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  • 2005-2009  (6)
  • 1980-1984  (1)
  • 1935-1939  (3)
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  • 1
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  The usefulness of bone marrow cells in accelerating wound healing has not been evaluated despite increasing evidence that bone marrow contains mesenchymal stem cells that have multipotentiality to differentiate into various types of cells after they enter the microenvironment of a specific tissue (niche).Objectives  To determine the effects of bone marrow cells and occlusive dressings in promoting wound healing in rats.Methods  We investigated by grafting, biopsy and immunohistochemistry whether various types of cells derived from green fluorescent protein (GFP)-transgenic rats would differentiate into wound component cells when administered topically on the wounds of rats. We also investigated whether topical application of bone marrow cells with an occlusive dressing would accelerate the healing of wounds with exposed bones, as measured by planimetry.Results  GFP-labelled bone marrow cells contained multipotent stem cells that sufficiently differentiated into wound myofibroblasts presenting with α-smooth muscle actin in granulation tissue. Other types of cells, including myocytes, adipocytes, peripheral blood cells from buffy coat and dermal fibroblasts, did not express myofibroblast characteristics morphologically or immunohistochemically. Application of bone marrow cells and an occlusive dressing accelerated the repair of wounds with exposed bones, compared with an occlusive dressing only or with the topical administration of bone marrow cells plus a semidry to dry dressing.Conclusions  Our study indicates that bone marrow cells accelerate the healing of wounds at least in part through their differentiation into wound myofibroblasts. Thus, treatment of wounds with bone marrow cells and a supportive occlusive dressing is effective in promoting the formation of healthy granulation tissue and also for the preparation of an ideal wound bed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 21 (2005), S. 0 
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The auditory evoked response is known to be changed by a preceding sound. In this study we investigated by means of magnetoencephalography how a preceding notch-filtered noise (NFN) with different bandwidths influences the human auditory evoked response elicited by the following test stimulus. We prepared white noise (WN) and four NFNs which were derived from WN by suppressing frequency regions around 1 kHz with 1/8-, 1/4-, 1/2- and 1-octave bandwidths. Stimulation for 3 s with this set of noises resulted in differences in responsiveness to a 1-kHz test tone presented 500 ms after the offset of the noises. The N1m response to the 1-kHz test tone stimulus was at a minimum when the preceding NFN had 1/4-octave stop-band frequencies as compared with 1/8-, 1/2- and 1-octave NFN and WN. This N1m decrement is explained by the imbalanced neural activities caused by habituation and lateral inhibition in the auditory system. The results contribute to understanding of the inhibitory system in the human auditory cortex.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Wounds with exposed bones caused by rheumatic diseases commonly result in amputation despite progress in our understanding of wound-healing mechanisms.Objectives  To determine whether an experimental therapy of bone marrow exposure, an occlusive dressing and subsequent grafting of epidermal sheets accelerates healing and reduces the need for amputation in patients with rheumatic diseases.Methods  Fifteen patients, including those with rheumatoid arthritis or systemic sclerosis, who had wounds with exposed bones were treated either with the standard procedure, consisting of local wound care, debridement with a scalpel, bed rest and parenteral antibiotics (n = 8), or with a newly developed experimental procedure (n = 7). In that new procedure, the affected bone was initially exposed by debridement with a scalpel, followed by partial excision with a bone scraper until bleeding was observed from the exposed bone. The lesions were immediately covered with an occlusive dressing, and were eventually treated with epidermal grafts obtained from suction blisters.Results  A comparison with standard therapy demonstrated that the time needed for wound healing was similar, but that the newly developed combination therapy reduced the risk of amputation (P = 0·020). No skin ulcers or erosions were observed for at least 1 year in five of seven patients (72%) due to the adoption of stable palmoplantar-type characteristics in grafts derived from the trunk epidermis.Conclusions  Our study indicates that exposure of bone marrow cells plus an occlusive dressing accelerates the healing of skin ulcers at least partly through the preparation of a healthy well-granulated wound bed and that subsequent epidermal grafting achieves site-specific differentiation through epithelial–mesenchymal interactions.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 327 (1984), S. 332-335 
    ISSN: 1432-1912
    Keywords: Vasopressin ; Carotid occlusion ; Cordotomized rats ; Paraventricular nuclei ; Arterial baroreceptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied the effect of carotid occlusion on blood pressure in cordotomized rats. Occlusion of both common carotid arteries resulted in an increase in blood pressure. This response was unaffected by denervation of the sinus and aortic nerves, and vagi. The response to occlusion was blocked by intravenous administration of a vasopressin antagonist, d(CH2)5 Tyr(Me)arginine-vasopressin, but not by intravenous administration of hexamethonium or captopril. Further, microinjection of procaine into the paraventricular nuclei abolished the pressor response to occlusion. Thus, it appears that in cordotomized rats carotid occlusion causes release of vasopressin and this in turn results in an elevation of blood pressure. The arterial baroreceptors are not essential for the pressor response.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 27 (1939), S. 278-279 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Notes: Zusammenfassung Es wurde röntgenographisch beobachtet, daß durch Erhitzungsbehandlung von gereinigten Ramiefasern, sowie der daraus erhaltenen Natrocellulose I mit Glyzerin bei 250° eine ziemlich deutliche Erhöhung des Orientierungsgrades der Kristallite in den nativen Fasern bewirkt wurde. Ein höchstorientiertes Präparat, welches ein besonders scharfes und deutliches Bild mit starker Annäherung an das Drehkristalldiagramm eines Einkristalls zeigt, wurde aus Natroncellulose durch die erwähnte Behandlung erhalten.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 27 (1939), S. 857-858 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Solid state phenomena Vol. 111 (Apr. 2006), p. 107-110 
    ISSN: 1662-9779
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Physics
    Notes: This study reports hydrogen absorption property of newly-synthesized RAP(rubeanic-acid polymer)-protected palladium nanoparticle (RAP-Pd). From powder X-ray diffraction measurements, the lattice constant of Pd nanoparticle was revealed to increase by 0.11 Å under 600 Torr hydrogen gas condition at room temperature, indicating that the hydrogen absorption occurs in the Pd nanoparticle. Solid-state 2H-NMR spectrum under deuterium gas showed that three different components exist in RAP-Pd, which are derived from imino group, terminal amino group in the RAP and absorbed deuterium atom inside the Pd nanoparticle. Thisresult gives an expectation of the hydrogen absorption in RAP itself
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 317-318 (Aug. 2006), p. 89-92 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: By the usage of the hydrolysis of Ti alkoxide, various types of TiO2 were obtained throughthe addition of catalyst (HCl, NH4OH, and CH3COONH4) and some additives into Ti alkoxidesolution at room temperature. In special, the effect of two additives, diethylene glycol (DEG) andhexamethylphospheric triamide (HMPA), on hydrolysis behaviors and microstructure with variouscatalyst for hydrolysis of Ti-tetraisopropoxide was in detail investigated. In case of TiO2 powder withHMPA as an additive, the crystallinity of TiO2 except with NH4OH as a catalyst decreased in XRDpatterns, compared to those of products with no additive and with DEG as an additive. The additionof HMPA prohibited the growth of TiO2 and led to fine TiO2 with the average particle size ofapproximately 10nm
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 317-318 (Aug. 2006), p. 247-250 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, the synthesis of nanotubular titanate was attempted though heat-treatmentin an oil bath (non-hydrothermal treatment), heat-treatment with stirring in an oil bath(non-hydrothermal treatment), or hydrothermal treatment for metal Ti in NaOH aqueous solutionsystems. Obtained products were characterized by various methods, such as X-ray diffraction(XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). XRDresults suggested that products obtained by both hydrothermal treatment and heat-treatment in an oilbath with and without stirring could be identified as H2Ti4O9[removed info]H2O. From TEM observations,however, various morphologies for products obtained by these treatments were confirmed.Therefore, it was considered that morphologies of these products strongly depended on synthesisconditions
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Colloid & polymer science 88 (1939), S. 62-68 
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Zusammenfassung 1. Die Umwandlung von Hydratzellulose in natürliche Zellulose auf dem Umweg über Alkalizellulose (Na-Zell. I, II, K-Zell. I, II und Li-Zell.) als Zwischensubstanzen konnte durch Erhitzungsbehandlung der letzteren mit Glyzerin auf höhere Temperatur (250° C) bewirkt werden, und zwar viel leichter und vollständiger als auf direktem Wege; es genügte dazu eine Erhitzungsdauer von nur 2∼3 Minuten. 2. Der Umwandlungsgrad des Umwandlungsproduktes steigt gemäß der folgenden Reihenfolge der Alkalizellulosen, über die diese Umwandlung durchgeführt wird: Kalizellulose 〈 Natronzellulose 〈 Lithionzellulose. 3. Die Röntgenbilder für die bei niedrigeren Temperaturen (150∼200°C) erhaltenen Präparate sind im allgemeinen unscharf. 4. Es wurde versucht, eine plausible Erklärung für die oben beschriebenen Befunde zu geben.
    Type of Medium: Electronic Resource
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