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  • Head space gas chromatography  (1)
  • Phenylglyoxylic acid  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 49 (1982), S. 325-339 
    ISSN: 1432-1246
    Keywords: Carbon felt dosimetry ; FRP boat production ; Mandelic acid ; Phenylglyoxylic acid ; Styrene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A survey on styrene exposure was conducted in five small to medium-sized fiber-reinforced plastic (FRP) boat plants utilizing carbon felt dosimeters as personal and stationary samplers to measure 4 h (TWA) exposure during workday afternoons. The heaviest exposure, up to 256 ppm by personal sampling and 174 ppm by stationary sampling, took place during the lamination on a mold to produce a boat shell, and the work inside narrow holds also resulted in exposures of a comparable degree. Styrene levels were much lower in other auxiliary works. The TWA of exposure in an entire boat production was estimated to be 40–50 ppm. Installation of several flexible hoses as an exhaust system was proved to be effective in decreasing the vapor concentration. Gas masks were also useful in reducing the exposure. Urine samples were collected from 96 male workers at the end of 8h work (4 h in the morning and 4 h in the afternoon) and also from 22 nonexposed male subjects, and analyzed for mandelic acid (MA), phenylglyoxylic acid (PhGA), and hippuric acid (HA). When the results of urinalyses were compared with 4-h styrene TWA as monitored by personal sampling, the best correlation was obtained with MA + PhGA/creatinine (the correlation coefficient, 0.88), followed by MA (0.84). For these two cases, regression lines and 95% confidence limits for the group means and for the individual values were calculated. The urinary levels of MA, PhGA, and HA in the 22 nonexposed male subjects were also tabulated.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1246
    Keywords: Biological monitoring ; Carbon felt dosimetry ; Head space gas chromatography ; Methyl ethyl ketone ; Urinalysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Head space gas chromatography (GC) was applied to measure methyl ethyl ketone (MEK) in urine from 62 MEK-exposed male workers, whose individual intensity of exposure to MEK was monitored utilizing the carbon felt dosimeter. The urinary MEK level increased rapidly to reach a plateau in the first quarter of the daily 8-h work, while very little MEK was detected in the preshift urine. When the MEK levels in the urine at the end of the shift were compared with the afternoon MEK-TWA values, the uncorrected MEK in urine correlated best with MEK in air (r=0.774, n=62), while correction for creatinine gave a comparable result and the correlation was poorer when corrected for a specific gravity of urine or for the lapse of time after preceding passage of urine. Balance of MEK absorption via inhalation and MEK excretion into urine revealed that only 0.1% of MEK absorbed will be excreted unchanged into urine. Wider application of head space GC is discussed for the analysis of unmetabolized solvents in urine.
    Type of Medium: Electronic Resource
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