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  • Polymer and Materials Science  (10)
  • Endothelial cells  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Functional serotonin 5-HT1D receptors and 5-HT1Db receptor mRNA expression in human umbilical vein endothelial cells (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 352 (1995), S. 580-582 
    Details
    ISSN: 1432-1912
    Keywords: Key words 5-Hydroxytryptamine (5-HT ; serotonin) ; 5-HT1D receptors ; 5-HT1Dβ receptors ; Endothelial cells ; Cyclic AMP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pharmacological evidence has suggested the presence of 5-hydroxytryptamine (5-HT, serotonin), 5-HT1D receptors on endothelial cells but these receptors have never been identified unambiguously on this type of cells. We now report that human umbilical vein endothelial cells (HUVEC) express 5-HT1D receptors coupled to inhibition of cyclic AMP formation. 5-HT and the 5-HT1D receptor agonists 5-carboxamidotryptamine (5-CT) and sumatriptan were approximately equipotent at inhibiting forskolin-stimulated cyclic AMP accumulation in HUVEC (mean pEC50 7.6–8.2, maximal effect 30% inhibition). The 5-HT1A receptor agonist, 8-OH-DPAT was clearly less potent (pEC50 6.2) and less efficacious. The selective 5-HT1D receptor antagonist, GR127935 (1 nM) markedly inhibited the effect of 5-HT (apparent pKB 10.8). Reverse transcription-polymerase chain reaction analysis showed the mRNA for 5-HT1Dβ receptors to be expressed in HUVEC. These results demonstrate the presence of functional 5-HT1D receptors and the expression of 5-HT1Dβ receptor mRNA in HUVEC. They support the involvement of 5-HT1Dβ receptors in endothelial-mediated responses to 5-HT.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00169394
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  • 2
    Electronic Resource
    Electronic Resource
    Functional serotonin 5-HT1D receptors and 5-HT1Dβ receptor mRNA expression in human umbilical vein endothelial cells (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 352 (1995), S. 580-582 
    Details
    ISSN: 1432-1912
    Keywords: 5-Hydroxytryptamine (5-HT, serotonin) ; 5-HT1D receptors ; 5-HT1Dβ receptors ; Endothelial cells ; Cyclic AMP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pharmacological evidence has suggested the presence of 5-hydroxytryptamine (5-HT, serotonin), 5-HT1D receptors on endothelial cells but these receptors have never been identified unamiguously on this type of cells. We now report that human umbilical vein endothelial cells (HUVEC) express 5-HT1D receptors coupled to inhibitiion of cyclic AMP formatin. 5-HT and the 5-HT1D receptor agaonists 5-carboxamidotryptamine (5-CT) and sumatriptan were approximately equipotent at inhibiting forskolin-stimulated cyclic AMP accumulation in HUVEC (mean pEC50 7.6–8.2, maximal effect 30% inhibition). The 5-HT1A receptor agonist, 8-OH-DPAT was clearly less potent (pEC50 6.2) and less efficacious. The selective 5-HT1D receptor antagonist, GR127935 (1 nM) markedly inhibited the effct pf 5-HT (apparent pKB 10.8). Reverse transcription-polymerase chain reaction analysis showed the mRNA for 5-HT1Dβ receptors to be expressed in HUVEC. These results demonstrate the presence of functional 5-HT1D receptors and the expression of 5-HT1Dβreceptor mRNA in HUVEC. They support he involvement of 5-HT1Dβ receptors in endothelial-mediated responses to 5-HT.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00169394
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  • 3
    Electronic Resource
    Electronic Resource
    Korrosionsversuche an vernickelten Blechen aus beruhigtem und unberuhigtem StahlHerrn Dr. Heinrich Klas zum 60. Geburtstag gewidmet. (1960)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 11 (1960), S. 554-563 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Corrosion tests with nickel-plated sheets of killed and rimmed steelWith a number of different types of steel plates (killed and rimmed steel, Thomas steel, Siemens Martin steel, square steel), research has been carried out on the influence of the base metal on the effectiveness of the corrosion protection afforded by the galvanic nickel plating. With plates of the different types of steel subjected to the same finishing treatment, neither the short-time ferroxyle test nor the salt spray test nor storage under moist conditions revealed any noticeable differences in the corrosion resistance of the nickel plating. Minor differences between different types of plates, as they are sometimes observed with out door corrosion, were not noticeable with the short-time test.The investigations lead to the conclusion that, contrary to widespread opinion, killed steel can be nickel-plated with the same corrosion protection effect as rimmed steel.
    Notes: An verschiedenen Stahlblechsorten (beruhigter und unberuhigter Stahl, Th-, SM- und VK-Stahl) wurde der Einfluß des Grundmetalls auf den Rostschutzwert der galvanischen Vernicklung untersucht. Bei gleich vorgeschliffenen Blechen der verschiedenen Stahlsorten ergab die Kurzprüfung im Ferroxyltest, im Salzsprühversuch und bei der Feuchtlagerung keinen deutlichen Unterschied der Rostbeständigkeit der Vernicklung. Feinere Unterschiede, die bei der außenatmosphärischen Korrosion bei verschiedenen Blechsorten teilweise beobachtet wurden, ließen sich im Kurzversuch nicht feststellen.Auf Grund der durchgeführten Untersuchungen ist zu schließen, daß im Gegensatz zu einer verbreiteten Meinung beruhigter Stahl mit gleicher Rostbeständigkeit vernickelt werden kann wie unberuhigter.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19600110906
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of interfaces on the thermal degradation of polymer-metal compositesProd. No. 1458 (1967)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 11 (1967), S. 357-368 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Previous studies by Black and Blomquist on the degradative failure of polymer-metal adhesive bonds have shown that composite failure depends largely on the type of metal substrate employed. In the work reported herein, metal powders of high surface area have been employed to maximize the metal-polymer interface. The composite systems studied consisted for aluminum and iron with polycondensates of bisphenol A-diglycidyl ether, phenol-formaldehyde and poly-2,2′-(m-phenylene)-5,5′-bibenimidazole. The composites were prepared in the absence of air and thermally degraded in a time-of-flight mass spectrometer while the degradation products were continuously monitored from mass 1 to 200. In the polymer and polymer-metal systems investigated, iron accelerated the decomposition of all polymers studied. This was determined by plotting m/e against degradation temperature for the more common mass peaks such as hydrogen and carbon monoxide for the carbon-hydrogen-oxygen-containing polymer and hydrogen cyanide and ammonia for the carbon-hydrogen-nitrogen-containing polymer. This technique offers promise in determining the nature of the interface as well as the effect of the interface on polymer degradation.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1967.070110304
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  • 5
    Electronic Resource
    Electronic Resource
    Ozonisation du Polychlorure de Vinyle en Solution (1975)
    Weinheim : Wiley-Blackwell
    Angewandte Makromolekulare Chemie 47 (1975), S. 61-77 
    Details
    ISSN: 0003-3146
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: When the ozonisation of bulk or suspension poly(vinylchloride) is carried out in tetrachloroethane solution between 0-120°C the molecular weight decreases continuously and the rate of breaking of chains deduced from the intrinsic viscosity variation is constant under isothermal conditions. Whatever the time and temperature of ozonisation may be, at every breaking, β and α chlorinated acid groups are introduced which have been characterized by infrared spectroscopy, high resolution NMR spectroscopy and potentiometric titration in dimethylformamide. Besides these functions, peroxide groups have also been identified and their concentration has been determined for different times and temperatures of ozonisation.This study permits to propose two mechanisms to explain the breaking of chains. The first implies the previous dehydrochlorination of the polymer and the second the formation of unstable peroxides which by decomposition cause the breaking of chains.
    Notes: Quelle que soit la nature du polychlorure de vinyle (masse ou suspension) l'action de l'ozone en milieu homogène dans le tétrachloroéthane provoque la décroissance continue de la masse moléculaire dans le domaine de température 0-120°C et la vitesse de coupure des chaînes déduite des variations de viscosité est constante en conditions isothermes.Quels que soient le temps et la température d'ozonisation, à chaque point de coupure apparaissent des fonctions acides α et β chlorées qui ont été caractérisées par spectroscopie infra-rouge, RMN haute résolution et dosage potentiométrique en milieu diméthylformamide. Outre ces fonctions, des peroxydes ont égé également identifiés dans le polymère et on a suivi leur concentration en fonction des conditions d'ozonisation.Cette étude permet de proposer deux mécanismes pour expliquer la coupure des chaînes, l'un suppose une déhydrochloruration préalable du polymère et l'autre la formation de peroxydes instables qui en se décomposant provoqueraient la coupure des chaînes.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/apmc.1975.050470105
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  • 6
    Electronic Resource
    Electronic Resource
    Partielles schmelzen von verstrecktem polyäthylenWir danken der Firma Badische Anilin- und Sodafabrik AG, Ludwigshafen, für die Überlassung dieser Proben. (1969)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 127 (1969), S. 286-291 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1969.021270122
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  • 7
    Electronic Resource
    Electronic Resource
    Technologische Voraussetzungen für Mikrovisioplastische Untersuchungen (1994)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 25 (1994), S. 183-190 
    Details
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: The metal forming process is one of the complicates mechanical deformation process. Up to this time, the investigations are mainly directed to the macroscopically point of view. Metal forming models are based on continuum mechanical methods.In opposite to the continuum mechanical deformation theory is the physics of metals.It is the aim of the paper, to discuss the developed technical supposition for using the micro-visioplasticity, an new method of micro-grid application and results of micro-grid deformation using an upsetting press.
    Notes: Der Umformprozeß gehört zu den kompliziertesten Verformungsvorgängen. Bis heute wurden die meisten Untersuchungen mit makroskopischen Theorien durchgeführt. Viele der Umformtheorien basieren auf der Kontinuumsmechanik. Demgegenüber sind mikroskopisch betrachtet jedoch auch metallphysikalische Prozesse interessant.In der Arbeit werden deshalb eine Einrichtung zur Durchführung von Versuchen - die Mikrovisioplastizität nutzend - die Grundlagen und Methoden zur Herstellung von Mikrorastern sowie erste Versuchsergebnisse vorgestellt.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mawe.19940250505
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  • 8
    Electronic Resource
    Electronic Resource
    Verfahren zur Erstellung auswertbarer Bildvorlagen für mikrovisioplastische Untersuchungen (1996)
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 27 (1996), S. 287-296 
    Details
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: The mechanical properties of polycristalline materials are depent on the type, the combination and the orientation of the elements in the micro structure. By means of the method of Visioplasticity assumptions are currently realized to analyse kinematic parameters inside of single grains and grain groups. Strength of the free surface of the specimen will be rough by its plastical deformation, it was difficult to register the increments of deformation of the grid. By further development of a method of picture analysis it is also possible to reproduce a 3d-surface by utilization of single light microscopical pictures.
    Notes: Die mechanischen Eigenschaften polykristalliner Werkstoffe sind von der Art der Mikrostrukturelemente, deren Zusammenwirken und Orientierung hauptsächlich abhängig. Mittels der Methode der Visioplastizität werden gegenwärtig Voraussetzungen geschaffen, die die Analyse kinematischer Feldkenngrößen innerhalb einzelner Strukturelemente (Kristallite) und Strukturverbände gestattet. Aufgrund der verformungsbedingten Aufrauhung der freien Probenoberfläche traten Probleme bei der Aufnahme der Rasterverformungen auf. Über die Weiterentwicklung eines Verfahrens der Bildverarbeitung wurde es möglich, 3D-Oberflächenstrukturen anhand der Auswertung lichtmikroskopischer Einzelbildaufnahmen abzubilden.
    Additional Material: 25 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mawe.19960270607
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  • 9
    Electronic Resource
    Electronic Resource
    Determination of degree of crystallinity of drawn polymers by means of density measurements (1969)
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A-2: Polymer Physics 7 (1969), S. 37-45 
    Details
    ISSN: 0449-2978
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The well known procedure of determining the degree of crystallinity by means of measuring the density presupposes the knowledge of both the densities ρc and ρa of the crystalline and of the noncrystalline regions. By combination of small-angle and wide-angle x-ray scattering and of density measurements it can be shown that this method is not justified in the case of drawn polyethylene if the values of ρc and ρa known from isotropic material are used. Both ρc and ρa depend considerably on annealing and drawing conditions. In addition the effective density ρc* of the more densely packed phase in a two-phase structure is much lower than the value ρc calculated from the positions of the x-ray reflections due to a large number of lattice defects. This conclusion is based on the results of three independent sets of experiments: determination of the mean-square fluctuation of density 〈η2〉 by means of x-ray small-angle scattering; x-ray wide-angle measurements of the positions of the crystal reflections and of the halo arising from the noncrystalline regions; and comparison of densities and long periods of samples treated at various annealing temperatures.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1969.160070103
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  • 10
    Electronic Resource
    Electronic Resource
    Compressibility of lysozyme in solution from time-resolved Brillouin difference spectroscopyThis paper is dedicated to Dr. E. Lüscher on the occasion of his 60th birthday. (1985)
    New York : Wiley-Blackwell
    Biopolymers 24 (1985), S. 1543-1548 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360240810
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