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  • 11
    Electronic Resource
    Electronic Resource
    Effect of orotic acid on liver glycogen of different animal species (1976)
    Springer
    Cellular and molecular life sciences 32 (1976), S. 332-334 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effect of orotic acid on the liver glycogen content in the mice, frogs and catfish was studied. It was observed that the orotic acid significantly increases the glycogen content in the liver of mice and catfish as it does in rats. On the other hand it causes a fall of the glycogen level in frogs in experiments made both in autumn and spring. This effect was modified by amino acids administrated together with orotic acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01940822
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  • 12
    Electronic Resource
    Electronic Resource
    Wirkung verschiedener Temperaturen auf die Entwicklung und den Stoffwechsel von Ehrlich-Ascites-Karzinom (1962)
    Springer
    Naturwissenschaften 49 (1962), S. 400-401 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00632258
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  • 13
    Electronic Resource
    Electronic Resource
    Die Wirkung von Nukleinsäuren auf die Entwicklung des transplantierten Guérin-Tumors (1962)
    Springer
    Naturwissenschaften 49 (1962), S. 63-63 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00595393
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  • 14
    Electronic Resource
    Electronic Resource
    Experimental focal cerebral ischaemia in rabbits (1985)
    Springer
    Journal of neurology 232 (1985), S. 223-230 
    Details
    ISSN: 1432-1459
    Keywords: Experimental embolism ; Silver/gold ball ; Focal cerebral ischaemia ; Rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A highly reproducible form of experimental embolization of the intracranial arteries is presented in rabbits. The injection of a silver or gold ball into the internal carotid artery caused occlusion predominantly of the middle cerebral artery and/or its branches. At the moment when embolization took place, the characteristic signs of acute cerebral ischaemia occurred in the electroencephalogram, local cerebral blood flow and steady (DC) potentials. Several hours after the ball had been injected the extent of the focal lesions became recognizable on sections stained for myelin. The procedure is simple, rapid, inexpensive and practically always successful. The extent of the lesion may be influenced by the change of both the ball size and the posture of animals. Moreover, the site of occlusion is easily discernible both on radiographs and to the naked eye.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313784
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  • 15
    Electronic Resource
    Electronic Resource
    Cerebral ischaemia produced by homologous blood clot emboli in rabbit (1988)
    Springer
    Journal of neurology 235 (1988), S. 314-317 
    Details
    ISSN: 1432-1459
    Keywords: Autologous blood clot ; Embolization ; Rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 40 rabbits cerebral ischaemia was induced by autologous blood clot emboli injected into the middle cerebral artery. Autologous blood clot formed spontaneously (within 2 h) in a catheter fixed in the internal carotid artery. The effects of embolization were investigated on arterial blood pressure, respiration, local cerebral blood flow, locally available O2 (aO2), steady (DC) potentials and EEG. After embolization the blood pressure and the frequency of respiration decreased transiently. On the embolized side the local cerebral blood flow, aO2, the frequency and amplitude of the EEG diminished markedly and the DC potentials shifted to negative. Similar but less marked and short-lasting changes could be seen on the contralateral side. Pathological examination of the brains revealed extensive infarction with haemorrhagic components. The technique is a promising method for inducing stroke experimentally and offers various ways for its thorough investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314181
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  • 16
    Electronic Resource
    Electronic Resource
    Ion concentrations in serum and cerebrospinal fluid of patients with neuromuscular diseases (1982)
    Springer
    European archives of psychiatry and clinical neuroscience 231 (1982), S. 251-258 
    Details
    ISSN: 1433-8491
    Keywords: Ions ; Cerebrospinal fluid ; Neuromuscular diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 62 Patienten mit neuromuskulären Erkrankungen und bei 17 Kontrollpatienten wurde die Konzentration von Na+, K+, Ca2+, Mg2+, Cl− und anorganischem Phosphor (Pi) im Serum und im lumbalen Liquor vergleichend gemessen, und die Werte wurden statistisch bearbeitet. Obwohl keine für die verschiedenen Erkrankungstypen charakteristischen Veränderungen beobachtet werden konnten, ist die signifikante Erhöhung der Pi-Konzentration im Serum bei Duchenne-Dystrophie doch erwähnenswert. Die eventuellen Veränderungen der Ionenkonzentration im Serum und im Liquor können zur Diagnosestellung bei verschiedenen neuromuskulären Erkrankungen beitragen.
    Notes: Summary The Na+, K+, Ca2+, Mg2+, Cl−, and Pi concentrations in serum and lumbar CSF of 17 controls and 62 patients with neuromuscular diseases were determined and the values statistically evaluated. Although alterations in ion concentrations specifical to different groups were not observed in either of these biological fluids, the significant increase in serum Pi concentration in Duchenne muscular dystrophy seems to be remarkable. It is suggested that the possible alterations in the ion content of the serum and CSF may contribute additional data to the diagnosis of various neuromuscular diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00343295
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  • 17
    Electronic Resource
    Electronic Resource
    Correlation of individual symptoms and other clinical variables with cerebrospinal fluid amine metabolites and tryptophan in depression (1981)
    Springer
    European archives of psychiatry and clinical neuroscience 229 (1981), S. 345-353 
    Details
    ISSN: 1433-8491
    Keywords: CSF monoamines ; Depression ; Symptoms ; Tryptophan
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cerebrospinal fluid 5-hydroxyindoleacetic acid (5HIAA), homovanillic acid (HVA), and tryptophan in both CSF and plasma were measured in a carefully selected group of 33 depressed women. Strict and explicit inclusion and exclusion criteria were used, and CSF was taken under controlled circumstances. Seventeen operationally defined and uniformly rated psychiatric symptoms as well as global depression severity and 12 clinical background variables were correlated with the four biochemical parameters, using multivariate regression analysis based on Spearman's rank correlation coefficient according to the nature of the data. Global depression severity did not correlate with any of the biochemical variables; there were, however, significant correlations between CSF 5HIAA and anxiety, insomnia, and suicide on the one hand, and between CSF HVA and motor symptoms and paranoidity on the other hand. Background variables showed only a few-and much weaker-correlations. It was concluded that central monoamine metabolism does affect some particular psychiatric symptoms but is not parallel with the complex clinical construct of the depressive disease. Further studies using isolated psychopathological symptoms instead of nosological categories are suggested in clinical neurochemistry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01833162
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