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  • 1
    Electronic Resource
    Electronic Resource
    Pre- and post-transplant assessment of liver function in paediatric liver transplantation (1992)
    Springer
    European journal of pediatrics 151 (1992), S. S39 
    Details
    ISSN: 1432-1076
    Keywords: Liver transplantation ; Liver function tests ; Prognostic tests
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The pre-operative risk of paediatric liver transplantation candidates (n=41) was assessed in a prospective study by means of clinical symptoms, conventional static and liver blood flow dependent dynamic liver function tests. Nine patients died during the 365-day waiting period. The data were subjected as covariates to a survival analysis in the Cox proportional hazards model. There was a significant relationsship between the results of mono-ethylglycinexylidide (MEGX) formation and ICG test and the 365-day survival rate. In the stepwise analysis, none of the remaining parameters improved the predictive ability when added to the dynamic liver function test results. The assessment of post-transplantation liver function was studied in 27 patients during the first 28 postoperative-day period. In addition, liver function was studied in a cross-sectional study 1–7 years after successful liver transplantation in children with complete or partial rehabilitation. In the early postoperative period severe organ damage was indicated by both static and dynamic liver function tests. In the later course after transplantation no deterioration of liver function measured with MEGX formation was to be observed. These findings demonstrate the usefulness of dynamic liver function tests in the pre- and post-transplant assessment of liver function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02125801
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Receiver operating characteristic (ROC) analysis of the ability of arterial ketone body ratio to predict graft outcome after liver transplantation — its sensitivity and specificity (1992)
    Springer
    Transplant international 5 (1992), S. 23-26 
    Details
    ISSN: 1432-2277
    Keywords: Liver transplantation ; graft prognosis test — Prognosis ; liver transplantation ; ketone body ratio — Arterial ketone body ratio ; prognosis liver graft
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To evaluate the ability of arterial ketone body ratio (AKBR; acetoacetate/3-hydroxybutyrate) to predict graft prognosis after liver transplantation, the diagnostic value as a predictive index was compared between AKBR and conventional liver function tests using receiver operating characteristic (ROC) analysis. The ROC curves were determined for AKBR, GOT, GPT, total bilirubin, serum lactate level, and prothrombin time, all of which were measured on the 1st and 2nd postoperative days in 88 cases of liver transplantation. Comparisons of the areas under the ROC curves between AKBR and other tests revealed the significant superiority of AKBR to other tests in predicting graft death within 1 month after transplantation. The present study suggests that AKBR can be used as an accurate index to predict graft prognosis after liver transplantation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00337185
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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