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  • 1
    ISSN: 1432-1440
    Keywords: Niereninsuffizienz ; Diuretika ; Dyspnoe ; Ödeme ; Flüssigkeitsbilanz ; Hämofiltration ; Renal failure ; Diuretics ; Dyspnoea ; Oedema ; Fluid balance ; Haemofiltration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Fluid withdrawal in over-hydrated patients resistant to diuretics was obtained by means of a capillary haemofilter, using the arterio-venous pressure gradient for blood perfusion at a rate of 100 ml/min. The ultrafiltration rate was 200–600 ml/h and could be maintained as long as 48 h without changing the haemofilter. This method, which needs no technical investment, is easy and simple to handle for the physician, bears only a very low risk for the patient, and ensures a negative fluid balance even at a mean blood pressure of only 60 mm Hg.
    Notes: Zusammenfassung Unter Ausnutzung des arteriovenösen Blutdruckgradienten wurden überwässerte Patienten, bei denen eine Ausschwemmung mit Diuretika nicht mehr zu erreichen war, mit einem Kapillarhämofilter entwässert. Mit einer Blutperfusionsrate von 100 ml/min lag die Ultrafiltrationsrate bei 200–600 ml/h und konnte bis zu 48 h ohne Wechsel des Hämofilters aufrechterhalten werden. Der besondere Vorteil der arteriovenösen Hämofiltration liegt in der einfachen Handhabung für den Arzt und dem geringen Risiko für den Patienten im Vergleich zur maschinellen Hämofiltration. Eine technische Investition ist nicht erforderlich. Auch bei Blutdruckwerten um 60 mm Hg ist eine negative Flüssigkeitsbilanz möglich.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 59 (1981), S. 247-248 
    ISSN: 1432-1440
    Keywords: Myoglobin ; Renal failure ; Myocardial infarction ; Myoglobin ; Niereninsuffizienz ; Myokardinfarkt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 44 Patienten mit chronischer Niereninsuffizienz unterschiedlicher Äthiologie wurde das immunreaktive Serum-Myoglobin bestimmt und mit den Werten von Probanden mit normaler Nierenfunktion verglichen. Es fand sich — unabhängig von der Grunderkrankung — eine hoch signifikante lineare Korrelation zwischen dem Serum-Myoglobin und der Serum-Kreatinin-Konzentration. Bei Patienten mit Serum-Kreatinin-Werten über 550 µMol/1 (6,2 mg-%) lagen die Serum-Myoglobin Konzentrationen fast regelmäßig im pathologischen Bereich. Dies gilt auch für chronische Dialysepatienten. Die Befunde zeigen, daß bei Patienten mit höhergradiger, chronischer Niereninsuffizienz das Serum-Myoglobin nur mit Einschränkung zur Infarktdiagnostik geeignet ist.
    Notes: Summary In 44 patients with chronic renal failure of varied etiology serum immunoreactive myoglobin was measured and compared to values obtained in patients with normal renal function. Irrespective of the underlying disease a highly significant linear correlation was found between serum immunoreactive myoglobin and serum creatinine concentration. In patients with serum creatinine concentrations above 550 µmol/1 (6.2 mg%) serum myoglobin was as a rule elevated above the range found in the controls with normal renal function. This was also true in dialysis patients. These result demonstrate that serum myoglobin may only be used with restrictions in the diagnosis of myocardial infarction in patients suffering from advanced chronic renal failure.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1440
    Keywords: L-Carnitine ; Renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The influence of age, sex, and renal function on serum levels and urinary excretion of free carnitine was studied in 187 subjects. Sixty-one subjects with normal renal function (creatinine clearance 〉100 ml/min) showed a serum carnitine level of 72.2±23.2 µmol/l. The carnitine values of males (76.8±23.3 µmol/l,n=39) were higher (p〈0.05) than those of females (64.0±21.0 µmol/l, n=22). Carnitine levels did not correlate with age. Values in patients with normal renal function did not differ from serum carnitine levels in healthy controls (74.7±17.5 µmol/l,n=49). The mean urinary carnitine excretion per day was 163.5 µmol (range 63.7–419.6 µmol) in patients with intact renal function. Extreme impairment of glomerular filtration rate (creatinine clearance 〈20 ml/min) resulted in higher carnitine concentrations in serum (108.9±39.4 µmol/l,n=18,p〈0.05), lower carnitine elimination per day (78.5 µmol, range 14.5–424.3 µmol,n=18,p〈0.05) and a decreased carnitine clearance (0.8 ml/min, range 0.2–3.8 ml/min). These data together with earlier results obtained in dialysis patients suggest that carnitine metabolism in renal failure is altered by reduction of both endogenous carnitine biosynthesis and renal carnitine clearance.
    Type of Medium: Electronic Resource
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