ISSN:
1432-1041
Keywords:
ticlopidine
;
rheumatoid arthritis
;
sulphydryl levels
;
technetium index
;
erythrocyte sedimentation rates
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary In 22 patients with rheumatoid arthritis oral ticlopidine 250 mg/day for 18 months induced clinical improvement, confirmed by a significant decrease in the counts of involved joint. A significant decrease was observed in the technetium index (Tc-index) and the erythrocyte sedimentation rate (ESR), and a significant increase occurred in the serum sulphydryl (SH) levels. The long-term changes in serum SH and Tc-index produced by ticlopidine may represent a specific antirheumatic activity of this platelet-inhibiting drug.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00547416
Permalink