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  • vascular dementia of the Binswanger type  (4)
  • Polymer and Materials Science  (3)
  • Anterior choroidal artery  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The urate and xanthine concentrations in the cerebrospinal fluid in patients with vascular dementia of the Binswanger type, Alzheimer type dementia, and Parkinson's disease (1993)
    Springer
    Journal of neural transmission 6 (1993), S. 119-126 
    Details
    ISSN: 1435-1463
    Keywords: Urate ; xanthine ; vascular dementia of the Binswanger type ; Alzheimer type dementia ; Parkinson's disease ; cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We determined the urate and xanthine concentrations in the cerebrospinal fluid (CSF) in patients with vascular dementia of the Binswanger type (VDBT), Alzheimer type dementia (ATD), and Parkinson's disease (PD). We found that the urate concentration was significantly increased in VDBT patients, but significantly decreased in ATD patients compared with controls. The ratio of the concentrations of uric acid (UCSF) to xanthine (XCSF) in the CSF (UCSF/XCSF) had a significant correlation with the ratio of the UCSF to the urate concentration in serum (Userum) (UCSF/Userum) in ATD and PD, whereas UCSF/Userum increased independently of UCSF/XCSF in VDBT. We concluded that the significant increase in the urate concentration in VDBT is mainly due to an impairment of the blood-brain barrier (BBB), and its significant reduction in ATD may reflect impaired brain metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02261005
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  • 2
    Electronic Resource
    Electronic Resource
    Retrograde filling of the anterior choroidal artery: vertebral angiographic sign of obstruction in the carotid system (1992)
    Springer
    Neuroradiology 34 (1992), S. 504-507 
    Details
    ISSN: 1432-1920
    Keywords: Cerebral angiography ; Collateral circulation ; Anterior choroidal artery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Retrograde filling of seven anterior choroidal arteries from the posterior circulation was observed on a vertebral angiogram in six patients with occlusion of the proximal anterior choroidal artery or of the internal carotid artery. In one patient with thrombotic occlusion of the internal carotid artery, the enlarged anterior choroidal artery functioned as a major collateral pathway from the posterior circulation to the territory of the middle cerebral artery. Retrograde filling of the anterior choroidal artery is a sign of obstruction changes in the ipsilateral carotid artery at or proximal to the origin of the anterior choroidal artery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00598961
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  • 3
    Electronic Resource
    Electronic Resource
    The anterior choroidal artery syndrome (1994)
    Springer
    Neuroradiology 36 (1994), S. 337-339 
    Details
    ISSN: 1432-1920
    Keywords: Microangiography ; Anterior choroidal artery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distribution of the anterior choroidal artery (AChA) was analysed on coronal, sagittal and axial microangiograms of cadaver brains. On axial sections, the territory of the AChA was confirned to an arcuate zone between the striatum anterolaterally and the thalamus posteromedially. On sagittal sections, fine vessels from the cisternal part of the AChA were seen to extend upwards and somewhat posteriorly into the region of the posterior limb of the internal capsule. On coronal sections, ascending branches of the AChA coursed latcrally and then upwards to penetrate the globus pallidus and the inferior portion of the posterior limb of the internal capsule, apparently terminating at the lateral border of the thalamus. Determining the distribution of this artery on multiplanar sections was helpful for interpreting pathological changes, including infarcts, occurring in this region on multiplanar CT and/or MR images.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00612113
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  • 4
    Electronic Resource
    Electronic Resource
    Cerebrospinal fluid acetylcholine and choline in vascular dementia of Binswanger and multiple small infarct types as compared with Alzheimer-type dementia (1996)
    Springer
    Journal of neural transmission 103 (1996), S. 1211-1220 
    Details
    ISSN: 1435-1463
    Keywords: Acetylcholine ; choline ; cerebrospinal fluid ; Alzheimer-type dementia ; vascular dementia of the Binswanger type ; multi-infarct dementia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The acetylcholine (ACh) and choline (Ch) concentrations in the cerebrospinal fluid were investigated in patients with vascular dementia of the Binswanger type (VDBT) or multiple small infarct type (MSID) as compared with patients with Alzheimer-type dementia (ATD). The ACh concentration in patients with ATD was found to be significantly lower than in controls (73%, p 〈 0.0001), and showed a significant positive correlation with dementia scale scores (rs=0.63, p 〈 0.03). The Ch concentration in the CSF of ATD patients was approximately the same as in controls. In VDBT/MSID patients, the ACh concentration was significantly lower than in controls (p 〈 0.001), also showing a significant positive correlation with dementia scale scores (rs=0.62, p 〈 0.02), but was significantly higher than in ATD patients (p 〈 0.001). Moreover, the Ch concentration in VDBT/MSID patients was significantly higher than in controls (p 〈 0.001) or ATD patients (p 〈 0.001). These results suggest that simultaneous determination of ACh and Ch concentrations in CSF may be useful for differentiating VDBT/MSID from ATD and that increasing the ACh level using cholinergic agents may be a beneficial therapeutic strategy for the treatment of ATD as well as VDBT/MSIT, and is worthy of further investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01271206
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  • 5
    Electronic Resource
    Electronic Resource
    Concentration of monoamines and their metabolites in the cerebrospinal fluid from patients with senile dementia of the Alzheimer type and vascular dementia of the Binswanger type (1992)
    Springer
    Journal of neural transmission 4 (1992), S. 69-77 
    Details
    ISSN: 1435-1463
    Keywords: Dopamine ; norepinephrine ; cerebrospinal fluid ; senile dementia of the Alzheimer type ; vascular dementia of the Binswanger type
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We measured the concentrations of total (conjugated and unconjugated) monoamines (dopamine, DA; norepinephrine, NE) and monoamine metabolites (homovanillic acid, HVA; 3-methoxy-4-hydroxyphenyleneglycol, MHPG; 5-hydroxyindoleacetic acid, 5-HIAA) in the cerebrospinal fluid (CSF), using HPLC-ECD in 11 patients with Alzheimer's disease (AD) or senile dementia of the Alzheimer type (SDAT), 17 patients with vascular dementia of the Binswanger type (VDBT), and 15 controls. In AD/SDAT, there was a significant decrease in the DA concentration and a significant increase in the MHPG concentration. The average NE concentration was not altered, but significantly increased with the progression of intellectual disability. There were no significant changes in HVA and 5-HIAA concentrations. Patients with VDBT showed a significant increase in the DA concentration and a significant decrease in HVA and 5-HIAA concentrations. The DA concentrations increased significantly with the progression of dementia and ventricular enlargement. These results indicate that the noradrenergic and dopaminergic system in particular are altered in AD/SDAT, while the dopaminergic and serotonergic systems are mainly involved in VDBT.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02257623
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  • 6
    Electronic Resource
    Electronic Resource
    Indoleamine concentrations in cerebrospinal fluid from patients with Alzheimer type and Binswanger type dementias before and after administration of citalopram, a synthetic serotonin uptake inhibitor (1995)
    Springer
    Journal of neural transmission 9 (1995), S. 121-131 
    Details
    ISSN: 1435-1463
    Keywords: Alzheimer type dementia ; vascular dementia of the Binswanger type ; serotonin ; kynurenine ; citalopram ; cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied changes in the concentrations of serotonin (5-HT), kynurenine, and other indoleamines in the cerebrospinal fluid of patients with Alzheimer type dementia (ATD) and those with Binswanger type vascular dementia (VDBT), and changes in these indoleamine concentrations 2 weeks after administration of citalopram, a 5-HT uptake inhibitor. The concentrations of total 5-HT (p〈0.005) and kynurenine (p〈0.005) were significantly decreased in ATD patients in comparison to those of the controls. After citalopram administration, there was a remarkable increase in 5-HT concentration (249%, p〈0.0001) and a significant decrease in 5-HIAA concentration (22%, p〈0.02). In the VDBT patients, only 5-HT showed a significant decrease (p〈0.005) in comparison to the control values. It also increased significantly (214%) after citalopram administration. The 5-HT/tryptophan and kynurenine/tryptophan ratios were not correlated for the controls, but did significantly for the ATD and VDBT patients; after citalopram treatment, the increase in 5-HT/tryptophan was correlated significantly with that of kynurenine/tryptophan for ATD, but not for VDBT. These results suggest that both the serotonin and kynurenine pathways are impaired in ATD; whereas, the serotonin pathway alone is in VDBT, and that these impairments are ameliorated by the administration of citalopram.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02259654
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  • 7
    Electronic Resource
    Electronic Resource
    Studies of poly-yne polymers containing transition metals in the main chain. 5. A design of metal arrangement in polymer backbone (1980)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 18 (1980), S. 349-353 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1980.170180135
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  • 8
    Electronic Resource
    Electronic Resource
    Studies on polyyne polymers containing transition metals in the main chain. VII. Synthesis and characterization of palladium-polyyne polymers (1982)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 20 (1982), S. 565-573 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Metal-polyyne polymers consisting of palladium and conjugated acetylenic systems, where PD and R represent the  - Pd(PBu3)2 - moiety and alkyl groups, respectively, were prepared by polycondensation between palladium chlorides and α,ω-diethynyl compounds in amines using a catalytic amount of cuprous iodide. The molecular weights of the polymers formed were greatly affected by the basicity of the amines and the addition of free phosphines to the polymerization system. Under the optimum conditions, i.e., in the presence of CuI and PBu3 (in molar ratio 1/4) in piperidine at room temperature, polymer Ia (R1 = R2 = H) having M̄w = 29,000 was obtained.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1982.170200230
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  • 9
    Electronic Resource
    Electronic Resource
    Studies on polyyne polymers containing transition metals in the main chain. IV. Polymer synthesis by oxidative coupling of transition metal-bis(acetylide) complexes (1980)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 18 (1980), S. 661-669 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The metal-polyyne polymers consisting of transition metals and conjugated tetrayne systems where M represents —Pt(PBu3)2— or —Pd(PBu3)2— moiety were prepared by the oxidative coupling method and characterized by spectral analysis, associated with novel depolymerization giving binuclear transition metal complexes, and
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1980.170180224
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