ISSN:
1432-0428
Keywords:
Key words
;
Glucose
;
fructose
;
insulin
;
isolated fat cells
;
re-esterification of free fatty acids
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In isolated human fat cells of the greater omentum and the mammary gland, the effect of glucose, fructose, and/or insulin was tested on the re-esterification rate of FFA measured by the balance method. It could be shown that in the absence of glucose no re-esterification activity was demonstrable. Glucose alone or fructose alone stimulated the re-esterification of FFA dose-dependently in isolated fat cells of the greater omentum, and to a minor degree in fat cells of the mammary gland. Insulin had no effect on the re-esterification rate of FFA in the presence or absence of glucose or fructose, whereas it significantly stimulated the incorporation of glucose-C into CO2 and lipids. It is concluded that the re-esterification of FFA in human adipose tissue, at least in vitro, is mainly controlled by glucose without need for insulin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00461696
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