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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Transplant international 3 (1990), S. 176-180 
    ISSN: 1432-2277
    Keywords: T-cell repertoire ; Organ transplantation, T-cell repertoire ; Rejection, T-cell repertoire
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The immune repertoire of T lymphocytes invading human allografts is of fundamental importance both at the operational level, in order to achieve relevant matching, and at the functional level, since the unique capacity of T and B cells to specifically recognize allogeneic components restricts the origin of the signals leading to rejection by these cells. In this paper, the authors review their own work, as well as other contributions in this domain, with special reference to the frequency and function of donor-committed cells among the infiltrate and the relationship between T-cell receptor gene rearrangements and repertoire.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Gadolinium ; Kidney, benign tumours ; Kidney, cysts ; Kidney, MRI studies ; Kidney, neoplasms ; MRI, contrast enhancement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the value of T2-weighted and Gd-DOTA-enhanced T1-weighted images for the detection and characterisation of 33 small renal masses (14 clear cell carcinomas, 6 angiomyolipomas, 3 angiomyomas, 4 adenomas, 3 papillary carcinomas, 3 oncocytomas, 1 haemorrhagic cyst). Dynamic enhanced MRI was performed to study the tumoral vascular supply (19 cases). MRI depicted all the masses more than 1 cm in diameter, but missed all the lesions less than 1 cm (4 false-negative). The results of T2-weighted images and Gd-DOTA-enhanced images were similar as regards detection; however, Gd-DOTA-enhanced images depicted more clearly the tumours smaller than 2 cm (11 cases). MRI enabled the characterisation of only 3 masses (2 angiomyolipomas, 1 haemorrhagic cyst). New MRI features are described for oncocytomas (low signal intensity on T1-weighted images, high signal intensity on T2-weighted images, early and marked enhancement on dynamic enhanced MRI). Dynamic enhanced MRI did not contribute to the differentiation of benign from malignant tumours.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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