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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 10 (1968), S. 359-362 
    ISSN: 1432-0533
    Keywords: Monocytic cells of CNS ; Radioisotope labelling ; Blood cells entry into the CNS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Eintritt zirkulierender Blutzellen in das Gehirn wurde mittels radioaktiv markierter Zellen aus dem Knochenmark von Spender-auf Empfängertiere untersucht. Die Zellen wurden in vitro oder in vivo mittles H3-Thymidin oder H3-Uridin markiert. Die markierten Zellen vom Charakter der Monocyten oder Makrophagen dringen nach den erhobenen Befunden in normales Hirngewebe ein und sammeln sich in verschiedenartigen Hirnläsionen an. Es ergaben sich Hinweise dafür, daß diese Zellen später in die Milz zurückkehren.
    Notes: Summary The entry of circulating blood cells into the brain was studied by injecting radioactively labeled cells from the bone marrow of donor animals into recipient animals. The cells were labeledin vitro orin vivo, using H3 thymidine or H3 uridine. Labeled cells having features of monocytes or macrophages were shown to enter normal brain tissue and to aggregate at various types of brain lesions. There was indication that these cells later returned to the spleen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 10 (1968), S. 151-158 
    ISSN: 1432-0533
    Keywords: Corpus callosum ; Brain injury ; Traumatic lesion ; Marchiafava-Bignami-disease ; Demyelination ; Pressure of arteries
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Oberflächliche Balkenläsionen werden beschrieben, die bisher offensichtlich nicht im Schrifttum aufscheinen. Sie wurden in 17 von 168 laufend untersuchten Gehirnen angetroffen. Beziehungen zu klinischen Symptomen oder den Körperobduktionsbefunden lagen nicht vor. Die Morphologie und Beziehungen dieser Läsionen zu den Nachbarstrukturen lassen sie als eine Folge mechanischer Balkenschädigung interpretieren, doch ist ihr genauer Entstehungsmechanismus bisher ungeklärt.
    Notes: Summary Surface lesions of the corpus callosum, apparently hitherto unrecorded in the literature, are described. They were found in 17 cases among 168 consecutively examined brains. There was no correlation with clinical symptoms, or with general autopsy findings. Their morphology and relationship to neighboring structures suggest that they represent a form of physical trauma to the corpus callosum, but the exact mechanism of their production is not clear.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 15 (1968), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Atomic absorption spectroscopy was used for measuring the zinc content, in ppb (μg/1), of brain tissue. A new method for determining the correction factor of atomic absorption interference is described.Measurements of the zinc content of twenty-four regions of adult human brains showed the maximum zinc content in resistent sector and endplate of the Amnion's horn, corroborating the histochemical data. The distribution of zinc in other regions was relatively uniform, but white matter showed lower values than gray matter. The zinc content of seventeen regions of human newborn brains was below that in adult brains, for all regions. The blood content of brain tissue contributed only insignificantly to its zinc content.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 9 (1967), S. 126-135 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The existence of characteristic regional differences in the binding capacity of tissue for catecholamines was demonstrated by incubating sections of rat brain with tritiated norepinephrine or epinephrine or dopamine, and by radioautography. Microscopically, catecholamine binding occurred diffusely in the neuropil, or in pericellular aggregates upon nerve cells, in a pattern highly suggestive of synaptic buttons. A neuroanatomical account of the regional distribution patterns of norepinephrine binding in rat brain showed similarity to the known regional distribution of norepinephrine. However, there were quantitative and qualitative differences between the distribution of the binding mechanism and that of norepinephrine. Minor differences were found between the binding of norepinephrine and epinephrine; little binding occurred for dopamine. The binding mechanism was not facilitated by ATP, and was resistant to reserpine.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 79 (1967), S. 259-264 
    ISSN: 1432-0878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The observation that the myelin sheaths of human optic fibers seem to form first at the distal end of the tract with a progress of myelination toward the eye was tested by assays of cholesterol and cholesterol esters in segments of human optic nerves and tracts at various phases of development. It was found that the distal to proximal progress of myelination relates mainly to the fact that adult human optic fibers contain in their distal portion about twice the amount of cholesterol that occurs in the proximal portion. This gradient in cholesterol content along the fibers develops gradually in children. If the progress of cholesterol deposition is expressed as a percentage of the adult values, the proximo-distal differences are small, suggesting that myelination develops only slightly faster at the distal end.
    Type of Medium: Electronic Resource
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