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  • 1
    Digitale Medien
    Digitale Medien
    The intracellular pH of tunicate blood cells: Ascidia ceratodes whole blood, morula cells, vacuoles and cytoplasm
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/General Subjects 1033 (1990), S. 311-317 
    Details
    ISSN: 0304-4165
    Schlagwort(e): (A. ceratodes) ; 5,5-Dimethyloxazolidine-2,4-dione ; Tunicate ; Vanadium ; pH, intracellular
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Medizin , Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0304-4165(90)90139-N
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  • 2
    Digitale Medien
    Digitale Medien
    Acetabular labral tears: contrast-enhanced MR imaging under continuous leg traction (1996)
    Springer
    Skeletal radiology 25 (1996), S. 349-356 
    Details
    ISSN: 1432-2161
    Schlagwort(e): Key words Acetabular labrum ; Magnetic resonance imaging ; hip ; Gadolinium ; Traction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Objective. The objective of this study was to evaluate the effects of continuous leg traction on contrast-enhanced MR imaging of the hip joint and to determine whether MR imaging under these conditions is useful for demonstrating acetabular labral tears. Design and patients. Nineteen hips underwent MR imaging with a T1-weighted spin-echo sequence, followed by MR imaging under continuous leg traction after intravenous injection of gadolinium-DTPA. Joint fluid enhancement and labral contour detection were evaluated. Eleven hips had labral tears shown by conventional arthrography, arthroscopy and macroscopic surgical findings. Assessment of labral tears by MR imaging was correlated with the diagnosis based on these standard techniques. Results and conclusions. Joint fluid enhancement was obtained in all hips at 30 min after injection. Superior and inferior labral surfaces were completely delineated in 1 hip on the unenhanced MR images, and in 7 and 13 hips, respectively, on the enhanced images under traction. The enhanced images under traction depicted 9 of the 11 labral tears. Comparison between the unenhanced image and the enhanced image under traction avoided mistaking undercutting of the labrum for a tear in 4 hips. Contrast-enhanced MR imaging under traction was valuable for detecting labral tears non-invasively and without radiation. Follow-up examinations using this method in patients with acetabular dysplasia can help to clarify the natural course of labral disorders and enable better treatment planning.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002560050094
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  • 3
    Digitale Medien
    Digitale Medien
    MR arthrography of elbow: evaluation of the ulnar collateral ligament of elbow (1996)
    Springer
    Skeletal radiology 25 (1996), S. 629-634 
    Details
    ISSN: 1432-2161
    Schlagwort(e): Key words Elbow ; Ulnar collateral ligament ; Magnetic resonance imaging
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Objective. The purpose of this study was to evaluate ulnar collateral ligament (UCL) injury of the elbow in throwing athletes by MRI and MR arthrography. Design. Ten elbows of throwing athletes were examined on both plain MRI and MR saline arthrography and the injuries subsequently surgically proven. Spin-echo (SE) T1-weighted and fast SE T2-weighted coronal images were obtained. Results. The UCL was unclear in all ten cases on T1-weighted MRI. In five cases an avulsion fracture was also found on T1-weighted MRI. On T2-weighted MRI, abnormal high-intensity areas were identified in or around the UCL. On T2-weighted MR arthrography images, extracapsular high-intensity areas, which represent extracapsular leakage, were found in four of five cases with avulsion fracture. At surgery, all these four cases showed avulsion fractures with instability; the other case had a fracture but it was stable and adherent to the humerus. On T2-weighted MR arthrography images, an extracapsular high-intensity area was found in one of the five cases without avulsion fracture. At surgery this patient had a complete tear of the UCL itself. Conclusion. MR arthrography provided additional information for evaluating the degree of UCL injury.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002560050149
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  • 4
    Digitale Medien
    Digitale Medien
    Intracellular application of polyamine and polyamine amide inhibits the quisqualate-sensitive ionotropic glutamate receptor of locust (Schistocerca gregaria) muscle (1997)
    Springer
    Invertebrate neuroscience 2 (1997), S. 223-233 
    Details
    ISSN: 1439-1104
    Schlagwort(e): philanthotoxins ; patch clamp ; locust muscle ; ionotropic glutamate receptor ; intracellular injection
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The effects of intracellularly-applied philanthotoxin-343 (PhTX-343) on single channel currents gated by quisqualate-sensitive glutamate receptors (qGluR) of locust leg muscle have been studied. PhTX-343 initially increased qGluR channel open probability, mainly by virtue of an increase in mean channel open time, but this was followed by a decrease in channel open probability, sometimes to zero, because of a decline in the frequency of channel openings and a decline in mean channel open time. These results suggest that antagonism of qGluR by PhTX-343 can arise, in part, through binding of the toxin to a site or sites on the intracellular domain of this receptor.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02211935
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  • 5
    Digitale Medien
    Digitale Medien
    The action of philanthotoxin-343 and photolabile analogues on locust (Schistocerca gregaria) muscle (1995)
    Springer
    Invertebrate neuroscience 1 (1995), S. 159-172 
    Details
    ISSN: 1439-1104
    Schlagwort(e): glutamate receptors ; locust muscle ; photolabile philanthotoxins ; voltage clamp ; patch clamp
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The effects of philanthotoxin-343 (PhTX-343; tyrosyl-butanoyl-spermine) and photolabile analogues of this synthetic toxin on locust (Schistocerca gregaria) skeletal muscle have been investigated using whole muscle preparations (twitch contractions), single muscle fibres (excitatory postsynaptic currents (EPSCs)) and muscle membrane patches containing single quisqualate-sensitive glutamate receptors (qGluR). Analogues containing an azido group attached to either the butanoyl side-chain of PhTX-343 or as a substitute for the hydroxyl moiety of the tyrosyl residue were about 6 fold more potent antagonists than PhTX-343; those with an azido group located at the distal end of the toxin molecule were generally 2–3 fold less potent than PhTX-343. When these compounds were tested in subdued light, they were reversible antagonists of the muscle twitch, EPSC and qGluR. When a muscle was irradiated with U.V. during application of photolabile toxin combined with either neural stimulation of the muscle orl-glutamate application, antagonism of the twitch, EPSC and qGluR was complete and irreversible.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02331913
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