ISSN:
1573-2622
Schlagwort(e):
pattern electroretinogram
;
Fourier analysis
;
fovea
;
retinal eccentricity
;
spatial tuning
;
visual field
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract To investigate the value of the extrafoveal pattern electroretinogram for evaluation of local retinal defects, electroretinographic responses to contrast reversal stimulation were recorded at various locations in the central and midperipheral retina. Normal values were established in 20 eyes, and spatial selectivity at different retinal eccentricities was determined in four eyes. The response amplitude was found to decrease steeply from the fovea until about 12° eccentricity and to decline only slowly thereafter. For central stimulation a clear attenuation for coarser patterns was observed. At 20° and at 30° eccentricity the spatial tuning function exhibited a bandpass characteristic, with the maximum amplitude shifting to lower spatial frequencies. Despite the relatively low peripheral amplitudes a satisfactory signal to noise ratio of the second harmonic responses can be obtained by Fourier analysis, which improves clinical applicability. The comparison of sensitivity in the upper and lower retina revealed a considerable asymmetry, with responses in the upper retina approximately 20% higher. No significant difference, however, was found when the temporal or nasal retina was stimulated. The reproducibility of these results is high enough to encourage clinical studies. A case of retinal venous branch occlusion exemplifies the applicability of this technique in eccentric fundus lesions.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00154490
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