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  • 1
    ISSN: 1432-069X
    Keywords: Mycosis fungoides ; Histopathology ; Benign inflammatory dermatoses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cutaneous infiltrate in mycosis fungoides (MF) is predominantly composed of T4-positive T-cells. Attempts to distinguish the early stages of this condition from benign inflammatory infiltrates using anti-T3, T4 and other T-cell-associated antibodies have hitherto been unsucessful. Recently a monoclonal antibody BE 2 has been described as selectively reacting against leukemic cells in patients with cutaneous T-cell lymphoma. To investigate whether the BE 2 antigen is differentially expressed in different stages of MF and benign dermatoses, thus facilitating diagnosis, especially of early MF, the reactivity of monoclonal antibody BE 2 against cutaneous infiltrates from such conditions was assessed. In the early stages of MF only a small number of reactive cells was present. In benign inflammatory infiltrates, especially in those that clinically and histologically were hardly distinguishable from early MF, BE 2 reactivity was essentially the same as in eczematous-stage MF. Lesions from plaque and tumor stage MF contained large numbers of BE 2-reactive cells. Our results indicate that expression of BE 2 is associated with the stage of a given MF lesion and is essentially identical in early MF and eczematous lesions with a similar histopathological appearance.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1394
    Keywords: Key words. Thermosphere models ; Non-gravitational forces ; Air drag ; Orbit determination ; Space geodesy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract. The Drag Temperature Model (1978) has been improved to respond better to the actual requirements of space geodesy, especially under extreme solar and geomagnetic conditions. Extended data and an improved algorithm have been considered, leading to valuable improvements. Temporal variations of temperature of the thermopause, total density and major chemical constituent density are reviewed and compared to the DTM94, DTM78 and MSIS86 models. A comparison with data is performed, giving the mean ratios between observed and model values with their root mean squares for different physical and geometric conditions. This comparison is made for the three models and includes data used in the modelling as well as external data. The limits of the thermosphere modelling are discussed.
    Type of Medium: Electronic Resource
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