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  • 1
    Electronic Resource
    Electronic Resource
    MR imaging of mixed hepatocellular and cholangiocellular carcinoma (1994)
    Springer
    Abdominal imaging 19 (1994), S. 430-432 
    Details
    ISSN: 1432-0509
    Keywords: Mixed hepatocellular and cholangiocellular, carcinoma ; MR imaging ; Dynamic MR imaging-Histopathologic study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two patients with mixed hepatocellular and cholangiocellular carcinoma underwent partial hepatectomy after magnetic resonance (MR) imaging. Correlation is made with the histopathologic manifestations. In both cases the tumors showed relative low signal intensities on T1-weighted spin-echo (SE) images and high signal intensities on T2-weighted SE images. Dynamic MR imaging showed the enhancement from the periphery of the tumor to the inner area gradually and the enhancement continued into the delayed phase. With both cases fibrosis was marked in the inner area of the tumor compared to the peripheral area. The extent and degree of fibrotic tissue is considered to reflect the enhancement on dynamic MR imaging.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00206932
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  • 2
    Electronic Resource
    Electronic Resource
    Analysis of the circuitry responsible for primary afferent depolarization in the trigeminal spinal nucleus caudalis of cats (1977)
    Springer
    Experimental brain research 29 (1977), S. 405-418 
    Details
    ISSN: 1432-1106
    Keywords: Trigeminal nerve ; PAD ; Trigeminal spinal nucleus caudalis ; Interneuron ; Subnucleus magnocellularis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Depth analysis was performed on the field potential evoked by stimulation of the infraorbital nerve in the trigeminal spinal nucleus caudalis and the subjacent lateral reticular formation of cats. It was shown by dye marking of the recording positions that each subnucleus of the nucleus caudalis (subnucleus marginalis, gelatinosus and magnocellularis) and the reticular formation could be differentiated from one another by the characteristics of the peripherally evoked field potentials. Responses of neurons were extracellularly recorded in the subnuclei gelatinosus and magnocellularis of the nucleus caudalis and in the reticular formation to stimulation of the trigeminal sensory branches (the frontal, infraorbital and lingual nerves), the nucleus ventralis posteromedialis of the thalamus and the cerebral cortex. The properties of the neurons were studied in relation to their thresholds, latencies, receptive fields (sensory branches effective for spike generation) and frequency-following capacities. These responses were then compared with properties of the PAD induced in the fibers terminating in the nucleus caudalis by similar peripheral and central stimulation. It was found that the neurons in the subnucleus magnocellularis were the most likely candidates for the interneurons mediating the peripherally evoked disynaptic PAD in the trigeminal nerve fibers terminating in the nucleus caudalis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236179
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  • 3
    Electronic Resource
    Electronic Resource
    Primary afferent depolarization in the trigeminal spinal nucleus of cats (1977)
    Springer
    Experimental brain research 29 (1977), S. 45-56 
    Details
    ISSN: 1432-1106
    Keywords: Trigeminal nerve ; Primary afferent fiber ; Trigeminal spinal nucleus ; PAD ; Intra-axonal record
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intra-axonal recordings were made from trigeminal primary afferent fibers in the trigeminal spinal nuclei oralis and caudalis of cats. Primary afferent depolarization (PAD) was evoked in these afferents by stimulation of the trigeminal peripheral sensory branches (the frontal, infraorbital and lingual nerves), the cerebral cortex and the trigeminal spinal nucleus caudalis. The properties of the PAD, including the threshold, latency, receptive field (sensory branches effective for PAD induction) and frequency-following capacity, were studied with the following results: 1. Stimulation of all the peripheral branches tested as well as the cerebral cortex could evoke PAD in the same single fiber. The latency of the PAD evoked by stimulation of the nerve in which the fiber being recorded from was included was generally shorter than that evoked by other branches. The PAD evoked by peripheral nerve stimulation was assumed to be disynaptic in some cases. 2. The peripherally evoked PAD was chiefly attributable to low threshold afferents in the stimulated sensory branches of the trigeminal nerve. 3. The peripherally evoked PAD could follow stimulation at up to 30/sec, though the amplitude was reduced. 4. Stimulation of the nucleus caudalis could evoke PAD with disynaptic latency in the majority of the fibers terminating in the same nucleus, whereas it evoked PAD with mainly polysynaptic latency in the fibers terminating in the nucleus oralis. The results are discussed in relation to the neuronal circuitry responsible for induction of the trigeminal PAD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236874
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  • 4
    Electronic Resource
    Electronic Resource
    Management and subsequent 13-year progress of a mandibular fracture with malocclusion in a child – case report (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 18 (1991), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Under acute conditions, maxillofacial injuries may be treated without the opportunity for an assessment of occlusal irregularities, even when there are mandibular fractures, because life-threatening injuries have priority over occlusion. Consequently, mandibular fractures may result in post-trauma malocclusion and facial deformity.The case history reported is of amale patient who had been involved in a traffic accident in childhood and suffered mandibular fractures. The initial incomplete man- agement resulted in persistent deformation of the mandible, disturbance of dental occlusion and difficulty in mastication. These irregularities were corrected during childhood by non-operative orthodontic treatment.When the patient reached adulthood, some permanent teeth were malformed because the fractures had damaged some tooth germs. However, the permanent dentition in general was almost normal as a result of the corrected primary dentition. Although the alveolar deformity due to the injury remained, the mandibular base was satisfactorily remodelled.The case reported supports the view that early restoration of normal dental occlusion before the eruption of permanent teeth contributes to the establishment of good functional dental occlusion of the permanent teeth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1991.tb00048.x
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  • 5
    Electronic Resource
    Electronic Resource
    Development of the National Institute of Radiological Sciences electron cyclotron resonance ion source for the heavy ion medical accelerator in Chiba : Proceedings of the 5th international conference on ion sources (1994)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 65 (1994), S. 1087-1089 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The development of an electron cyclotron resonance ion source for the heavy ion medical accelerator in Chiba (HIMAC) injector is reported. The HIMAC is a heavy ion medical accelerator for cancer therapy. The electron cyclotron resonance (ECR) ion source is expected to provide a long lifetime, easy operation, and easy maintenance for medical use. The NIRS-ECR ion source has a single closed ECR stage, and a microwave frequency of 10 GHz is applied. Under the present performance, the output electrical currents of the ions are 2500 eμA for He1+, 300 eμA for C2+, 480 eμA for Ne3+, and 110 eμA for Ar6+. Stability of the intensity is better than 2%. The transmission efficiency through a low-energy beam-transport line with an acceptance of 200 πmm mrad is more than 70%; the typical 50% and 90% emittances of the injection beam with 8 keV/u are 20 and 80 πmm mrad, respectively. These performances satisfy the requirements for radiotherapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1145071
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  • 6
    Electronic Resource
    Electronic Resource
    Study of crystallographic orientations in the diamond film on cubic boron nitride using Raman microprobe (1990)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 57 (1990), S. 428-431 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have measured Raman spectra of a diamond film prepared on the (111) surface of cubic boron nitride(c-BN) by the dc plasma chemical vapor deposition method. The polarization property of the Raman line of diamond agrees well with that of LO phonon for the (111) surface of c-BN. The agreement between the polarization property of Raman lines of diamond and c-BN indicates a possibility of the heteroepitaxial growth of the diamond film on the (111) surface of c-BN. It is found that the diamond layers on c-BN are under tensile stress of 2.2×1011 dyn/cm2. The value of the corresponding tensile strain agrees well with the lattice mismatch calculated from the lattice constants of c-BN and diamond, supporting the possibility of the heteroepitaxial growth of the diamond film. Raman spectroscopy is a powerful technique not only to estimate the stress in the diamond film but also to determine the crystallographic orientation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.103656
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  • 7
    Electronic Resource
    Electronic Resource
    Epitaxial growth of diamond thin films on cubic boron nitride {111} surfaces by dc plasma chemical vapor deposition (1990)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 57 (1990), S. 563-565 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Diamond thin films have been grown epitaxially on high-pressure synthesized cubic boron nitride (c-BN) particles by using dc plasma chemical vapor deposition. At the early growth stage of the film on c-BN{111} surfaces, the island structure is observed and the number density of islands is about 1011 cm−2. The growth and the coalescence of islands are also found by scanning electron microscopy observation. The continuous film is obtained at the thickness of about 2000 A(ring) and the surface of the film is rather smooth. The Raman peak of the epitaxial diamond film shows the shift toward the lower wave number due to the tensile stress involved in the film.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.103647
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  • 8
    Electronic Resource
    Electronic Resource
    Immunohistochemical Localization of the Proteins Associated with Brain N-Type Calcium Channels (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 707 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb38075.x
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  • 9
    Electronic Resource
    Electronic Resource
    Global changes in gene expression related to antibiotic synthesis in Streptomyces hygroscopicus (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 6 (1992), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Two-dimensional gel electrophoresis was used to follow low changes in gene expression associated with antibiotic (bialaphos) biosynthesis in Streptomyces hygroscopicus. Cultures were pulse-labelled with [35S]-methionine before, during, and after the switch from primary to secondary metabolism in order to compare kinetic profiles of bialaphos (antibiotic) production (bap) genes during this metabolic transition. Separation of gene products on two-dimensional gels revealed that 27 were dependent on brpA for optimal expression and were activated as the culture approached stationary phase. Genes which encoded 10 brp4-dependent proteins were mapped to a 10 kb Sstl fragment of the 35 kb bap gene cluster by expressing them in Streptomyces lividans using the thiostrepton-inducible tipA promoter. N-terminal amino acid sequences of two brpA-dependent proteins, obtained by direct microsequencing of protein spots excised from two-dimensional gels, identified them as gene products mapping to the same region and involved in secondary metabolic conversions of the bap pathway. The kinetics of synthesis of 16 brpA-dependent gene products were characterized using QUEST computer software. Cluster analysis performed on the kinetics of synthesis of 346 of the most highly expressed gene products of HP5-29, including 16 brpA-dependent ones, identified 75 families having distinct patterns of expression. Many brpA-dependent proteins were clustered together; 10 were found in one kinetic family. These kinetic families also included brpA-independent gene products perhaps subject to similar regulatory mechanisms and thus possibly involved in bialaphos biosynthesis. The activation/derepression of bap expression took place as cultures approached stationary phase and was temporally related to synthesis of ppGpp.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1992.tb02163.x
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  • 10
    Electronic Resource
    Electronic Resource
    A γ-ray burst preceded by X-ray activity (1991)
    [s.l.] : Nature Publishing Group
    Nature 350 (1991), S. 592-594 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The first y-ray burst observed in the X-ray photon energy band was GB720427, which was detected in the 2-8 keV range4. X-ray data from GB720514 provided some evidence5 that an accompanying X-ray signal might have lasted longer than the y-ray event. Detailed X-ray observations of four catalogued ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/350592a0
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