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  • 1
    Electronic Resource
    Electronic Resource
    Applications of Shape Memory Alloys in Japan (2000)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 327-328 (Jan. 2000), p. 17-22 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/04/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.327-328.17.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Diagnosis and molecular analysis of an atypical case of holocarboxylase synthetase deficiency (2000)
    Springer
    European journal of pediatrics 159 (2000), S. 18-22 
    Details
    ISSN: 1432-1076
    Keywords: Key words Biotin ; Holocarboxylase synthetase ; Multiple carboxylase deficiency ; Splice error
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Holocarboxylase synthetase (HCS) deficiency is a disorder of biotin metabolism characterised by metabolic ketoacidosis and skin lesions due to reduced activities of multiple biotin-dependent carboxylases. The onset of this disease is usually between the neonatal and infantile period. Here we report the molecular analysis of an atypical case of HCS deficiency, where the patient developed his first episode of acidosis at age 8 years and had an exceptionally slow response to biotin therapy. A homozygous mutation was identified at the +5 position of the splice donor site in intron 10 of the HCS gene (IVs10 + 5(g → a)), resulting in abnormal splicing of HCS mRNA. A moderate decrease in the amount of normal HCS mRNA may account for the atypical, late-onset phenotype of this patient. Conclusion Molecular analysis is a useful tool for understanding the phenotypic variations in holocarboxylase synthetase deficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050004
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  • 3
    Electronic Resource
    Electronic Resource
    Precision Grinding of SUS304 Using Metal Bonded CBN Wheel (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 24-25 (Sept. 2007), p. 261-264 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The fundamental experiment of the grinding of the stainless steel using the metal bondedCBN wheel which was excellent in wear resistance was conducted. The most appropriate grindingconditions were obtained by clarifying wear process of grinding wheel and finished ground surfacequality. When grinding was carried out up to stock removal 7000mm3/mm, radial wear of grindingwheel %R is 3μm and surface roughness Rz was 0.5μm or less. The grinding ratio Gr becomesabout 3000, and long life grinding with little change of surface roughness was possible
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.24-25.261.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Precision Grinding of High Chromium Steels Using Metal Bonded CBN Wheel (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 24-25 (Sept. 2007), p. 171-176 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, the influences of carbides and alloy additives on ground surfacecharacteristics of several high Chromium (Cr) steels and abrasive grains of working surface werediscussed. In the grinding using metal bonded CBN wheel, almost constant values in groundsurface roughness and high grinding ratio were shown. 5% Cr steel with Vanadium, 8% Cr steeland 10% Cr steel showed a rougher surface than Cr steels with 3%, 4% and 5% due to the carbideinclusion. The grinding ratio of 5%Cr steel could be raised considerably by adding sulfur to it
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.24-25.171.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    Magnetization Reversal by Spin-Polarized Current in Magnetic Tunnel Junctions with MgO Barriers (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Advances in science and technology Vol. 45 (Oct. 2006), p. 2633-2639 
    Details
    ISSN: 1662-0356
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Natural Sciences in General , Technology
    Notes: Co-Fe-B/MgO/Co-Fe-B magnetic tunnel junctions were fabricated using UHV magnetronsputtering. Magnetoresistance and spin-transfer switching properties were investigated as a functionof Co-Fe-B free layer thickness, between 1.5 nm and 3 nm. The intrinsic switching current andthe thermal stability were derived from the pulse duration dependence of the switching current,analyzed based on the thermally activated switching model. Both switching currents, correspondingto parallel (P) to antiparallel (AP) (Ic0+) and AP to P (Ic0–) magnetization reversal, were foundto be roughly proportional to the free layer thickness. The averaged intrinsic switching currentdensity Jc0av = (Ic0+–Ic0–)/(2A) (where A is the cell area) was in the range of 1–2×107 A/cm2. Theexperimental values of Jc0±agreed with theoretical values, determined taking into account the spintransferefficiency for the case of magnetic tunnel junction. The thermal stability of the P and APstates was different, but roughly proportional to the free layer thickness in both cases. We attributethis difference to a disparity in the net magnetic field acting on the free layer magnetization in the Pand AP states. The average of the thermal stability in the two states varied from 30 to 60 when thefree layer thickness was increased. According to our findings, to guarantee the non-volatility of anMRAM device for about 10 years, the Co-Fe-B free layer should be thicker than 2 nm
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/42/transtech_doi~10.4028%252Fwww.scientific.net%252FAST.45.2633.pdf
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  • 6
    Electronic Resource
    Electronic Resource
    Precision Grinding and Slicing of Glass-Like-Carbon (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 24-25 (Sept. 2007), p. 65-70 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: High density and isotropic poreless structure of Glass-like-carbon makes it practicallyused for fuel cells of space-shuttles and hard disk substrate etc. Glass-like-carbon is one of the newmaterials which attract attention, but it is so hard and brittle that precise machining of this materialis difficult. Surface grinding and slicing were performed to collect the fundamental data of precisemachining. The main results obtained in this study are as follows. (1) The transition from brittlemode to ductile mode in surface grinding occurs at a grain mesh size between #5000 and #3000.(2) The maximum grain depth of cut ‘dg’ necessary for ductile mode grinding is 0.021-0.006 mm orless. (3) When it is being sliced, the kerf width of the #1000 grinding wheel becomes wider thanthat of the #2000 grinding wheel because of the fact that the material removal capability of the#1000 grinding wheel is bigger than that of the #2000 grinding wheel. (4) It is extremely effectiveto use the fine grinding wheel, since the Young's modulus of glass-like-carbon is considerably lowand eventually causes compression transformation
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.24-25.65.pdf
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  • 7
    Electronic Resource
    Electronic Resource
    Elevation of Nitric Oxide Metabolites in the Cerebrospinal Fluid of Patients with Moyamoya Disease (2000)
    Springer
    Acta neurochirurgica 142 (2000), S. 1275-1280 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Collateral circulation; intracranial-extracranial bypass surgery; moyamoya disease; nitric oxide.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Background. To investigate whether nitric oxide (NO) contributes to formation of abnormal collateral circulation in patients with moyamoya disease.  Methods. Cerebrospinal fluid (CSF) samples were obtained from the subarachnoid space of the Sylvian fissure during combined bypass surgery for moyamoya disease and kept frozen until NO metabolites, nitrate and nitrite, were measured using a Griess method.  Results. Compared with control CSF obtained from 18 patients with hemifacial spasm, unruptured aneurysm, etc., concentrations of NO metabolites in 26 CSF samples of 18 patients with moyamoya disease were significantly higher (mean±SE; 17.6±1.2 vs. 10.5±1.0 μM, p〈0.01). In eight patients, the CSF samples from both the first and second operation could be obtained. NO metabolite concentrations (20.5±2.3 μM) in CSF obtained from the first surgery decreased to 15.7±1.8 μM (p〈0.01) in CSF obtained from the second, contralateral procedure. The cases of moyamoya disease with greater development of moyamoya vessels at angiographic stage 3 and 4 tended to show higher concentrations of NO metabolites than cases at earlier or later stages with a few moyamoya vessels.  Interpretation. Nitric oxide concentrations in CSF are chronically elevated in moyamoya disease, probably reflecting development of abnormal collateral circulation. i.e. moyamoya vessels. Vascular bypass surgery can reduce abnormal collateral circulation with reduced production of nitric oxide.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010070025
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  • 8
    Electronic Resource
    Electronic Resource
    Three-Dimensional Zinc Mapping inside Aluminum Foams Using Synchrotron X-Ray Microtomography (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 561-565 (Oct. 2007), p. 1677-1680 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Three-dimensional zinc mapping based on X-ray K-edge scanning has been performed.By microtomographies with energies above and below the K-absorption edges of the elements, theconcentration distribution of the elements is evaluated during in-situ experiments, respectively. It isfound that the Zn concentration distribution during the heat treatment was changed inside the cellwall of the aluminum foams and it has been homogenized. Also several precipitated phasetransformation can be three-dimensionally visualized by the CT-method tuning X-ray energies
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/18/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.561-565.1677.pdf
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  • 9
    Electronic Resource
    Electronic Resource
    Rapid and accurate identification of microorganisms contaminating cosmetic products based on DNA sequence homology (2005)
    Oxford, UK : Blackwell Science Ltd
    International journal of cosmetic science 27 (2005), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this study was to develop rapid and accurate procedures to identify microorganisms contaminating cosmetic products, based on the identity of the nucleotide sequences of the internal transcribed spacer (ITS) region of the ribosomal RNA coding DNA (rDNA). Five types of microorganisms were isolated from the inner portion of lotion bottle caps, skin care lotions, and cleansing gels. The rDNA ITS region of microorganisms was amplified through the use of colony-direct PCR or ordinal PCR using DNA extracts as templates. The nucleotide sequences of the amplified DNA were determined and subjected to homology search of a publicly available DNA database. Thereby, we obtained DNA sequences possessing high similarity with the query sequences from the databases of all the five organisms analyzed. The traditional identification procedure requires expert skills, and a time period of approximately 1 month to identify the microorganisms. On the contrary, 3–7 days were sufficient to complete all the procedures employed in the current method, including isolation and cultivation of organisms, DNA sequencing, and the database homology search. Moreover, it was possible to develop the skills necessary to perform the molecular techniques required for the identification procedures within 1 week. Consequently, the current method is useful for rapid and accurate identification of microorganisms, contaminating cosmetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-2494.2005.00285.x
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  • 10
    Electronic Resource
    Electronic Resource
    Two-dimensional numerical equilibria of field-reversed configuration in the strong mirror field (2000)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 4062-4069 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Two-dimensional numerical equilibria of field-reversed configuration (FRC) plasmas in the strong mirror field applied externally are studied by means of the Grad–Shafranov equation. Appropriate choice of the pressure function is necessary to obtain a thin and elongated equilibrium, as observed in the FRC Injection Experiment (FIX) [H. Himura et al., Phys. Plasmas 2, 191 (1995)]. To solve the Grad–Shafranov equation, the finite difference method is used, applying the boundary-fitted curvilinear coordinates and the attracted grids near the separatrix. The outstanding feature of the equilibria is the presence of a narrow and sharp spike in the toroidal current profile near the separatrix. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1289513
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