comprised characteristic 15-nm-wide straight tubules, which showed positive immunohistochemical staining with an antibody against tau, but not ubiquitin. Tau-immunoreactive neuronal cell bodies without NFTs also were found in the cerebral cortex and subcortical nuclei, predominantly in the brain stem, and the greatest number of tau-positive glial inclusions occurred in the cerebral gray and white matter of the pre- and postcentral gyri. These inclusions comprised tubular structures with diameters of about 15 nm and were localized in the oligodendroglial cellular cytoplasm and processes. These findings indicate that there is a close cytoskeletal pathological relationship between CBD and progressive supranuclear palsy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00293314
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Bilateral optic neuritis in a child diagnosed with Gd-enhanced MR imaging using fat-suppression technique (1999)
    Springer
    European radiology 9 (1999), S. 731-733 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Optic nerves ; Neuritis ; Children ; Central nervous system ; MR imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A 4-year-old boy developed bilateral optic neuritis. Although precise neuro-ophthalmological evaluation was difficult, the diagnosis was made with gadolinium-enhanced MR imaging using fat-suppression technique in the initial stage of the disease. Enhancement and enlargement of the intraorbital and intracanalicular optic nerve were demonstrated bilaterally as well as protrusion of the optic nerve head. The disease responded dramatically to intravenous steroid therapy. The etiologies in children usually differ from those in adolescent and adult patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050744
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  • 5
    Electronic Resource
    Electronic Resource
    Solitary plasmacytomas of the occipital bone: a report of two cases (1997)
    Springer
    European radiology 7 (1997), S. 503-506 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Skull ; Occipital bone ; Plasmacytoma ; CT ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The radiological appearances of two cases of solitary plasmacytoma in the occipital bone are described. One arose in the lateral part and the other in the squama. They showed characteristic radiological features on CT, MRI and angiography. Bone scintigraphy and gallium scintigraphy were also available. Solitary plasmacytoma of the skull is a rare condition and usually occurs in the calvarium. The skull base is an extremely rare site and only four cases have been reported. The literature of solitary plasmacytoma of the skull is reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050192
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    CT and MR imaging of the “target sign” in metastatic brain disease (2000)
    Springer
    European radiology 10 (2000), S. 154-156 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Metastatic brain tumors – Calcification – CT – MR imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The “target sign” is a common finding in granulomatous infection. A case with the target sign in metastatic brain tumor from small cell lung carcinoma is reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050024
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  • 7
    Electronic Resource
    Electronic Resource
    Solitary myofibromatosis of the skull (2000)
    Springer
    European radiology 10 (2000), S. 170-174 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Skull – Neoplasms – Infant – CT – MR – imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We present a case of solitary infantile myofibromatosis of the skull in a 3-month-old boy. A right parietal subcutaneous lump was found at birth, and it increased in size over the ensuing 3 months. Surgery was performed, and a diagnosis of myofibromatosis was confirmed histopathologically. Solitary myofibromatosis of the skull is extremely rare. The radiographical, CT, and MR appearances, as well as histopathological findings, are described in this article.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050028
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  • 8
    Electronic Resource
    Electronic Resource
    Diffusion-weighted echo-planar MR imaging in differential diagnosis of brain tumors and tumor-like conditions (2000)
    Springer
    European radiology 10 (2000), S. 1342-1350 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Brain ; MRI ; Neoplasms ; Diffusion image ; Echo-planar MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We assess diffusion-weighted MR images in the differential diagnosis of intracranial brain tumors and tumor-like conditions. Heavily diffusion-weighted (b = 1100 or 1200 s/mm2) axial images were obtained with single-shot echo-planar technique in 93 patients with pathologically confirmed various intracranial tumors and tumor-like conditions with diffusion gradient perpendicular to the images. We compared signal intensity of the lesions with those of gray and white matter, and cerebrospinal fluid (CSF). In 29 cases (31.1 %) the lesions were isointense to gray and/or white matter. However, 5 cases (5.4 %) showed extremely increased signal intensity: two epidermoid cysts; two chordomas; and one brain abscess. The entire portion of a tumor was markedly hyperintense in 10 cases (10.8 %): four malignant lymphomas; four medulloblastomas; one germinoma; and one pineoblastoma. A CSF-like hypointense signal was seen in many cystic tumors, and cystic or necrotic portions of tumors. A neurosarcoid granulation was the only solid lesion showing characteristically a hypointense signal like CSF. The combination of markedly hyperintense and hypointense signals was seen generally in hemorrhagic tumors. Diffusion-weighted echo-planar MR imaging is useful in the differential diagnosis of brain tumors and tumor-like conditions, and suggests specific histological diagnosis in some cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003309900310
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  • 9
    Electronic Resource
    Electronic Resource
    Fat in the dural sinus (1986)
    Springer
    Neuroradiology 28 (1986), S. 267-270 
    Details
    ISSN: 1432-1920
    Keywords: CT ; Dural sinus ; Lipoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fat density in the dural sinus on computed tomography (CT) is described in eight cases. Of the eight cases, five had fat deposit in the torcular Herophili, and three in the superior sagittal sinus. This finding was incidentally found by CT and there was no common underlying disease in these cases. It is suggested that this finding represents normal adipose tissue in the dural sinus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00548203
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Fat in the dural sinus-CT and anatomical correlations (1988)
    Springer
    Neuroradiology 30 (1988), S. 78-80 
    Details
    ISSN: 1432-1920
    Keywords: Lipoma ; Adipose tissue ; Dural sinus-CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Symmary Two cases of fat in midline dural sinuses, detected by high-resolution CT, were studied anatomically. The fat nodules were not located in the sinus lumen, but in the sinus wall. They were composed of normal adipose tissue without fibrous encapsulation. Our findings have proved that the fat deposit as demonstrated by CT within these dural sinuses represents normal adipose tissue in the sinus wall and does not necessarily mean the presence of a fatty tumor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341950
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