Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    The novel acute phase protein, IHRP, inhibits actin polymerization and phagocytosis of polymorphonuclear cells (2000)
    Springer
    Inflammation research 49 (2000), S. 305-310 
    Details
    ISSN: 1420-908X
    Keywords: Key words:Actin — Acute phase protein — IHRP — MAP — PK-120
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Objective and Design: In the present study, the involvement of the binding of IHRP (inter-alpha-trypsin inhibitor family heavy chain-related protein) and actin in phagocyte activity was investigated.¶Materials and Methods: The actin polymerization and the phagocytic activity of the polymorphonuclear (PMN) cells were studied in the presence of IHRP.¶Results: IHRP inhibited the polymerization of actin and the phagocytic activity of the PMN cells.¶Conclusion: 1) IHRP may bind to actin released from the damaged cells and suppress its toxic action by preventing the formation of actin fibril. 2) IHRP may bind to cell surface actin on PMN cells and inhibit their phagocytic activities. 3) From these results, IHRP may act as an anti-inflamma-tory protein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00000211
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Immunohistochemical detection of apolipoprotein E within prion-associated lesions in squirrel monkey brains (2000)
    Springer
    Acta neuropathologica 100 (2000), S. 365-370 
    Details
    ISSN: 1432-0533
    Keywords: Key words Amyloid ; Apolipoprotein E ; Prion ; Squirrel monkey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The interaction of various amyloid precursors and apolipoprotein E (apoE) is important for Congophilic amyloid formation. As for cerebral amyloidoses, although the correlation between amyloid β protein (Aβ) and apoE in Alzheimer’s disease (AD) has been clarified, the interaction of prion protein isoform (PrPsc) and apoE in several types of prion diseases (PDs) has not been examined in detail. ApoE colocalization has been confirmed in Congophilic PrPsc plaques, but to clarify the participation of apoE in the early stage of PDs, apoE deposition in immature lesions without Congophilic amyloid in PDs needs to be examined. In the present study two squirrel monkeys were inoculated with mouse PrPsc derived from sheep scrapie, and showed signs of severe spongiform degeneration. These lesions were immunohistochemically characterized as patchy perivacuolar and diffuse synaptic lesions without Congophilic amyloid. The central portion of the assemblies involving a few patchy perivacuolar lesions was detected by methenamine silver staining and appeared as a plaque-like lesion. ApoE was colocalized in all the plaque-like lesions and in half of the patchy perivacuolar lesions, but not in any diffuse synaptic lesions. These immunohistochemical characteristics indicated that apoE colocalization occurred in moderate mature lesions in PDs, and apoE might play an important role in the aggregation of PrPsc after a conformational change from cellular PrP isoform to PrPsc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010000200
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Evidence for anomalously small charge transfer in doped single-wall carbon nanohorn aggregates with Li, K and Br (2000)
    Springer
    Applied physics 71 (2000), S. 561-564 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 61.48.+c; 78.30.Na; 82.45.+z
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. Chemical doping of single-wall carbon nanohorns (SWNHs) with K and Br was examined by vapor-phase reaction and studied by Raman scattering. Electro-chemical Li-ion doping using an electrolyte of LiAsF6 in a mixture (1:1 by volume) of ethylene carbonate and diethyl carbonate was also carried out. All these experiments indicate that an anomalously small charge transfer occurs in saturation-doped SWNHs using these reagents, in sharp contrast to the behavior observed for single-wall carbon nanotube bundles and graphite. This rather remarkable result is not understood at present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390000681
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Benign teratoma in an 85-year-old woman (2000)
    Springer
    Archives of gynecology and obstetrics 263 (2000), S. 188-190 
    Details
    ISSN: 1432-0711
    Keywords: Key words Mature cystic teratoma ; Malignant transformation ; Advanced year
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Background: In women over the age of 50, a mature cystic teratoma is reportedly likely to change into a malignant form. A mature cystic teratoma that remained in a benign form in a very old woman is a rare event. We report a case of a benign cystic teratoma, which is the oldest in Japan. Case: An 85-year-old Japanese woman with a pelvic mass measuring 8.90×5.81 cm by ultrasonography was referred to our Department for detailed. Transvaginal ultrasonography, magnetic resonance imaging, and serum concentrations of tumor markers led to a diagnosis of a mature cystic teratoma. Histological findings postoperatively confirmed the presence of a mature cystic teratoma. Conclusions: This case report describes a mature cystic teratoma which is the second oldest case reported in the world. We reconfirmed that a mature cystic teratoma in elderly women is not frequent, but does occur.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004040050280
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Effects of mechanical stress on the volume phase transition of poly(N-isopropylacrylamide) based polymer gels (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 7640-7645 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The effects of mechanical stress on the volume phase transition of a poly(N-isopropylacrylamide) (PNIPA) gel as well as a copolymer gel composed of N-isopropylacrylamide (NIPA) and sodium acrylate (SA) were investigated in the relatively low stress region. The PNIPA gel without elongational stress showed the behavior close to the second order phase transition. The character of the first order transition became clear under tension, and the transition temperature increased with increasing applied stress. Similar behavior was observed for the NIPA-SA copolymer gel, but the copolymer gel showed the first order transition in the whole stress range investigated. The thermodynamical linear region, where the transition temperature varies linearly with applied stress, was narrower than the mechanical linear region determined by the stress–strain relation of the gels. The change in the transition behavior by the application of the mechanical stress originated chiefly from the volume change in the gels by the applied mechanical stress. It was found that the curve of the transition temperature against applied stress corresponds to the phase boundary between the swollen and collapsed phases for the gels. On the basis of the experimental data, a phenomenological model describing the volume phase transition of the polymer gels is proposed in the frame of the Landau-type free energy expression. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1312273
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Isolation of Peptides with Angiotensin I-converting Enzyme Inhibitory Effect Derived from Hydrolysate of Upstream Chum Salmon Muscle (2003)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 68 (2003), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: In order to utilize upstream chum salmon as a component of nutraceutical food, their defatted muscle proteins were hydrolyzed with 5% thermolysin. The resulting hydrolysate showed high inhibitory activity against angiotensin I-converting enzyme (inhibitory concentration50= 27.9 protein μg/mL) in vitro. A significant reduction of systolic blood pressure was observed when 500 and 2000 mg/kg of body weight were orally administered into spontaneously hypertensive rats. Angiotensin I-converting enzyme inhibitory peptides contained in the hydrolysate were isolated with various chromatographs. These 6 active peptides were Trp residue-containing dipeptides: Trp-Ala, Val-Trp, Trp-Met, Met-Trp, Ile-Trp, and Leu-Trp. The inhibitory concentration50 values of these dipeptides ranged from 2.5 μM to 277.3 μM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2003.tb12300.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Structural Changes in Titin and Nebulin Filaments Specific to Calcium Ions at 0.1 mM: Factors of Meat Tenderization During Postmortem Aging (2003)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 68 (2003), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Postmortem structural changes in titin and nebulin filaments were investigated by incubating isolated myofibrils in a solution containing 0.1 mM calcium ions and various concentrations of a protease inhibitor. The inhibition curves showed 2 abnormal steps with increases in the concentration of leupeptin or calpastatin domain I. While the amounts of unchanged titin and nebulin were constant in the 1st step, the 2nd occurred at higher protease inhibitor concentrations. These facts indicated that excess amounts of leupeptin and calpastatin domain I caused deterioration in titin and nebulin properties, thus interfering with the binding of calcium ions. We concluded that the severance of titin and nebulin filaments in the 1st step were induced by calcium ions at 0.1 mM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2003.tb08237.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Inactivity of μ-Calpain Throughout Postmortem Aging of Meat (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 67 (2002), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: : In order to determine the involvement of μ-calpain in the tenderization of meat during postmortem aging, μ-calpain was prepared from porcine skeletal muscle and its activity was measured under various conditions, using casein and myofibrils as the substrate. μ-Calpain was inactive at pH 5.89 and below 15 °C. Even when the reaction time was extended to 10 h, it was entirely inactive at pH 5.62 and 5 °C. In the early postmortem stage, when the pH value of muscle is above 6.0, μ-calpain was considered to be inactive due to the low concentration of sarcoplasmic calcium ions. μ-Calpain is, therefore, irrelevant to the tenderization of meat throughout postmortem aging.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2002.tb10651.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Tenderization of Heated Sliced Beef by Succinylated Glycerol Monostearate, a Novel Meat Tenderizer (2001)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 66 (2001), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Succinylated glycerol monostearate (SGMS) was most effective in reducing shear-force value when used as a surfactant to tenderize meat using sheep casings as a model of intramuscular connective tissue. Roasted beef slices that had been treated with 2% granular SGMS showed a marked decrease in toughness due to the penetration of SGMS along the perimysium during heating. Collagen fibrils in the perimysium were transformed into a sheet-like structure that seemed very likely to be a complex of SGMS and thermally denatured collagen. These structural changes could account for the tenderness of the roasted beef slices.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2001.tb04596.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Fast ignitor research at the Institute of Laser Engineering, Osaka University : The 42nd annual meeting of the division of plasma physics of the American Physical Society and the 10th international congress on plasma physics (2001)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 8 (2001), S. 2268-2274 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The physics element relevant to the fast ignitor in inertial confinement fusion has been extensively studied. Laser-hole boring with enormous photon pressures into overcritical densities was experimentally proved by density measurements with XUV laser probing. Ultra-intense laser interactions at a relativistic parameter regime were studied with a 50-TW glass laser system and a 100-TW glass laser system synchronized with a long pulse laser system. In the study of relativistic laser beam propagation in a 100-μm scale-length plasma, a special propagation mode (super-penetration mode) was observed, where the beam propagated into overdense regions close to the solid target surface. At the super-penetration mode, 20% of the laser energy converted to energetic electrons toward the target inside, while the coupling efficiency was 40% without the long scale-length plasmas. The high-density energetic electron transport and heating of solid material was also studied, indicating beamlike propagation of the energetic electrons in the solid target and effective heating of solid density ions with the electrons. Based on these basic experimental results, the heating of imploded plasma by short-pulse-laser light with three different ways of injecting the heating pulse has been studied. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1352598
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...