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  • 1980-1984  (2)
  • 1983  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Plasma membrane carbohydrate composition and lectin receptors of lymphocytes from Pro-lymphocytic leukaemia (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 941-945 
    Details
    ISSN: 1432-1440
    Keywords: Pro-lymphocytic leukaemia ; Plasma membrane ; Carbohydrate composition ; Lectin receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The carbohydrate composition of a purified plasma membrane fraction derived from the peripheral blood lymphocytes of a patient with a pro-lymphocytic leukaemia has been investigated and compared to the expression of lectin receptors at the membrane surface of the intact cell. The presence of galactose, mannose, fucose, glucose, sialic acid, N-acetylgalactosamine, N-acetylglucosamine and sialic acid substituted O-glycosidic linkedβ-D-galactopyranosyl (1 → 3) N-acetyl-D-galactosamine was confirmed on membrane glycoconjugates by gas chromatography. A lectin induced agglutinin assay using intact leukaemia cells demonstrated the accessibility of different lectin receptors at the native membrane surface, while the peanut agglutinin and the Helix pomatia receptor was only accessible after neuraminidase treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01550266
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Thrombopoese, Thrombozytenzahl und Thrombozytenfunktion vor und nach Zellseparation (1983)
    Springer
    Journal of molecular medicine 61 (1983), S. 969-973 
    Details
    ISSN: 1432-1440
    Keywords: Thrombopoesis ; Cell separation ; Platelet count ; Platelet function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary About 50% of the circulating platelets can be taken from healthy donors by means of the cell separation technique. In order to investigate the effect of cell separation on thrombopoesis bone marrow samples were taken from 12 voluntary donors up to 5 times. The megacaryocytes were analyzed before and after cell separation by morphometric measures and determinations of platelet count and platelet function (adhesion, aggregation, spreading, retraction) were carried out. Removing of large amounts of platelets form the circulation by stimulation of thrombopoesis resulted in an increase of the peripherical platelet count already 48 h after cell separation. Of the platelet functions tested only aggregation induced by collagen was found to be increased after cell separation as compared to that before the procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01550270
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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