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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 8 (1978), S. 644-651 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mice exhibiting a spontaneous SLE-like lethal autoimmunity (female NZB/W hybrids) were given monthy doses of cyclophosphamide (CPA) 240 mg/kg p.o. starting at four months of age. Antibodies to DNA and sheep red blood cells (SRBC) were measured as well as general well being of the mice. The CPA-treated group demonstrated a marked increased in survival compared to the untreated controls with reduction of anti-DNA antibody levels but only a slight inhibition of the anamnestic response to SRBC immunization.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 83 (1991), S. 95-98 
    ISSN: 1432-0533
    Keywords: Creutzfeldt-Jakob disease ; Alzheimer's disease ; Amyloid ; Protease-resistant protein (PrP) ; Panencephalopathic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report a 69-year-old female with cerebral and cerebellar symptomatology of 15-month duration. At autopsy, both panencephalopathic Creutzfeldt-Jakob and plaque-predominant Alzheimer diseases were found. Plaque amyloid was exclusively of the β/A4 type, but abundant abnormal protease-resistant protein was identified by Western blot analysis of brain extracts.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 58 (1992), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: DM20 is an abundant CNS myelin-specific protein whose role in myelinogenesis is unknown. We have cloned the DM20 cDNA from adult mouse brain total RNA using the polymerase chain reaction and expressed it in HeLa cells. DM20, detected by immunofluorescence in stable transfectants, is present in some cells in large, intensely fluorescent intracellular clumps that probably represent elements of the rough endoplasmic reticulum and Golgi apparatus. Frequently, intense DM20 fluorescence could be detected at the plasma membrane. These findings are consistent with previous studies demonstrating that an intracellular “pool” of DM20 and its larger isoform, proteolipid protein, exists and that a substantial lag occurs between synthesis and insertion of these proteins into the expanding myelin membrane. Permanent DM20 expressors in contact with one another do not display any ultrastructural rearrangements at regions of cell–cell contact, in contrast to what we have previously reported for P0, a PNS-specific protein shown to mediate adhesion of the extracellular faces of the Schwann cell during PNS myelinogenesis. We believe that these results indicate that if DM20 is indeed an adhesion molecule, this property is likely to be significantly more subtle than P0-mediated adhesion.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 47 (1992), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Conflicting reports regarding the hazards of anaesthesia in children presenting for surgery with an upper respiratory tract infection have appeared in the literature. In the present study 130 children undergoing general anaesthesia with face mask for myringotomy and grommet insertion were graded as having either an acute or recent upper respiratory tract infection or were asymptomatic according to predetermined clinical symptoms and signs. The severity of respiratory and related complications were scored during induction, emergence and recovery. The peripheral oxygen saturation was recorded during induction, emergence, transfer to the recovery ward and in the recovery ward itself. There were no significant differences (p 〉 0.05) in the complication scores between the three groups of children. However, the incidence of hypoxaemia (oxygen saturation ± 93%) was significantly greater during transfer in the acute infection group (p = 0.001) and the recent infection group (p = 0.02), as well as during recovery in the acute group (p = 0.03) compared with asymptomatic children.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 86 (1979), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A method for recording the fetal electroencephalogram (EEG) during labour is described. Technical specifications for the construction of a suitable electrode are detailed. One hundred and twenty-three patients in labour were monitored using this technique and the success rate of obtaining records for analysis was 91 per cent.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 32 (1990), S. 399-406 
    ISSN: 1432-1920
    Keywords: MRI ; Phase imaging ; CSF flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Motion of the cerebrospinal fluid (CSF) in and around the brain and spinal cord was examined in healthy subjects and in a number of patients with abnormalities of the CSF circulation. The pulsatile motion of the CSF was determined by spin echo phase (velocity) imaging, sometimes in combination with gradient echo phase contrast cine. Differences in flow patterns across CSF spaces were observed: flow reversal in the cerebellomedullary cistern and lumbar area relative to cervical CSF, and in the posterior versus the anterior subarachnoid space in the spinal canal. Flow communication was demonstrated in known communicating cysts or cavities. Differences in flow were also noted across spinal narrowing or block, and across the walls of a variety of cystic lesions in the brain and spinal cord. MR phase imaging of CSF flow provides pathophysiological information of potential clinical importance for the assessment of diseases affecting the CSF circulation.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 45 (1992), S. 1537-1544 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Various conflicting reports in the literature regarding the effect of oxygen on the stability of vinyl acetate (VA) toward polymerization led us to reexamine this topic using both isothermal stability tests and quasi-adiabatic calorimetry. Both commercial VA stabilized with 5-20 ppm by weight of hydroquinone (HQ) and purified, unstabilized VA exhibit lower stability to thermally initiated polymerization (at 50-120°C) in the presence of oxygen than in its absence. However, when stabilized with 3-5 ppm of HQ, both air-saturated and oxygen-free VA exhibit adequate thermal stability at normal transport and storage temperatures (25-50°C). Oxygen destabilization of VA is probably caused by the relatively low stability of VA polyperoxide rather than by the oxidation of acetaldehyde impurity to peroxyacetic acid. The length of VA polymerization induction periods is about -0.4 order in oxygen partial pressure.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Sozial- und Präventivmedizin 23 (1978), S. 8-13 
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Jahre 1974 wurde in Grossbritannien ein Gesetz über Arbeitsmedizin und Arbeitssicherheit eingeführt, das das Problem neu angeht und die Organisation der Arbeitsmedizin und Arbeitssicherheit in diesem Land auf lange Sicht in starkem Masse beeinflussen wird. Der Zweck dieser Arbeit ist es, die diesem Gesetz zugrundeliegenden Prinzipien darzustellen, auf die Auswirkungen des neuen Gesetzes auf Arbeitgeber, Betriebsleiter, Arbeitnehmer und ihre Organisationen hinzuweisen, und die Entwicklung zu besprechen, die seit 1974 im Rahmen der Organisation der Arbeitsmedizin und Arbeitssicherheit als Resultat der neuen Gesetzgebung zu verzeichnen sind.
    Abstract: Résumé L'introduction en 1974 du «Britain's Health and Safety at Work Act» a marqué dans les conceptions et l'approche de l'hygiène et de la sécurité professionnelles un changement qui aura à long terme des effets importants sur l'organisation de ces disciplines. Le propos de ce travail est de souligner les principes généraux de cette approche, contenus dans l'Acte de 1974, de montrer les implications de ce nouvel Acte sur les organisations d'employeurs, de chefs d'entreprises, d'employés et de représentants de l'administration, de discuter les développements dans l'organisation de l'hygiène et la sécurité du travail qui en résultent.
    Notes: Summary Britain's Health and Safety at Work Act introduced in 1974 marked a change in approach to occupational health and safety which is having important long-term effects on the organization of occupational health and safety in Britain. The purpose of this paper is to outline the broad principles of approach to health and safety at work contained within the 1974 Act; highlight the implications of the new Act for employers, managers, employees, and representative organizations, and discuss the developments in the organization of occupational health and safety as a result of the 1974 Act.
    Type of Medium: Electronic Resource
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