ISSN:
1089-7623
Source:
AIP Digital Archive
Topics:
Physics
,
Electrical Engineering, Measurement and Control Technology
Notes:
Laser desorption studies often require the visualization of an ultraviolet laser source on a metallic surface for the purpose of irradiating a specific surface site and for repositioning the laser source to other surface sites. In some laser desorption techniques, for example, matrix assisted laser desorption ionization, the highest ionization efficiency for biological samples, is obtained at or near the ablation threshold (106 W/cm2) of the ultraviolet-absorbing organic matrix. At these low laser intensities, the laser beam footprint is difficult to observe on the sample or the surrounding support surface. To aid this visualization, we have used anodization to incorporate a fluorescent dye into the surface oxide layer of aluminum. The result is a hard, chemically noncontaminating, intensely fluorescent sample support surface for laser desorption investigations. © 1995 American Institute of Physics.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1063/1.1146057
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