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  • 2005-2009  (4)
  • 1980-1984  (11)
  • 1
    Electronic Resource
    Electronic Resource
    ERYTHROCYTE GLYCOSPHINGOLIPIDS OF FOUR SIBLINGS WITH THE RARE BLOOD GROUP p PHENOTYPE AND THEIR PARENTS (1981)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 8 (1981), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Erythrocytes that exhibit the rare blood group p phenotype lack the P antigen (globotetraosylceramide) and the Pk antigen (globotriaosylceramide). This phenotype is inherited as an autosomal recessive condition and the red cells of heterozygous individuals, parents and children of p persons, are serologically normal but no chemical analyses of their red cells have been reported. We have studied an unusual family in which all five children exhibit the p phenotype. In addition to the abnormalities described previously, the erythrocytes of four siblings had twice the normal concentration of lactotriaoslyceramide and lactoneotetraosylceramide. These cells also contained 3-5 times as much sialosyllactoneotetraosylceramide and up to a two-fold increase in GM3 ganglioside. The glycolipids of the parents' erythrocytes were normal. Electrophoretic analysis of the glycoproteins of the proposita's erythrocytes revealed no abnormalities, but her erythrocyte membranes contained approximately 35% less galactosamine than normal red cells. This abnormality resulted from a marked decrease in galactosamine that was soluble in chloroformmethanol. The lipid-extracted residue, which contained the glycoproteins, had a normal galactosamine content.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1981.tb00940.x
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  • 2
    Electronic Resource
    Electronic Resource
    Overexpression of anti-apoptotic Mcl-1 in testicular germ cell tumours (2005)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 46 (2005), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aims:  To determine the expression of Mcl-1 in testicular germ cell tumours in order to clarify the role of this anti-apoptotic factor in these tumours. Various members of the Bcl-2 family have been implicated in the apoptotic mechanisms regulating germ cell apoptosis. Mcl-1 is an anti-apoptotic Bcl-2 family member and has recently been reported to be related to the progression of malignancy; however, the involvement of Mcl-1 in the development of germ cell tumours is still unknown.Methods and results:  Mcl-1 expression in testicular germ cell tumours was investigated by immunohistochemistry and reverse transcriptase-polymerase chain reaction (RT-PCR). By immunohistochemistry, overexpression of Mcl-1 was present in all germ cell tumours that were studied, including embryonal carcinoma and yolk sac tumour, as well as choriocarcinoma and teratoma. In teratomas, Mcl-1 was widely distributed in the epithelial, myogenic, neural and mesenchymal components. RT-PCR analysis after microdissection revealed high levels of Mcl-1 mRNA in all tumour variants compared with non-neoplastic germ cells.Conclusion:  Overexpression of anti-apoptotic Mcl-1 may function to enhance the viability of testicular germ cells, thereby leading to tumorigenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2005.02118.x
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  • 3
    Electronic Resource
    Electronic Resource
    Intracellular distribution of enzymes associated with nitrogen assimilation in roots (1981)
    Springer
    Planta 151 (1981), S. 457-461 
    Details
    ISSN: 1432-2048
    Keywords: Nitrogen assimilation enzymes ; Organelles, enzyme distribution ; Root
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The cellular distribution of enzymes involved in nitrogen assimilation: nitrate reductase (EC 1.6.6.2), nitrite reductase (EC 1.6.6.4), glutamine synthetase (EC 6.3.1.2), glutamate synthase (EC 2.6.1.53), and glutamate dehydrogenase (EC 1.4.1.3) has been studied in the roots of five plants: maize (Zea mays L. hybrid W 64A x W 182E), rice (Oryza sativa L. cv. Delta), bean (Phaseolus vulgaris L. cv. Contender), pea (Pisum sativum L. cv. Demi-nain), and barley (Hordeum vulgare L.). Initially, cell organelles were separated from soluble proteins by differential centrifugation. Cell organelles were also subjected to sucrose density gradients. The results obtained by these two methods indicate that nitrite reductase and glutamate synthase are localized in plastids, nitrate reductase and glutamine synthetase are present in the cytosol, and glutamate dehydrogenase is a mitochondrial enzyme.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00386539
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  • 4
    Electronic Resource
    Electronic Resource
    Benign pleomorphic adenoma arising in a parotid lymph node (1982)
    Springer
    Virchows Archiv 396 (1982), S. 351-356 
    Details
    ISSN: 1432-2307
    Keywords: Pleomorphic adenoma ; Lymph node ; Parotid gland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A rare case of a benign pleomorphic adenoma is reported, arising in a parotid lymph node in a 52-year-old woman. Serial sections showed that the tumor tissue was surrounded by a mantle of lymphoid tissue which had the essential characteristics of a lymph node. The pathogenesis of the lesion is discussed and the literature is briefly reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431393
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  • 5
    Electronic Resource
    Electronic Resource
    Experimental investigation of geologically produced antineutrinos with KamLAND (2005)
    [s.l.] : Nature Publishing Group
    Nature 436 (2005), S. 499-503 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The detection of electron antineutrinos produced by natural radioactivity in the Earth could yield important geophysical information. The Kamioka liquid scintillator antineutrino detector (KamLAND) has the sensitivity to detect electron antineutrinos produced by the decay of 238U and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature03980
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  • 6
    Electronic Resource
    Electronic Resource
    Brain dysfunction following vasospasm evaluated by somatosensory evoked potentials (1982)
    Springer
    Acta neurochirurgica 63 (1982), S. 53-58 
    Details
    ISSN: 0942-0940
    Keywords: Vasospasm ; somatosensory evoked potentials ; brain function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Somatosensory evoked potentials (SEP) were recorded in 9 patients with vasospasm caused by subarachnoid haemorrhage. There was a correlation between SEP changes and clinical outcome evaluated one month after onset. And, evaluation of SEP changes under induced hypertension or infusion of dehydrates was available to study the nature of ischaemic brain dysfunction caused by vasospasm. Furthermore, this study suggests that the available period of induced hypertension may be short in cases with severe clinical outcomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01728855
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  • 7
    Electronic Resource
    Electronic Resource
    Extensive evacuation of subarachnoid clot for prevention of vasospasm—Effective or not? (1982)
    Springer
    Acta neurochirurgica 63 (1982), S. 111-116 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of subarachnoid haematoma (clot) evacuation for the prevention of vasospasm (VS) in the acute stage was studied using 62 ruptured IC and MC aneurysm cases. Extensive clot evacuation within 48 hours after the onset did not prevent the development of VS but reduced the severity of VS, especially in the main trunks of the cerebral arteries (IC, M1, M2, A1). But excessive clot evacuation applied to the angry, swollen brain in the acute stage worsened the brain swelling and sometimes formed an intracerebral haematoma due to brain compression. The extent of the clot evacuation should be determined by preoperative CT findings and the brain's condition during the operation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01728862
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  • 8
    Electronic Resource
    Electronic Resource
    Surgical problems and pathophysiology in severe cases with ruptured aneurysm in the acute stage (1982)
    Springer
    Acta neurochirurgica 63 (1982), S. 163-174 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have managed 674 cases of ruptured aneurysms of the anterior part of the circles of Willis during the period 1969 to 1980. For this study, analyses were made to clarify the operative indication, timing and suitable procedures based on the pathophysiology of severe cases in the acute stage. Clinical results of conservative treatment in the era of delayed operation clearly show the inevitable necessity of early operation. The CBF measurement in the acute stage revealed a slight decrease of hemispheric CBF without regulatory dysfunction of cerebral circulation within 3 days of SAH. Results of early operation within 3 days of SAH in the 3rd era showed that 83.1% of cases survived with a good outcome and 3.4% died when they were in Grades 1 and 2. 40 cases with severe grading, operated on within 3 days of SAH, were studied on each site of the aneurysm. Mortality was 12.5% and there was a favourable outcome in 55%. Death was due to brain swelling caused by vasospasm and direct brain damage caused by SAH and an intracerebral haematoma. Extensive evacuation of subarachnoid clotting could be performed only when brain volume could be reduced enough to minimize brain compression, by using ventricular drainage, evacuation of the intracerebral haematoma and Mannitol administration. Surgical procedures for each aneurysm are also described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01728869
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  • 9
    Electronic Resource
    Electronic Resource
    Prevention of symptomatic vasospasm by topically applied Nimodipine (1982)
    Springer
    Acta neurochirurgica 63 (1982), S. 297-302 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 2.4×10−5M solution of the Calcium-antagonist Nimodipine was administered to the exposed cerebral vessels in 17 patients intraoperatively clipping of a ruptured aneurysm. The interval between subarachnoid haemorrhage and operation was 48 to 72 hours. The CT investigation had revealed blood accumulation in the basal cisterns in all cases. Vasodilatation was observed in all instances; the percentage being greater in small vessels as compared to large vessels. Postoperatively, a neurological deficit combined with angiographically verified vasospasm occurred in two patients, but was reversible in both. Fifteen patients remained free from symptomatic vasospasm and were discharged without neurological deficit. In 13 of these patients and 3 additional cases, a plastic cannula was placed intraoperatively so that postoperative topical administration of Nimodipine was possible. Postoperative control-angiograms after a mean interval of 7 days from SAH did not show severe spasm in any of the patients; localised moderate asymptomatic spasm was found in 8 cases and was reserved in 5. Moderate postoperative symptomatic spasm was observed in 2 patients, treated and reversed in one patient. In 5 of 7 cases without evidence of spasm in the angiogram postoperative topical administration of Nimodipine caused vasodilatation. It is concluded, that topical intracisternal administration of Nimodipine reverses intraoperative vascular spasm and decreases the probability of postoperative symptomatic vasospasm after early surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01728885
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  • 10
    Electronic Resource
    Electronic Resource
    Development of Gas-Atomized Magnetic Tools (2005)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 291-292 (Aug. 2005), p. 287-290 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The deficiency in the variety of available magnetic abrasive results in a narrow range of finishing performance. To break through this difficulty, this research developed iron-based gas-atomized magnetic tools. The magnetic tool has a spherical shape and micro-crevices on the surface. The micro-crevices perform the role of cutting instead of the edges of the existing magnetic abrasive, thereby achieving abrasive-less finishing. This paper studies the finishing performance ofthe developed magnetic tool. Compared to the existing magnetic abrasive, this magnetic tool shows more efficient finishing performance in the internal finishing of SUS304 stainless steel tubes used for sanitary piping systems
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/49/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.291-292.287.pdf
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