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  • Electronic Resource  (12)
  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 106 (1984), S. 4108-4111 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: Key words Spinal inhibition ; Interneurons ; Micturition ; Bladder-sphincter dyssynergia ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Micturition in the decerebrate cat is characterized by a coordinated bladder contraction and a simultaneous decrease in external urethral sphincter (EUS) efferent activity. Without the suppression of EUS activity, voiding is significantly impaired, resulting in a state sometimes referred to as bladder-sphincter dyssynergia. The aim of the present study was to determine whether glycinergic inhibition contributes to the suppression of EUS activity during micturition evoked by bladder distension or electrical stimulation of the pontine micturition center (PMC) in decerebrate cats. Using subconvulsive intravenous doses of strychnine (0.1–0.24 mg/kg), we examined changes in bladder and EUS electroneurographic (ENG) activity during micturition. Following subconvulsive doses of strychnine, tonic EUS ENG activity increased during bladder filling in five of six animals. In the presence of strychnine, it was possible to evoke reflex bladder contractions of similar duration and peak pressure to those observed before strychnine administration. However, there was an absence of suppression of EUS ENG activity during the bladder contractions in all the animals. To determine whether the changes in sphincter activity could be due to strychnine acting at glycine receptors on EUS motoneurons, sacral spinal tissue was processed for a structural protein (gephyrin) associated with the glycine receptor. Motoneurons in Onuf′s nucleus in S1 were identified using choline acetyltransferase immunohistochemistry and subsequently processed with a gephyrin monoclonal antibody. Abundant gephyrin labeling was evident throughout Onuf′s nucleus. Since Onuf′s nucleus is made up of EUS and other motoneuron populations, a sample of antidromically identified urethral and anal sphincter motoneurons were intracellularly labeled with tetramethylrhodamine dextran (TMR-D) and then processed with the gephyrin antibody. Using dual-beam confocal microscopy, gephyrin immunoreactivity was observed on the soma and proximal processes of individual EUS motoneurons in both male and female animals. It was concluded that a strychnine-sensitive mechanism contributes to the suppression of sphincter activity normally observed during voiding. Although glycinergic inhibition may affect several components of the circuitry responsible for micturition, it appears that the suppression of EUS motoneurons during micturition may be partly due to a direct glycinergic inhibition of the EUS motoneurons.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 87 (1983), S. 4840-4843 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 87 (1983), S. 5106-5113 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 72 (1992), S. 4041-4046 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Diffusion of an array of molecules in micrometer-thick films of plasma-polymerized tetrafluoroethylene has been measured using an optical interferometric technique. The diffusivity is approximately independent of molecular size up to a molar volume of about 100 cm3 and drops rapidly for larger molecules. For much larger molecules no penetration of the films is observed. These results suggest that plasma-polymerized tetrafluoroethylene films are heavily cross linked and that this limits the size of the molecules that can penetrate the polymer. The temperature dependence and the molecular size dependence of the diffusivities are discussed in the context of free-volume theory.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 87 (1983), S. 3638-3641 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 2326-2332 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Several physical properties of thin plasma-polymerized films have been measured using a new fiber-optic-based technique. Films of plasma-polymerized tetrafluoroethylene (PPTFE) deposited on the end of an optical fiber form an optical cavity, the reflectivity of which is very sensitive to the film thickness. The fiber is used as an in situ monitor of the deposition rate in the plasma and, after removal from the plasma, the mechanical properties of the film can be measured. With this measurement technique the thermal expansion of the film normal to its surface as well as the swelling of the film when exposed to an array of organic solvents have been determined. A significantly smaller thermal-expansion coefficient and larger degree of swelling are observed relative to bulk PTFE. X-ray photoelectron spectroscopy measurements show that the fluorocarbon chains are highly branched and have a fluorine-to-carbon ratio of 1.45. These results suggest that the plasma-polymerized films are not crystalline and are heavily cross linked.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 59 (1991), S. 2817-2819 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Swelling of micrometer thick-films of plasma-polymerized tetrafluoroethylene has been measured for a range of solvents using an optical-interferometric technique. For low gas-phase concentrations of the solvent, the swelling is found to correlate with the ionization potential of the solvent. Photo-thermal deflection spectroscopy of the films shows optical absorption in the infrared, which changes with exposure to different solvents. Both of these results suggest weak electron transfer from the solvent to the polymer as the dominant interaction mechanism.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 86 (1982), S. 3547-3553 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 7 (1971), S. 76-80 
    ISSN: 1432-0827
    Keywords: Pickets ; Bone ; Osteocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé Des couronnes périostéocytaires hypominéralisées au niveau de biopsies osseuses pratiquées, chez des patients, atteints de rachitisme résistant à la vitamine D, s'observent plus fréquemment autour d'ostéocytes jeunes que d'ostéocytes âgés. Ce fait indique qu'à un moment donné, cette hyperminéralisation périostéocytaire peut disparaitre et que, par consequence, il existe un intervalle de temps dans la minéralisation de la matrice organique périostéocytaire.
    Abstract: Zusammenfassung Höfe von schwach mineralisierten Periosteocyten werden in Knochenbiopsien von Patienten mit Vitamin D-resistenter Rachitis häufiger rings um die jungen als um die alten Osteocyten beobachtet. Es scheint somit, daß nach einiger Zeit die unvollständige Mineralisation, die auf Grund der Höfe angenommen werden werden kann, einen “Heilungsprozeß” erfährt und daß deshalb eine verzögerte Mineralisation der perlicunären organischen Matrix erfolgt.
    Notes: Abstract Udermineralized periosteocyte haloes in bone biopsies from patients with vtamin D-resistant rickets occur more frequently around young than around old osteocytes, indicating that in time the incomplete mineralization suggested by the haloes, undergoes a “healing” process and therefore there is a delay in the mineralization of the perilacunar organic matrix.
    Type of Medium: Electronic Resource
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