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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 21 (1975), S. 380-382 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0887-3585
    Keywords: bioactivity ; SK-hep-1 hepatoma ; interleukin-1 ; recombinant protein ; crystals ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The gene for human interleukin-1β was cloned from SK-hep-1 hepatoma cellular RNA and expressed at high levels in Escherichia coli both as the naturally processed form (rIL-1β) and as a variant with an additional sequence of three amino acids on the N-terminus (rIL-1β+). Expressed protein was purified to homogeneity by a sequence of steps, which included low pH incubation, adsorption and desorption from Procion Red Sepharose, sizing on a Superose 12 fast-performance liquid chromatography (FPLC) column, and anion exchange chromatography on QAE Sepharose. The final step provided a biologically active protein that migrates on twodimensional (2-D) gels as a single spot with a pI of 6.7 ± 0.2 and a molecular mass of 17,500 daltons. Concentrated solutions of rIL-1β have produced crystals by ammonium sulfate precipitation. The crystals are tetragonal, show the symmetry of space group P41 or its enantiomer, have lattice constants of a = 58.46 (1) and c = 77.02 (3) A, and scatter to at least 2 Å resolution. A structure determination based on these crystals is under way.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 18 (1994), S. 49-71 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: In this paper a coupled finite and boundary element formulation is developed for the analysis of excavation in jointed rock. The presence of joints in the rock mass has been included implicitly by treating it as an appropriate anisotropic elastic continuum. The boundary element formulation for an anisotropic medium is briefly discussed. Good agreement has been found between numerical and analytical solutions for several example problems, demonstrating the accuracy of the present formulation. Numerical solutions are also presented for the problems of a deep circular tunnel and a basement excavated in a variety of jointed rock masses.
    Additional Material: 20 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 17 (1993), S. 715-733 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: This paper critically examines the use of the modified Cam clay stress-strain model in predicting the thermomechanical behaviour of soft clays. The equations governing the thermomechanical behaviour of a saturated soil are summarized and their methods of solution are briefly discussed. The observed thermomechanical soil behaviour reported in the literature has been compared with the predictions made using the modified Cam clay model. In making these comparisons, two extensions of the well-known modified Cam clay model have been considered: one proposed by Britto et al.1 in which heating induces thermal stresses and strains in the soil but has no direct effect on the work hardening, and the other proposed by Hueckel and Borsetto2 in which a change in temperature also affects the yield surface. The comparisons are confined to the behaviour of normally and lightly overconsolidated clays, where the modified Cam clay is known to perform well. Apart from the effect of a single heating-cooling loop, cyclic behaviour is not considered. It is concluded that both models provide reasonable predictions under isotropic stress conditions. Although exhaustive comparisons have not been made for deviatoric stress excursions (because of the lack of experimental data), it appears from preliminary studies that neither model performs particularly well for this form of loading.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 18 (1994), S. 177-203 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: The problem of fully coupled consolidation and heat flow around a rigid cylindrical heat source buried in clay has been studied. The governing equations of the problem are summarized in the paper and a finite element time-marching scheme to obtain an approximate solution to the governing equations is described. The stress-strain behaviour of the skeleton of the saturated soil has been represented by both a linear elastic model and the modified Cam clay soil model. The results of a limited parametric study are presented with the aim of understanding the major mechanisms of soil behaviour close to buried canisters of hot radioactive waste. A range of soil properties has been included in the study, and the effects of soil disturbance during canister emplacement have also been considered.
    Additional Material: 19 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 18 (1994), S. 445-466 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: This paper presents a coupled, elastoplastic, finite element and boundary element method for the two-dimensional, non-linear analysis of anisotropic jointed rock. The non-linear and anisotropic behaviour of a jointed rock mass is simulated by representing the mass as an equivalent anisotropic, elastoplastic continuum, so that the influence of the jointing system is ‘smeared’ across the continuum, i.e. the individual joints are not modelled as discrete entities. Numerical examples have been solved to verify the capability, accuracy and efficiency of the present technique. The proposed technique has also been applied to the analysis of tunnel excavation problems in plane strain. The effects of anisotropy and non-linearity of the jointed rock mass during excavation have been investigated in some detail.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Improved measurement of δ13C values of n-alcohols and sterols by gas chromatography/isotope ratio mass spectrometry is shown after their derivatization to silyl ethers. A method of correcting for the effects of the added silyl carbon atoms on the measurements of the silylated derivatives is also described and an application of the method for providing information on the sources of lacustrine n-alcohols and sterols is given.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 12 (1968), S. 1751-1754 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The tensile and dynamic mechanical properties of poly(norbornene), prepared through ring-opening polymerization, were studied. Tensile strength and extensibility increased, while Young's modulus decreased with increasing molecular weight and with increasing content of trans relative to cis unsaturation. The damping factor Delta; was dependent on molecular weight only for the lower molecular weight samples. The out-of-phase modulus E″ and the damping factor decreased as the trans/cis ratio increased.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 12 (1978), S. 1-12 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The rotating ring-disk electrode technique has been applied to the study of anodic dissolution of dental amalgam in a simulated saline solution.The electroactive domains of the silver, tin, and mercury couples (the main constituents of the amalgam) were determined from current-potential curves obtained at a rotating gold-disk electrode in solutions containing salts of the respective metals. Subsequently, anodic currents were applied to a rotating amalgam-disk electrode and the soluble products produced were identified using a concentric gold ring electrode, i.e., using the rotating gold-ring, amalgam-disk electrode. Species generated at the amalgam disk are transferred to the gold ring by convective diffusion. Tin ions were found to be the only soluble species generated at the amalgam disk. No evidence for dissolution of other components was found. The selective dissolution of tin from the amalgam is also consistant with potential shifts observed in repetitive current-potential curves of an amalgam disk.This study provides a direct proof for the selective dissolution of tin during corrosion of dental amalgam in an in vitro environment.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 337-355 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: This investigation developed experimental evidence for the influence of different surface energy states on tissue incorporation of biomedical materials. Implants of two smooth metals, each with three different surface energy states, were placed in the subdermal fascial plane of the backs of New Zealand White rabbits and were allowed healing times of 10 and 20 days. The implant surfaces were thoroughly characterized by physical-chemical criteria prior to surgical placement and again following removal from the tissue capsules generated by the host animals. Quantitative histopathologic analysis, using standard morphometric criteria, of the adjacent tissues revealed up to a threefold increase of fibroblastic-fibrocytic cells against the initially scrupulously cleaned, high-surface-energy materials. The cells were flattened and active, producing tenacious bonds through a thin pre-adsorbed protein-dominated “conditioning” film, that could be broken only by cohesive failure in the tissue itself. In contrast, the lower-surface-energy materials typical of standard dental implants were “walled off” by a cell-poor, nonadhesive capsule with a fibrous interface separated from a thicker “conditioning” film by a lipid-rich mucus zone. The advantages of proper surface treatment to favor the desired degree of biological adhesion are apparent.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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