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  • Inorganic Chemistry  (12)
  • cGMP-dependent protein kinase  (5)
  • Skinned coronary arteries  (2)
  • 1
    Electronic Resource
    Electronic Resource
    High-level expression of functional cGMP-dependent protein kinase using the baculovirus system
    Amsterdam : Elsevier
    FEBS Letters 336 (1993), S. 163-167 
    Details
    ISSN: 0014-5793
    Keywords: Baculovirus expression ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(93)81632-A
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  • 2
    Electronic Resource
    Electronic Resource
    cGMP-dependent protein kinase decreases calcium sensitivity of skinned cardiac fibers
    Amsterdam : Elsevier
    FEBS Letters 149 (1982), S. 171-175 
    Details
    ISSN: 0014-5793
    Keywords: Skinned cardiac muscle ; Troponin-I phosphorylation ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(82)81095-8
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  • 3
    Electronic Resource
    Electronic Resource
    Autophosphorylation of cGMP-dependent protein kinase is stimulated only by occupancy of one the two cGMP binding sites
    Amsterdam : Elsevier
    FEBS Letters 164 (1983), S. 350-354 
    Details
    ISSN: 0014-5793
    Keywords: 8-Benzyl-amino-cAMP ; Autophosphorylation ; N^2-Monobutyryl-c-GMP ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)80315-9
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  • 4
    Electronic Resource
    Electronic Resource
    Cyclic AMP-dependent protein kinase does not phosphorylate cyclic GMP-dependent protein kinase in vitro
    Amsterdam : Elsevier
    FEBS Letters 151 (1983), S. 71-75 
    Details
    ISSN: 0014-5793
    Keywords: Autophosphorylation ; Heat-stable inhibitor protein ; cAMP-dependent protein kinase ; cGMP-dependent protein kinase
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)80345-7
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  • 5
    Electronic Resource
    Electronic Resource
    Cyclic GMP-dependent protein kinase relaxes skinned fibers from guinea pig taemia coli but not from chicken gizzard (1986)
    Springer
    Pflügers Archiv 407 (1986), S. 87-91 
    Details
    ISSN: 1432-2013
    Keywords: cGMP ; cGMP-dependent protein kinase ; Cyclie nucleotides in skinned smooth muscle ; Skinned guinea pig taenia coli ; Skinned chicken gizzard
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of cGMP and cGMP-dependent protein kinase (cG-PK) on contraction and relaxation was studied in skinned smooth muscle fibers from guinea pig taenia coli and chicken gizzard. At a fixed [Ca2+] relaxation was significantly enhanced by activated cG-PK in fibers from guinea pig taenia coli, but not in those from chicken gizzard. The Ca2+-requirement for half maximal tension maintenance was shifted to the right. Relaxation was associated with a decline in phosphorylated myosin light chain-2 from 34% to 25%. Similarly to relaxation activated cG-PK inhibited tension development only in fibers from taenia coli. These results suggest that mammalian and chicken smooth muscle fibers respond differently to cG-PK.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00580726
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  • 6
    Electronic Resource
    Electronic Resource
    cGMP and cAMP inhibit tension development in skinned coronary arteries (1984)
    Springer
    Pflügers Archiv 401 (1984), S. 277-280 
    Details
    ISSN: 1432-2013
    Keywords: cGMP ; cAMP ; Skinned coronary arteries
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of physiological concentrations of cGMP and cAMP on tension development in skinned coronary arteries (Triton X-100) were studied. cGMP inhibited tension elicited at intermediate Ca2+ concentrations at pH 7.0 but not at more acidic or alkaline pH values. cAMP, on the other hand, decreased submaximal tension development independent of pH (from pH 6.5 to pH 7.2). Neither nucleotide affected tension development at maximally activating Ca2+ concentrations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00582596
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  • 7
    Electronic Resource
    Electronic Resource
    Relaxation of skinned coronary arteries depends on the relative concentrations of Ca2+, calmodulin and active cAMP-dependent protein kinase (1985)
    Springer
    Pflügers Archiv 405 (1985), S. 70-76 
    Details
    ISSN: 1432-2013
    Keywords: Skinned coronary arteries ; Smooth muscle ; Regulation of contractile tone ; cAMP-dependent protein kinase ; cAMP-dependent modulation of contractile tone ; Calmodulin ; Calcium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Maximally contracted detergent skinned coronary smooth muscle fibres are relaxed by lowering the concentration of free Ca2+. The extent and rate of relaxation depends on the concentration of free Ca2+ and calmodulin (CaM) suggesting that it is the Ca2+. CaM complex which is responsible for maintaining tension. At a fixed concentration of Ca2+ and CaM further relaxation can be achieved by addition of the catalytic subunit of the cAMP-dependent protein kinase (cAMP-kinase). The extent as well as the relaxation rate depend on the concentration of cAMP-kinase (0.01–0.5 μM) and both are antagonized by high concentrations of Ca2+ and CaM. The Ca2+-requirement for obtaining half maximal concentration is shifted from 1.1 μM to 6.3 μM Ca2+ in the presence of 0.5 μM cAMP-kinase. These data indicate that the response of the contractile apparatus to a change in the free [Ca2+] can be modulated by cAMP-kinase at the level of the contractile proteins. It is further suggested that the tone of coronary smooth muscle is determined by the relative and not by the absolute concentrations of Ca2+, CaM and cAMP-kinase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00591100
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  • 8
    Electronic Resource
    Electronic Resource
    Hydroxidgruppen an Zeolithen. II. Zahl und Eigenschaften von Hydroxidgruppen an CeNaY- und HNaY-Zeolithen unterschiedlichen Austauschgrades (1974)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 404 (1974), S. 142-160 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Hydroxide Groups on Zeolites. II. Number and Properties of Hydroxide Groups on CeNaY and HNaY Zeolites of Different Exchange DegreeThe number of hydroxide groups on CeNaY and HNaY zeolites was examined by D2 exchange, and their properties in dependence of the cation exchange degrees were studied by IR spectroscopy. On CeNaY zeolites there exist six kinds and on HNaY zeolites at least seven kinds of hydroxide groups.On the CeNaY zeolites, the hydroxide groups are produced by dissociative chemisorption of water on Ce3+ ions. Their total number increases continuously with increasing exchange degree. Some of the hydroxide groups are acid BRÖNSTED centers whose number increases with increasing exchange degree and decreases with the temperature of preheating increasing to about 600°C.On the HNaY zeolites, the hydroxide groups are produced by thermal decomposition of the NH+4 ions, by dealumination and interaction of the Al3+ ions produced in this way in the place of cations with water. Above the threshold value of 35% the total number of the hydroxide groups increases very rapidly with increasing exchange degree. One part of the hydroxide groups decreasing with increasing exchange degree acts as acid BRÖNSTED centers. The number of these centers does not decrease until at preheating temperatures above 450°C.
    Notes: An CeNaY- und HNaY-Zeolithen wurden durch D2-Austausch die Zahl und infrarotspektroskopisch die Eigenschaften der Hydroxidgruppen in Abhängigkeit vom Kationenaustauschgrad untersucht. Es existieren an CeNaY-sechs Arten und an HNaY-Zeolithen mindestens sieben Arten von Hydroxidgruppen.An den CeNaY-Zeolithen entstehen die Hydroxidgruppen durch dissoziative Chemisorption von Wasser an Ce3+-Ionen. Ihre Gesamtzahl wächst kontinuierlich mit steigendem Austauschgrad. Einige der Hydroxidgruppen sind saure BRÖNSTED-Zentren, deren Zahl mit steigendem Austauschgrad wächst und mit steigender Vorerhitzungstemperatur bis etwa 600°C sinkt.An den HNaY-Zeolithen entstehen die Hydroxidgruppen durch thermische Zersetzung der eingetauschten NH+4-Ionen und mit wachsendem Austauschgrad zunehmend durch das Herauslösen von Gitteraluminium und Wechselwirkung der so entstehenden Al3+-Ionen auf Kationenplätzen mit Wasser. Die Gesamtzahl der Hydroxidgruppen wächst oberhalb des Schwellenwertes von 35% sehr stark mit steigendem Austauschgrad an. Ein mit steigendem Austauschgrad abnehmender Anteil der Hydroxidgruppen wirkt als saure BRÖNSTED-Zentren, deren Zahl erst bei Vorerhitzungstemperaturen oberhalb von 450°C abnimmt.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19744040206
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  • 9
    Electronic Resource
    Electronic Resource
    Untersuchungen an oxidischen Katalysatoren. XXIX. Spektroskopische und katalytische Untersuchungen an Ni2+-, Co2+-, Cr3+- und Cu2+-ausgetauschten MordenitenProfessor Günther Rienäcker gewidmet (1979)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 452 (1979), S. 6-16 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Studies on Oxide Catalysts. XXIX. Spectroscopic and Catalytic Investigations on Ni2+-, Co2+-, Cr3+-, and Cu2+-exchanged MordenitesNiNaM, CoNaM, CrNaM und CuNaM (M = Mordenite) have been characterized by UV-VIS, EPR and i.r. spectroscopy and the results were compared with the catalytic activity and the activity-time-dependence in the cracking of n-octane and with the shape selectivity in the cracking of a n-octane and isooctane mixture. Water molecules acting as ligands of the exchanged cations are able to dissociate yielding Brönsted acidity. Brönsted sites may be regarded as catalytic active centers in the cracking reaction. Unreduced transition metal cations facilitate the “coking” of the mordenite.The unreduced chromium and cobalt cations for which a position within the main channel is expected, affect the diffusion of the branched paraffin molecule thus increasing shape selectivity.
    Notes: NiNaM, CoNaM, CrNaM und CuNaM (M = Mordenit) wurden durch UV-VIS-Spektroskopie, EPR- und IR-Untersuchungen charakterisiert und die erhaltenen Ergebnisse mit der katalytischen Aktivität und dem Aktivitäts-Zeit-Verhalten dieser Proben bei der Spaltung von n-Octan und der Formselektivität in der Spaltung eines Gemisches von n/iso-Octan verglichen. Wassermolekeln als Liganden der eingetauschten Kationen können dissoziieren und so einen Beitrag zur Brönsted-Acidität liefern. Die Brönsted-Zentren können als katalytisch aktive Zentren in der Spaltreaktion angesehen werden. Nichtreduzierte Übergangsmetallkationen vergrößern die Neigung des Mordenits zum „Verkoken“ wesentlich. Die nichtreduzierten Co2+- und Cr3+-Kationen, für die eine Position im Hauptkanal angenommen werden kann, wirken als zusätzliche Diffusionsbremse auf die verzweigte Paraffinmolekel und erhöhen die Formselektivität des Mordenits.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19794520103
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  • 10
    Electronic Resource
    Electronic Resource
    Untersuchungen an oxidischen Katalysatoren. XLII. Redoxverhalten des Nickels in NiNa—Y-Zeolithen 4. Einfluß der Zusammensetzung auf die Reduzierbarkeit von Nickel in NiNa—Y-Zeolithen (1985)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 521 (1985), S. 145-152 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Studies on Oxide Catalysts. XLii. Redox Behaviour of Nickel in Zeolites NiNa—Y. 4. Influence of Composition on the Reducibility of Nickel in Zeolites NiNa—YBy chemical analysis (reaction with K2Cr2O7) and ESCA investigations we determined the degree of reduction in reduced samples NiNa-Y as function of the mole ratio SiO2/Al2O3 (module), of the Ni2+ degree of exchange and the kind of the second cations. (NH4+, Ca2+, Co2+, and Nd3+) in the temperature region of 620-770 K. The degree of nickel reduction increases with increasing module, decreasing degree of exchange and decreasing number of Brönsted acidic centres. This behaviour is caused by the influence of the interaction between cations Ni2+ and zeolite lattice on the reduction equilibrium.
    Notes: Durch chemische Analyse (Reaktion mit K2Cr2O7) un ESCA-Untersuchungen wird in reduzierten NiNa—Y-Proben der Nickel-Reduktionsgrad als Funktion des SiO2/al2O3-Verhältnisses (Modul), des Nickelaustauschgrades und der Art eines Zweitkations (NH4+ +, Ca2+, Co2+, Nd3+) im Temperaturbereich von 620 - 770 K bestimmt. Der Nickel-Reduktionsgrad steigt mit wachsendem Modul, sinkendem Austauschgrad und sinkender Zahl Brönsted-acider Zentren. Die Ursache dafür wird in dem Einfluß der Ni2+-Zeolithgitter-Wechselwirkung auf das Reduktionsgleichgewicht gesehen.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19855210217
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