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  • 1995-1999  (25)
  • 1985-1989  (18)
  • 1915-1919  (1)
  • 1900-1904  (2)
  • 11
    Electronic Resource
    Electronic Resource
    Antiallergic activity of loratadine, a non-sedating antihistamine (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 42 (1987), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Loratadine is a new non-sedating antihistamine. The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction. In addition, the two antihistamines were evaluated in models of immunologically mediated allergic reactions. Loratadine is a more potent inhibitor of histamine-induced bronchospasm in guinea pigs than is terfenadine. Both antihistamines exhibit marked antiserotonin activity at doses 10 times their antihistamine ED50 values. In contrast, loratadine and terfenadine produce little or no inhibition of the bronchial responses to methacholine, leukotriene C4 or platelet-activating factor. An allergic bronchospasm in guinea pigs is inhibited by loratadine (ED50= 0.40 mg/kg, p.o.) and terfenadine (ED50= 1.7 mg/kg, p.o.). The bronchospasm associated with allergic anaphylaxis in rats is significantly inhibited by 10 mg/kg, p.o. loratadine and 30 mg/kg, p.o. terfenadine. Loratadine exhibits antiallergy activity in vitro. At micromolar concentrations, loratadine inhibits the release of histamine from Con A and A23187-stimulated rat peritoneal mast cells and the release of histamine and leukotrine C4 from a Con A-stimulated cloned murine mast cell line
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1987.tb02188.x
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  • 12
    Electronic Resource
    Electronic Resource
    The incidence of Fusarium moniliforme on maize from Central America, Africa and Asia during 1992–1995 (1997)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Plant pathology 46 (1997), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Samples of maize seed were obtained from countries in Central America, Africa and Asia and assessed for fungal infection. Fusarium spp. were the largest single group of fungi present, and from these Fusarium moniliforme was the species most frequently isolated. Other fungi, including Stenocarpella (Diplodia) maydis, S. macrospora and Acremonium strictum, were also present in significant numbers. Isolates of F. moniliforme were characterized for mating populations, using RAPDs, and a number of isolates, taken at random from those assigned to specific mating groups, were also confirmed by crossing. Isolates were also characterized for fusaric acid production and significant differences in fusaric acid production were detected between isolates from different countries and regions within countries. A detailed analysis of isolates from one country, Kenya, was undertaken. The importance of the pathogens is discussed in relation to human, animal and seed health and quarantine regulations, and plant breeding objectives.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3059.1997.d01-200.x
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  • 13
    Electronic Resource
    Electronic Resource
    Reflux symptom relief with omeprazole in patients without unequivocal oesophagitis (1996)
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 10 (1996), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: As many as 50% of patients with reflux symptoms have no endoscopic evidence of oesophagitis. This multicentre study was designed to assess symptom relief after omeprazole 20 mg once daily in patients with symptoms typical of gastro-oesophageal reflux disease but without endoscopic evidence of oesophagitis. Methods: Patients (n=209) were randomized in a double-blind study to receive either omeprazole 20 mg once daily (n=98) or placebo (n=111) for 4 weeks. Symptoms were assessed at clinic visits and using daily diary cards, with patient-completed questionnaires providing additional data on symptoms and on psychological disturbance. Results: On completion, symptom relief favoured omeprazole: 57% of patients on omeprazole were free of heartburn (vs. 19% on placebo), 75% were free of regurgitation (47%) and 43% were completely asymptomatic (14%), each with P〈0.0001. Fewer patients in the omeprazole group required alginate/antacid relief medication (P〈0.05). Symptom relief (time to first heartburn-free day) was more rapid with omeprazole (2 vs. 5 days on placebo; P〈0.01). A greater reduction in anxiety occurred in the omeprazole group (P〈0.05). Conclusion: Omeprazole 20 mg once daily is effective in providing relief of the symptoms typical of gastro-oesophageal reflux disease in patients with essentially normal oesophageal mucosa.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1996.44186000.x
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  • 14
    Electronic Resource
    Electronic Resource
    Review article: the management of primary sclerosing cholangitis (1997)
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by a progressive obliterating fibrosis of the intrahepatic and extrahepatic bile ducts. The pathogenesis of PSC is poorly understood but it is thought to be an immune-mediated disease. The optimal therapy which successfully improves symptoms, delays progression towards liver failure and transplantation and prevents the onset of cholangiocarcinoma remains elusive. Although current treatments are used to manage cholestasis and its consequences and some of the more general complications of the disease, none of the current therapeutic agents have been shown to retard and reverse the rate of disease progression. The role of cupruretics, corticosteroids, methotrexate, anti-fibrogenic agents and ursodeoxycholic acid in the treatment of PSC is reviewed. Orthotopic liver transplantation remains the only therapeutic option for advanced PSC but the timing of transplantation remains controversial and the possibility of recurrence of the disease in the graft is increasingly recognised. It is likely that greater insight into the pathogenetic mechanisms involved in PSC will allow therapy to be targetted more specifically at the biliary epithelium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1997.91263000.x
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  • 15
    Electronic Resource
    Electronic Resource
    Demonstration of Strain-hardening of Steel (1915)
    [s.l.] : Nature Publishing Group
    Nature 94 (1915), S. 589-589 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE accompanying photograph (Fig. 1) represents the side of a steel bar. The bar was first marked by a punch in the way shown, and the punch marks were afterwards completely filed out. The side was then polished and the bar pulled in a testing machine beyond the elastic limit of the material. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/094589c0
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  • 16
    Electronic Resource
    Electronic Resource
    Gamma-spectroscopy of the 199At nucleus with the Recoil Filter Detector (1998)
    Springer
    The European physical journal 3 (1998), S. 311-312 
    Details
    ISSN: 1434-601X
    Keywords: PACS:23.20.Lv Gamma transitions and level energies – 27.80.+w 190 ≤ A ≤ 219 – 29.40.Ym Other detectors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The neutron deficient 199At nucleus has been studied in the 175Lu+28Si reaction at Eb= 141 MeV. In order to select events of interest in the presence of the very strong background caused by fission, γ-rays have been detected in coincidence with recoiling evaporation residues. The excited states of 199At observed for the first time may indicate that this nucleus is deformed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500050184
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  • 17
    Electronic Resource
    Electronic Resource
    Use of the64Ni(36S,34Si)66Zn reaction to measure the mass of34Si (1985)
    Springer
    The European physical journal 321 (1985), S. 119-123 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The reaction64Ni(36S,34Si)66Zn atE=198 MeV has been used to measure the mass excess of34Si; a value of −19.971 −0.044 +0.037 MeV was obtained. This result which is in agreement with the previous value (−19.85±0.30 MeV) is in excellent agreement with recent shell-model mass predictions. The result is discussed within the context of the proposed region of deformation aroundZ=11,N=20.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01411955
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  • 18
    Electronic Resource
    Electronic Resource
    The observation of a superdeformed structure in82Y (1995)
    Springer
    The European physical journal 353 (1995), S. 251-253 
    Details
    ISSN: 1434-601X
    Keywords: 21.10.Re ; 21.60.Cs ; 23.20.Lv ; 27.50.+e
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The58Ni(30Si,αpn)82Y reaction at a beam energy of 134 MeV was used to populate the odd-odd nucleus82Y and coincidentγ rays depopulating high spin states in the evaporation residues were detected with the EUROGAM Phase 2 array. A superdeformed structure has been observed with an intensity of 1.5±0.5%. The cascade of 9 coincidentγ rays has consecutive energy spacing of ∼160 keV. This corresponds to a dynamic moment of inertia which is almost constant at approx mately 25h 2 MeV−1. The band is interpreted as a signature=0, negative parity SD band with aπ51 V52 intrinsic intruder configuration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01292329
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  • 19
    Electronic Resource
    Electronic Resource
    Rotational bands in 167Hf (1999)
    Springer
    The European physical journal 6 (1999), S. 37-42 
    Details
    ISSN: 1434-601X
    Keywords: PACS: 23.20.Lv Gamma transitions and level energies – 27.70.+q 150 〈 A 〈 189
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: High-spin states in 167Hf, populated in the 141Pr(30Si, p3n)167Hf reaction, have been studied using the nordball Ge detector array. Three rotational cascades have been observed for the first time and the previously-known level scheme has been extended to significantly higher spin. Band-crossing effects are discussed within the framework of Woods-Saxon cranking calculations and are found to be in good agreement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500050314
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  • 20
    Electronic Resource
    Electronic Resource
    Insect behavior at the leaf surface and learning as aspects of host plant selection (1989)
    Springer
    Cellular and molecular life sciences 45 (1989), S. 215-222 
    Details
    ISSN: 1420-9071
    Keywords: Behavior ; learning ; leaf surface ; wax ; insects ; food selection ; secondary compounds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Direct observations on the feeding behavior of insect herbivores are uncommon, but important. The important aspects of host-plant selection by phytophagous insects that have been revealed by such observations are the role of chemicals in the leaf surface, and learning. There are few detailed reports of behavior at the leaf surface, but these indicate that many, if not all, insects exhibit behavior pattenrs that can be interpreted as an examination of the quality of the surface and acceptance or rejection may follow without further testing. A number of experiments show that chemicals from the leaf surface commonly contribute to the acceptability or otherwise of a plant and in most cases so far the active chemicals are of widespread occurrence, not having a specific association with the host plant. Some experiments show that the association between surface chemicals and plant palatability is learned, but in other cases there is evidence of an innate response. Habituation to deterrent chemicals has been demonstrated in the laboratory, but not in the field. Food aversion learning also occurs and may be important in dietary switching by polyphagous insects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01951806
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