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  • 1
    Electronic Resource
    Electronic Resource
    Experimental bioprosthetic reconstruction of the trachea (1986)
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 215-223 
    Details
    ISSN: 1434-4726
    Keywords: Tracheal prosthesis ; Transplantation ; Bioprosthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We removed the tracheas from sacrificed laboratory animals and subjected this tissue to multistep chemical processing. This method allowed us to preserve the cartilage and reduce its antigenicity, thus creating a bioprosthesis very similar to the host tissue. By using allogeneic and xenogeneic prostheses so prepared, no signs of immune rejections were seen following heterotopic or orthotopic implantations. The transplanted cartilage remained stable for periods ranging up to 21 weeks in recipient rats, while partial morphologic integrity of the cartilage was seen up to 1 year in pigs. Reepithelialization of the transplant with ciliated epithelium was completed in all specimens 12–24 weeks following surgery. Segmental replacement of up to one third of the whole trachea was possible in rats, whereas similar segmental replacements failed in pigs. We also found that successful reconstruction of window-shaped defects was possible. We consider our tracheal bioprosthesis to be superior to cialit-preserved grafts and also to most other biological reconstruction procedures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00464433
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Analyzing power for elasticn-d scattering at 13 MeV (1989)
    Springer
    Few body systems 6 (1989), S. 151-156 
    Details
    ISSN: 1432-5411
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The analyzing power for elasticn-d scattering was measured atE n=13 MeV. The result is in good agreement with experimental data atE n =12 MeV andE n =14.1 MeV. At backward angles the data are well above the predictions of a rigorous Faddeev calculation using the Paris potential.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01089916
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  • 3
    Electronic Resource
    Electronic Resource
    354. Experimentelle untersuchungen zum einheilen von kreuzbandprothesen (1987)
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 955-955 
    Details
    ISSN: 1435-2451
    Keywords: Sheep ; Cruciate ligament ; Repair materials ; Biomechanics ; Schafe ; Kreuzband ; Ersatzmaterialien ; Biomechanik
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 98 Schafen wurde das vordere Kreuzband durch biologische oder/und synthetische Materialien ersetzt. Auf Grund der morphologischen und biomechanischen Ergebnisse werden gewisse Probleme der Prothesen vorgestellt: Design, Abrieb, Biokompatibilität, biologisches Einheilen und die Aussagekraft des makroskopischen Befundes im Vergleich mit biomechanischen Werten. Für die jeweiligen Prothesentypen spezifische Nachteile fordern eine strenge Indikationsstellung: die autologe Plastik erscheint immer noch überlegen.
    Notes: Summary In 98 sheep, the anterior cruciate ligament was replaced by biological or/and synthetic materials. Some of the problems with the prostheses were demonstrated by means of morphological and biomechanical results: design, wear, biocompatibility, biological healing, and the relation between the macroscopic aspect and biomechanical values. Specific complications in each type of prosthesis require definite indications: autologous repair still seems to be the best.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01298139
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  • 4
    Electronic Resource
    Electronic Resource
    333. Pankreasgangocclusion - vergleichende experimentelle Untersuchungen (1987)
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 944-944 
    Details
    ISSN: 1435-2451
    Keywords: Panreasocclusion ; Experiment ; Fibrin adhesive ; Pankreasocclusion ; Experiment ; Fibrinkleber
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An Ratten (n = 32) und Hunden (n = 6) wurde das exokrine Pankreas experimentell mit Fibrinkleber occludiert. Prolamin und Neoprene dienten als Kontrollsubstanzen. Bei Neoprene treten fortschreitende Fibrosen auf, Prolamin induziert eine granulomatöse Fremdkörperreaktion. Nach Occlusion mit Fibrinkleber findet sich eine leichte Fibrose; der Kleber ist nach 3 Wochen resorbiert. I.v. GTT und orale GTT bei Hunden zeigen keine Störung des Glucosemetabolismus. Der modifizierte Fibrinkleber dient somit als temporäres Occlusionsmittel, welches auch über Endoskope appliziert werden kann.
    Notes: Summary Fibrin adhesive has been used experimentally for duct occlusion in the pancreas of rats (n = 32) and dogs (n = 6). Prolamin and neoprene served as control materials: in the neoprene group progressive fibrosis was found; granuloma and foreign-body reaction were induced by prolamin. There was only mild fibrosis following occlusion with the fibrin adhesive, which is resorbed within 3 weeks. I.V. GTT and oral GTT in dogs demonstrated no impairment in glucose metabolism. Thus this modified fibrin adhesive can serve as a temporary occlusion material, which can also be applied in endoscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01298118
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  • 5
    Electronic Resource
    Electronic Resource
    305. Langzeitergebnisse mit einem kleinkalibrigen xenogenen bovinen Gefäßersatz (Solcograft-P ®) (1985)
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 709-709 
    Details
    ISSN: 1435-2451
    Keywords: Vascular prosthesis ; Microvascular surgery ; Bovine xenograft ; Gefäßprothesen ; Mikrogefäßchirurgie ; Bovines Xenograft
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In einer tierexperimentellen Studie wurde die Anwendbarkeit der neuen xenogenen bovinen kollagenen Gefäßprothese (Solcograft-P ®) als kleinkalibriger GefaBersatz (ø 〈 2 mm) untersucht. Beobachtungsdauer: 9 (n= 13), 12 (n=7) Monate. Untersuchungsmethoden: Angiographie, Histomorphologie, Rasterelektronenmikroskop. Die Durchgangigkeitsrate im untersuchten Kaliberbereich betrug insgesamt 95%. Das Prothesenkollagen wurde unter Neubildung von kollagenem und elastischem Bindegewebe teilweise abgebaut. Eine überschießende Neointimabildung war nicht zu beobachten. Die lumenseitige Auskleidung der Prothese erfolgte durch eine homogene endothelartige Zellschicht. In 30% der Fälle traten Verkalkungen bzw. Verknöcherungen auf. In einem Fall war eine aneurysmatische Dilatation in Prothesenmitte zu beobachten. Vor einer klinischen Anwendung sollte die biomechanische Belastbarkeit unter hypertensiven Kreislaufbedingungen überprüft werden.
    Notes: Summary In an animal model, we investigated the applicability of a new bovine vessel xenograft (Solcograft-P) as a small vascular substitute (ø 〈 2 mm). The observation intervals were 9 (n=13) and 12 (n=7) months. Examination methods included: angiography, light microscopy, and scanning electronic microscopy. The small-diameter xenografts examined had an overall patency rate of 95%. The prosthesis collagen was progressively substituted by newly formed collagenous and elastic connective tissue. Neointimal hyperplasia did not occur. The lumen-side surface was formed by an endotheliumlike cell layer. In 6 of 20 cases calcification and ossification were observed. In 1 case we saw an aneurysmal dilatation in the middle of the prosthesis. Before clinical application, the biomechanical properties should be examined under hypertensive circulation conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836903
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  • 6
    Electronic Resource
    Electronic Resource
    377. Histologische Beurteilung experimenteller mikrochirurgischer biliobiliärer Anastomosen (1986)
    Springer
    Langenbeck's archives of surgery 369 (1986), S. 872-872 
    Details
    ISSN: 1435-2451
    Keywords: Experimental microsurgical anastomoses ; Experimentelle mikrochirurgische Anastomosen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Autoren haben am Göttinger Minipig (n = 42) End-zu-End Anastomosen des Ductus Choledochus in mikrochirurgischer Technik mit Vicryl und Nylon 30 mm proximal der Papilla Vateri durchgeführt. Die Nähte erfolgten allschichtig, mucös oder extramucös. Mikrochirurgisch durchgeführte einreihige Mucosa-Nähte mit 8/0 Vicryl zeigten die bei weitem besten Ergebnisse. Die hat sich als geringe Narbenbildung, vollständigere Schleimhautregeneration, sowie sehr geringes Vorkommen des Zeichens der Cholestase in der Leber manifestiert.
    Notes: Summary End-to-end anastomoses were formed with a microsurgical technique using 30-mm vicryl and nylon proximal to the duodenal papilla in the Göttingen minipig (n = 42). The monofilament sutures were mucosal, extramucosal and all layer. The authors found that the 8/0 vicryl monofilament mucosal suture made by the microsurgical technique provides the best results. They also found that mucosal regeneration was perfect and cholestasis in the liver was rare.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01274697
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