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  • 1
    Electronic Resource
    Electronic Resource
    Quantitative analysis of the size distribution of target-and targetoid fibres employing the method of daeves and beckel for mixed distributions (1979)
    Springer
    Acta neuropathologica 45 (1979), S. 215-220 
    Details
    ISSN: 1432-0533
    Keywords: Skeletal muscle ; Denervation atrophy ; Target fibres ; Analysis of size distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An analysis of frequency distribution is performed in 250 target and targetoid fibres each from the anterior tibial muscle of a case with rapidly proceeding denervation atrophy. Following plane measurements on cross sections the size data were analysed according to the method of Daeves and Beckel [1] for mixed distributions. Three homogeneous normally distributed populations could thus be extracted from the mixed distributed sample. The largest population represents target fibres with a normal size range, while the second one encloses hypertrophic fibres, and the third and smallest one consists of fibres ranging within atrophic size limits. These findings support the previous presumption that targets predominantly occur in fibres of normal size and can therefore be regarded as manifestations of an early stage of denervation atrophy. The targetoid fibres, on the contrary, are of an atrophic size by 84%, while only a small population of about 15% contains targetoid fibres of a normal size on cross section.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00702673
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  • 2
    Electronic Resource
    Electronic Resource
    Vascular dementia in Spatz-Lindenberg's disease (SLD): cortical synaptophysin immunoreactivity as compared with dementia of Alzheimer type and non-demented controls (1993)
    Springer
    Acta neuropathologica 86 (1993), S. 259-264 
    Details
    ISSN: 1432-0533
    Keywords: Thromboangiitis obliterans ; Dementia ; Cortical synaptophysin expression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The generalized form of von Winiwarter-Buerger's disease (WBD) occasionally involves the brain. However, pure cerebral forms of the disease were also described by Spatz and Lindenberg (“Spatz-Lindenberg's disease”, SLD). Both, the type I, which involves the large basal arteries, and the type II, which results in a sickle-shaped granular atrophy of the cerebral cortex, are often accompanied by (“vascular”) dementia, which Lindenberg and Spatz mainly attributed to the bilateral involvement of the second frontal gyrus by granular atrophy. Recently, synaptic deprivation of the cortical gray matter has been shown to occur in the dementia of Alzheimer type (DAT) and other neurodegenerative disorders. In DAT, the synaptic loss highly correlated with the degree of the mental impairment. We wanted to examine whether similar changes also occurred in dementia of vascular origin, for which SLD, although infrequent, is a typical example. In fact, we found that in three cases of typical SLD type II the synaptophysin immunoreactivity of the cortical neuropil in areas without overt infarcts or scar formation was as much reduced as in Alzheimer's disease. Although it must be taken into account that in the present cases the synapse loss might, at least in part, be due to secondary (Wallerian) degeneration as a result of the neuronal loss in the “watershed” regions of the arterial blood supply, it cannot be excluded that a decline of cortical synaptic contacts in areas without necroses or scars may occur as a primary event, contributing to the pathogenesis of the dementia. Final conclusions can only be expected from investigations into further cases of cerebro-vascular disorders with and without dementia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304140
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  • 3
    Electronic Resource
    Electronic Resource
    Das Verhalten intraoperativ entstandener tiefer Venenthrombosen, beurteilt anhand wiederholter Phlebographien (1976)
    Springer
    Journal of molecular medicine 54 (1976), S. 521-526 
    Details
    ISSN: 1432-1440
    Keywords: Deep vein thrombosis ; phlebography ; postoperative ; fibrinogen test ; postthrombotic syndrom ; Tiefe Venenthrombose ; Phlebographie ; postoperativ ; Fibrinogentest ; postthrombotisches Syndrom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Rahmen einer prospektiven, randomisierten und kontrollierten Studie, in der die Thromboseprophylaxe-Mittel Dextran und Heparin bei allgemein-chirurgischen und urologischen Patienten geprüft werden, phlebographierten wir 31 Patienten mit sicherer tiefer Venenthrombose sofort nach der Diagnosestellung mittels125J-Fibrinogentest. 16 Patienten wurden 14 Tage später ein zweites Mal phlebographiert.Alle Thromben entstanden intraoperativ. 24 von 31 Patienten zeigten einemultifokale Entstehung der Thromben. Unabhängig vom Prophylaxe-Mittel und der eingeleiteten Therapie machten die Thromben in den ersten 14 Tagen nach deren Entstehung folgende Veränderungen durch: 9 retrahierten sich, 6 verschwanden, ohne Wandveränderungen aufzuweisen, und 1 verschloß das befallene Gefäß noch vollständig. 2 Thromben verschwanden ohne jegliche Therapie; 4 weitere unter Heparin- und/oder Phenprocoumonbehandlung.
    Notes: Summary Phlebography was carried out in a prospective randomised, controlled study during which dextran and small doses of s.c. heparin have been compared in general surgical and urological patients, in 31 persons with proven deep vein thrombosis diagnosed with the125I-fibrinogen test. In 16 out of the 31 patients a second phlebogram could be performed two weeks later. In this study all thrombi occurred intraoperatively. In 24 of the 31 patients, the appearance of thrombi was multilocular. Independent of the prevention instituted and irrespective of the therapy, the following phenomena could be seen 14 days after the first phlebogram: 9 thrombi retracted, 6 disappeared completely and 1 occluded the vein completely. 2 thrombi disappeared without any therapy whatsoever, the 4 others disappeared in patients receiving heparin and/or coumarin for treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468973
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  • 4
    Electronic Resource
    Electronic Resource
    Heat and mass transport in the photoacoustic effect on liquids (1991)
    Springer
    Applied physics 52 (1991), S. 223-233 
    Details
    ISSN: 1432-0630
    Keywords: 44.25 ; 44.60+f ; 47.25.Q
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The temperature oscillation accompanying the photoacoustic effect generates a periodic variation of the vapor pressure of a liquid. The propagation of the oscillating concentration of the vapor in the inert cell gas (air) is described by a mass diffusion wave on which a convective motion of the gas is superposed. The diffusion wave characterized by the diffusion coefficient of the cell gas alone can be measured by the Mirage effect, whereas a microphone detects the total mass flux including the convective flux, which increases with temperature. On approaching the boiling temperature, the convective flow will govern the oscillating transport of mass. The photoacoustic signal is determined directly from the flux of heat and mass at the boundary between liquid and gas using the Gauss' divergence theorem. We have found that the temperature behaviour of the amplitude and phase angle of the photoacoustic signal depends on the length of the gas column in the cell. The contribution of thermal expansion to the photoacoustic signal is considered using the composite piston model. The results of the calculations agree fairly well with the experimental data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00324582
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  • 5
    Electronic Resource
    Electronic Resource
    Withdrawal of a mumps vaccine: Reasons and impacts (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 387-388 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01955892
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  • 6
    Electronic Resource
    Electronic Resource
    Pertussis vaccines — 1993 (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 462-466 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01955049
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  • 7
    Electronic Resource
    Electronic Resource
    Thoughts of a reviewer (1990)
    Springer
    European journal of pediatrics 149 (1990), S. 822-824 
    Details
    ISSN: 1432-1076
    Keywords: Clinical studies ; Study design
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02072066
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of clonidine on sleep patterns in man (1977)
    Springer
    European journal of clinical pharmacology 12 (1977), S. 319-322 
    Details
    ISSN: 1432-1041
    Keywords: Clonidine ; Yohimbine ; sleep ; REM sleep
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Clonidine (300 µg orally) increased in man the total duration of sleep and strikingly reduced the duration of REM sleep. Yohimbine (10 mg per os) did not alter the sleep patterns in man but antagonized the effects of clonidine. These results provide evidence that an α sympathomimetic mechanism could suppress REM sleep and increased the total duration of sleep.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00562444
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  • 9
    Electronic Resource
    Electronic Resource
    Withdrawal of a mumps vaccine (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 467-468 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01983415
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  • 10
    Electronic Resource
    Electronic Resource
    Partial transtentorial displacement of the cerebellum and the brain stem in hydrocephalus — A primary condition or a result of treatment? (1976)
    Springer
    Acta neurochirurgica 33 (1976), S. 151-165 
    Details
    ISSN: 0942-0940
    Keywords: brain stem, cerebellum ; transtentorial displacement ; hydro-cephalus communicans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two oases of upward displacement of parts of the brain stem and the cerebellum are discussed. In both cases shunts for a hydrocephalus had been operating for a long time (three and a half years in one and seven months in the other). One infant had a meningomyelocele but no complete Arnold-Chiari malformation. The cause of the hydrocephalus in the other case was doubtful, but was thought to be transtentorial displacement of the brain stem and the cerebellum causing traction on the pons and consequent meningeal fibrosis with obstruction of the cisterna pontis. In this case osseous hypoplasia of the posterior fossa was excluded by craniometry, so the upward displacement must have been due to hypoplasia of the tentorium cerebelli and its low attachment to the occiput, bringing about a narrowing of the infratentorial space. The authors believe the condition to be a primary malformation, and reject the hypothesis of secondary herniation following long standing supratentorial decompression. The concept of a primary malformation is supported by previous descriptions of the condition in cases with spina bifida, Arnold-Chiari malformation, and hydrocephalus without shunting, as well as by other features in the cases which have been recorded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01886666
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