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  • 1
    Electronic Resource
    Electronic Resource
    Clinical and radiographic response of fourth ventricle cysticercosis to praziquantel therapy (1991)
    Springer
    Acta neurochirurgica 111 (1991), S. 135-137 
    Details
    ISSN: 0942-0940
    Keywords: Fourth ventricle ; cysticercosis ; praziquantel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of fourth ventricle cysticercosis treated with praziquantel is presented. The disappearance of the lesion six months after the treatment was demonstrated by CT scan. A review of the literature indicates that this is a very exceptional result, because with recently intraventricular cysticercosis was considered to be non-responsive to praziquantel treatment, making surgery necessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400502
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  • 2
    Electronic Resource
    Electronic Resource
    Control of Trypanosoma cruzi Infection in Mice Deprived of T-Cell Help (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 36 (1992), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The role of CD4+ T lymphocytes in the resistance of BALB/c mice to Trypanosoma cruzi was examined by in vivo depletion using monoclonal anti-CD4 antibodies (MoAbs)〈. When the administration of MoAbs was initiated 2 days before, or 5 to 12 days after the infeetion (dpi) with 50 bloodstream-from trypomastigotes of the Tulahun strain, mice showed an enhanced susceptibility to the parasite. Speeific IgM. but not IgM responses, were inhibited in anti-CD4-treated and infected miceHowever, when anti-CD4 treatment of mice was delayed until the 8th week of infection. neither a reactivation of the infection as determined by mortality or parasitaemia. nor a modulation of the titre of anti- T. cruzi IgG antibodies was detected. Furthermore, mice chronically infeeted with T. cruzi and deprived of CD4 or T cells resisted the challenge with 50,000 trypomastigotes (approximately 1000 LD50)Secondary antibody responses against parasite antigens were inhibited after in vitro depletion of CD4+ cells in chronically infected mice before boosting with T. cruzi antigens. However, recipients of CD4 or T-cell-depleled spleen cells from mice chronieally infected with T. cruzi were protected when challenged with the parasiteThe possibility that the parasite control is maintained by long-lived B cells capable of rapid differentiation into IgG-secreting plasma cells in the absence of T helper cells is discussed considering the present data
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1992.tb03098.x
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  • 3
    Electronic Resource
    Electronic Resource
    Glyphosate-tolerant CP4 and GOX genes as a selectable marker in wheat transformation (1995)
    Springer
    Plant cell reports 15 (1995), S. 159-163 
    Details
    ISSN: 1432-203X
    Keywords: Wheat ; transformation ; glyphosate ; CP4/GOX ; embryos
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The lack of alternative selectable markers in crop transformation has been a substantial barrier for commercial application of agricultural biotechnology. We have developed an efficient selection system for wheat transformation using glyphosate-tolerant CP4 and GOX genes as a selectable marker. Immature embryos of the wheat cultivar Bobwhite were bombarded with two separate plasmids harboring the CP4/GOX and GUS genes. After a 1 week delay, the bombarded embryos were transferred to a selection medium containing 2 mM glyphosate. Embryo-derived calli were subcultured onto the same selection medium every 3 weeks consecutively for 9–12 weeks, and were then regenerated and rooted on selection media with lower glyphosate concentrations. Transgenic plants tolerant to glyphosate were recovered. ELISA assay confirmed expression of the CP4 and GOX genes in R0 plants. Southern blot analysis demonstrated that the transgenes were integrated into the wheat genomes and transmitted to the following generation. The use of CP4 and GOX genes as a selectable marker provides an efficient, effective, and alternative transformation selection system for wheat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00193711
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  • 4
    Electronic Resource
    Electronic Resource
    Increased density of oligodendrocytes in childhood ataxia with diffuse central hypomyelination (CACH) syndrome: neuropathological and biochemical study of two cases (1999)
    Springer
    Acta neuropathologica 97 (1999), S. 469-480 
    Details
    ISSN: 1432-0533
    Keywords: Key words Leukodystrophy ; Oligodendrocyte ; Myelin ; Orthochromatic ; CACH syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report neuropathological, biochemical and molecular studies on two patients with childhood ataxia with diffuse central nervous system hypomyelination (CACH) syndrome, a leukodystrophy recently defined according to clinical and radiological criteria. Both had severe cavitating orthochromatic leukodystrophy without atrophy, predominating in hemispheric white matter, whereas U-fibers, internal capsule, corpus callosum, anterior commissure and cerebellar white matter were relatively spared. The severity of white matter lesions contrasted with the rarity of myelin breakdown products and astroglial and microglial reactions. In the white matter, there was an increase in a homogeneous cell population with the morphological features of oligodendrocytes, in many instances presenting an abundant cytoplasm like myelination glia. These cells were negative for glial fibrillary acidic protein and antibodies PGM1 and MIB1. Some were positive for myelin basic protein, proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein, but the majority were positive for human 2′-3′ cyclic nucleotide 3′ phosphodiesterase and all were positive for carbonic anhydrase II, confirming that they are oligodendrocytes. Myelin protein and lipid content were reduced. The PLP gene, analyzed in one case, was not mutated or duplicated. The increased number of oligodendrocytes without mitotic activity suggests an intrinsic oligodendroglial defect or an abnormal interaction with axons or other glial cells. This neuropathological study supports the notion that CACH syndrome constitutes a specific entity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010051016
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  • 5
    Electronic Resource
    Electronic Resource
    In vivo diagnosis of Kufs’ disease by extracerebral biopsies (1998)
    Springer
    Acta neuropathologica 96 (1998), S. 102-108 
    Details
    ISSN: 1432-0533
    Keywords: Key words Adult ceroid lipofuscinosis ; Kufs’ disease ; Electron microscopy ; Extracerebral biopsies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In almost all of the earlier reported cases of Kufs’ disease, the adult form of ceroid lipofuscinosis, the diagnosis was ascertained by cerebral tissue examination, while peripheral biopsy examination revealed an apparent poor diffusion of specific lipofuscinic deposits, the finger print profiles (FPs). We report the ultrastructural data from skin, muscle and rectal biopsy specimens from two siblings, both still living, who present clinical features of Kufs’ disease. We observed the presence of FPs in locations that differ from the previous classic reports. Our results emphasize the value of extracerebral biopsies for the diagnosis of Kufs’ disease in vivo, and suggest some physiopathological assumptions based on vascular wall involvement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050866
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  • 6
    Electronic Resource
    Electronic Resource
    Solitary hamartomatous duodenal polyp; a different entity: Report of a case and review of the literature (1993)
    Springer
    Surgery today 23 (1993), S. 1074-1077 
    Details
    ISSN: 1436-2813
    Keywords: duodenal neoplasms ; hamartoma ; Peutz-Jeghers Syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Solitary hamartomatous duodenal polyps are a clinical entity considered until now to express an incomplete or initial form of Peutz-Jeghers syndrome (PJ syndrome). Following our experience of 1 case, we analyzed the clinical characteristics of the 12 previously reported cases of solitary hamartomatous duodenal polyps. In none of these cases did we find any documentation of mucocutaneous pigmentation, a family or personal history of intestinal polyps, or local neoplasic degeneration of the disease, and all cases presented during the fifth or sixth decade of life. Thus, we conclude that solitary hamartomatous duodenal polyps constitute a different entity to PJ syndrome, the most appropriate elective treatment for which is endoscopic electrosurgical polypectomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00309096
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  • 7
    Electronic Resource
    Electronic Resource
    A methodology for designing, modifying, and implementing Fourier transform algorithms on various architectures (1990)
    Springer
    Circuits, systems and signal processing 9 (1990), S. 449-500 
    Details
    ISSN: 1531-5878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract Fourier transform algorithms are described using tensor (Kronecker) products and an associated class of permutations. Algebraic properties of tensor products and the related permutations are used to derive variants of the Cooley-Tukey fast Fourier transform algorithm. These algorithms can be implemented by translating tensor products and permutations to programming constructs. An implementation can be matched to a specific computer architecture by selecting the appropriate variant. This methodology is carried out for the Cray X-MP and the AT&T DSP32.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01189337
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  • 8
    Electronic Resource
    Electronic Resource
    Clinical, biochemical, and molecular analysis of a maternally inherited case of Leight syndrome (MILS) associated with the mtDNA T8993G point mutation (1995)
    Springer
    Journal of inherited metabolic disease 18 (1995), S. 682-688 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report a new case of Leigh disease (subacute necrotizing encephalomyelopathy) in a girl with mitochondrial DNA (mtDNA) mutation in the ATPase6 gene at nucleotide position 8993. Sequence analysis of mtDNA revealed a T-to-G transversion at nucleotide position 8993 in the ATPase6 gene. Southern blot restriction analysis of patient muscle mtDNA showed only a mutant pattern for the mutation 8993. Molecular analysis of seven subjects from the family showed that except for the father they all carried the 8993 mtDNA mutation in all studied tissues, with high percentages in the two symptomatic children and even in one asymptomatic boy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02436757
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  • 9
    Electronic Resource
    Electronic Resource
    Nitrogen availability of soluble and slow release nitrogen fertilizers as assessed by electroultrafiltration (1993)
    Springer
    Nutrient cycling in agroecosystems 34 (1993), S. 121-126 
    Details
    ISSN: 1573-0867
    Keywords: Controlled release fertilizers ; electroultrafiltration ; nitrogen ; ryegrass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The efficiency of different nitrogenous fertilizers under forced leaching conditions was determined in pot experiments using ryegrass as an indicator plant in a sandy loam soil. Treatments were: ON (unfertilized), AN (ammonium nitrate), U (urea), DAP (diammonium phosphate), T (Triabon), FK (Floranid Komplett) and CDU (crotonylidendiurea). N source effects on N uptake, and N leached (as % of N applied) were evaluated. Results show that the fertilizers which behaved best with regard to N uptake were FK followed by Triabon and AN. The most soluble fertilizers, AN and urea, gave the highest N leaching losses. Significant correlations between EUF-NI (rapidly soluble fraction) and leaching, as well as between EUF-N (I + II) and N uptake by the plant (where EUF-N II relates to the slowly soluble fraction) were obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00750106
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  • 10
    Electronic Resource
    Electronic Resource
    Italian population data on the loci MR, GYPA, HBGG, D7S8 and GC (1996)
    Springer
    International journal of legal medicine 109 (1996), S. 161-162 
    Details
    ISSN: 1437-1596
    Keywords: PM loci (LDLR, GYPA, HBGG, D7S8, GC) ; PCR ; DNA polymorphism ; Population genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract Allele and genotype frequencies for the five loci LDLR, GYPA, HBGG, D7S8 and GC were determined for 374 unrelated Italians using a multiplex PCR-amplification and typing commercial kit. The distribution of the genotype frequencies showed no deviations from Hardy-Weinberg expectations. The combined power of discrimination and chance of exclusion for all five loci were 0.999 and 0.702, respectively. A test for homogeneity was performed and no significant differences were observed among the Caucasian population samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01369681
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