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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 101 (1979), S. 3906-3916 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 107 (1985), S. 4547-4548 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 100 (1978), S. 2922-2923 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Microbial ecology 13 (1987), S. 269-271 
    ISSN: 1432-184X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 51 (1975), S. 381-389 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The frequencies and distribution patterns of chiasmata in the autosomal bivalents of Chorthippus brunneus are very similar in male and female meiosis. The mean cell chiasma frequency of oocytes is however significantly higher than that of spermatocytes, but this difference is almost certainly due to the incremental effect of the X bivalent on the chiasma frequencies of oocytes. The implications of these findings in terms of chiasma control are briefly discussed.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Differential staining of the sister-chromatids of meiotic chromosomes of Locusta migratoria was achieved following abdominal implantation of BrdU tablets and fluorescent plus Giemsa (FPG) staining of fixed and squashed testicular follicles. This paper presents a detailed analysis of crossover exchanges between light and dark chromatids in monochiasmate bivalents. Approximately half the bivalents studied had visible exchanges of dark and light chromatids associated with the chiasmata, as expected if chiasmata originate by breakage and rejoining exchange events between randomly selected non-sister chromatids. In all the bivalents studied the visible crossover exchanges coincided exactly with chiasmata thus showing that chiasma movement (terminalisation) does not occur subsequent to crossing-over in Locusta migratoria, and that chiasmata are therefore accurate indicators of crossing over. It was noted that a proportion (9.5%) of chiasmata were associated with apparently anomalous exchanges of dark and light chromatids which could not be explained by conventional crossing-over. Various hypotheses for the origin of these anomalous exchanges are considered.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 10 (1976), S. 231-236 
    ISSN: 1432-1041
    Keywords: Digoxin ; beta-methyl-digoxin ; capsules ; bioavailability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The intestinal absorption and urinary elimination rate of total cardioactive material was compared following digoxin and beta-methyldigoxin (BMD) administration to twelve healthy volunteers. Significantly more injected digoxin was recovered in urine. Urinary clearance was more rapid for digoxin, mean half-lives of elimination being 35 hours for digoxin and 40 hours for BMD. Calculated percentage intestinal absorption was lowest for digoxin tablets with a dissolution rate of 77% in one hour, intermediate for BMD tablets, and maximal for an experimental soft gelatin formulation of digoxin in solution. Respective mean values were 75%, 87% and 97%. Similar steady state plasma concentrations followed twice daily ingestion of the 0.25 mg digoxin tablets and 0.20 mg BMD tablets. Mean peak plasma concentration and percentage urinary recovery of ingested dose were higher during continued BMD administration. Between-subject variation in absorption was higher for the digoxin tablets. The comparative intestinal absorption of BMD and digoxin depends upon the formulation. Digoxin is virtually completely absorbed from a solution encapsulated in soft gelatin. Relatively more BMD is eliminated by nonrenal routes.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 86 (1987), S. 521-544 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Laser selective excitation and optical absorption studies of hydrogenated CaF2:0.05% Er3+ crystals have revealed 16 Er3+ ion sites involving H− or D− ion charge compensation. The relative occurrence of these sites can be controlled over a wide range by varying the duration of the hydrogenation treatment. The hydrogenic nature of these sites is established by the observation of local mode absorption lines in the infrared, Er3+ ion electronic line isotope shifts and associated local mode vibronic lines involving the H− and D− ions. Local mode infrared absorption frequencies of four sites are reported for most rare-earth ions. Five new Er3+−F− sites were identified in the laser selective excitation study. For 〈100〉 and 〈111〉 oriented crystals the fluorescence spectra of several of the sites exhibit well-defined polarization which determines their Er3+ ion site symmetries. Symmetry confirmations are also established for the two previously reported single Er3+ ion sites involving fluoride ion compensation. Eleven of the hydrogenic sites reported here are classified into two families, each derived from a single Er3+ ion site of the parent crystal, while three others are attributed to sites of nearly cubic Er3+ ion symmetry. Detailed spectroscopic results for these sites are presented, together with a crystal-field analysis for the C4v symmetry sites and some model assignments.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 88 (1988), S. 524-532 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A new experimental procedure for conducting reactive laser vaporizations is described and applied to the generation of the previously unreported copper radicals, 13CH3CuF, 12CH3CuF, HCuF, and DCuF, for rare gas matrix ESR investigations. Laser vaporization was conducted on a thin film of reactant condensed on the copper metal surface. The g and A tensors for these are compared with other small copper radicals in order to determine electronic structure and bonding trends. The neon magnetic parameters (MHz) for 13CH363CuF are: g(parallel) =1.965(1), g⊥ =2.3626(3); A(parallel)(63Cu) =3076(2), A⊥(63Cu) =2993(1); A(parallel)(19F) =94(1), A⊥(19F) =68(1); A(parallel)(13C) =19(1), A⊥(13C) 〈3. The H quartet hfs for CH3CuF was resolved on the perpendicular transitions, having an A value of 9.3(3) MHz. For H63CuF, the neon results (MHz) are: g(parallel) =1.975(1); g⊥ =2.4075(4); A(parallel)(63Cu) =2826(3), A⊥(63Cu) =2717(1); A(parallel)(19F) =127(2), A⊥(19F) =94(1); A(parallel)(H) =61(3), and A⊥(H) =29(1) MHz.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 1671-1678 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have studied the structure and optical stability of Te–Cu thin film alloy candidates for write-once optical recording. Films prepared by rf diode sputtering with 20–50 at. % Cu are amorphous, as-sputtered. One of these, Te65 Cu35 , has a relatively high crystallization temperature (150 °C), as determined by x-ray diffraction. Near the eutectic composition (∼29 at .% Cu), alloy films have stable optical properties after accelerated aging at 60 °C and 85% relative humidity. The mechanism for film stability near the eutectic was studied by x-ray photoelectron spectroscopy and depth profiling using ion scattering spectroscopy. We found that a Cu-enriched surface oxide, formed at ambient conditions, passivates the film and is responsible for its subsequent stability after accelerated aging. We also demonstrated that a 14 in. diam, multilayer optical disk with a Te65 Cu35 recording medium exhibits excellent linearity for 3 and 8 MHz pulses, good written pulse length stability, and high signal-to-noise ratio. Thus, a Te–Cu recording medium can effectively use run-length-limited codes, which allow very high data storage capacity and data transfer rates.
    Type of Medium: Electronic Resource
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