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  • 1
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Analytical chemistry 24 (1952), S. 1576-1579 
    ISSN: 1520-6882
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    s.l. : American Chemical Society
    Analytical chemistry 26 (1954), S. 1914-1916 
    ISSN: 1520-6882
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    Child 31 (2005), S. 0 
    ISSN: 1365-2214
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Psychologie
    Notizen: Background  Bullying has been shown to be a serious problem amongst school children, but few studies have been population-based and included pre-school children.Methods  The study is part of a cross-sectional comparative study in 1984 and 1996, focusing on children's and their families’ health and welfare in the Nordic countries. At each point of time parents of 3000 randomly selected children aged 2–17 years in each of five Nordic countries received a postal questionnaire. Altogether approximately 20 000 questionnaires were completed. The prevalence of bullying, risk factors for bullying and possible effect factors were analysed.Results  Parents reported bullying of their child in 15.1% of the cases. Bullying varied from 7.2% in Sweden to about 20% in Denmark and Finland. There was a small increase in bullying from 13.7% in 1984 to 16.4% in 1996. Bullying was most frequent in boys (OR: 1.4) and in children 2–6 and 7–12 years old (OR: 2.0 and 2.2 compared with older children). Children of single parents and of parents with low education had increased risks (OR: 1.4 and 1.4). Children with chronic conditions had higher risks for being bullied (OR: 2.3). In 1996 children with psychiatric/nervous problems and hyperactivity had high risks for being bullied (OR: 8.8 and 10.5) and for bullying others (3.9 and 3.5). Being bullied was associated with poor thriving and psychosomatic and psychological problems. No countries had national interventions before 1984, but Sweden had early focused on the problem and implemented a strong national policy before 1996. After 1996 national anti-bullying policies were strengthened in the Nordic countries, most in Sweden and Norway.Conclusion  Bullying is common among Nordic children, including pre-school children. Bullying is a threat to children's health, and augments problems in children with chronic conditions. The low prevalence of bullying in Sweden may be a result from sustained, strong anti-bullying policies. There is still a need for continuing interventions.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 85 (2003), S. 0 
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: NCAM plays an essential role in neural development and regeneration. We have recently demonstrated a direct interaction between the fibronectin type III modules (F3) of NCAM and the extracellular part of the FGF receptor and also identified a binding site localized in the second F3 module. The corresponding peptide motif (FGL) activated the FGF receptor, promoted neuritogenesis and protected DA neurons in vitro. In a rat model of A-beta (amyloid-beta peptide) induced neurite toxicity, FGL rescued the deficit in learning and improved neuropathology. Thus, small artificial mimetics of NCAM with agonist-like effects are attractive lead-candidates for drug development for the treatment of neurodegenerative diseases.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd.
    Child 29 (2003), S. 0 
    ISSN: 1365-2214
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Psychologie
    Notizen: Background  In a recent project, commissioned by the European Union, a set of Child Health Indicators were identified and recommended for use in all Member States. In that work, by a group of European experts, children's development was one of the key areas that were reviewed to clarify its role in this set of indicators. This paper deals with neurological (in a broad sense), social and moral aspects of development; other aspects, such as nutrition and physical growth, mental health, quality of life were dealt with in other areas.Methods  A number of methods are used to monitor children's neurodevelopment, to identify early deviations that could be treated or alleviated. Few tests fulfil basic criteria of screening and quality of evidence. For Child Health Programmes, developmental surveillance is instead recommended. As a proxy to social development, as part of children's process of adaptation into society, education indicators are recommended, such as suggested by OECD and UNICEF. Moral development is discarded as an indicator, because norms and values vary too much between countries.Conclusion  For now the Child Health Indicators of Life and Development Project found no ground to recommend any particular method or combination of methods for a general monitoring of children's neurological, intellectual, language and moral development, and for including the results as national indicators of children's health and well-being in EU. For social development, indicators in the educational area seem most promising, as they have been proposed and used by OECD and UNESCO. In an ambitious monitoring programme, these indicators could be included as determinants of children's health and development.
    Materialart: Digitale Medien
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  • 6
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Science Ltd
    Child 29 (2003), S. 0 
    ISSN: 1365-2214
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Psychologie
    Notizen: ESSOP – the European Society for Social Paediatrics – was initiated in Lund, Sweden in 1977, and at the annual congress in Spetses, Greece, its 25th anniversary was celebrated. At the congress, Professor Lennart Köhler, who started the organization and for 10 years was its first Secretary General, presented his recollections from the life of ESSOP, its people, activities, strategies and ideologies, and the main lines of development over the years. This paper presents an edited version of his speech for the benefit of the readers of Child: Care, Health and Development.
    Materialart: Digitale Medien
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  • 7
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism 1042 (1990), S. 395-403 
    ISSN: 0005-2760
    Schlagwort(e): (Human U937 cell line) ; Arachidonic acid metabolism ; Cell differentiation ; Cyclooxygenase ; Icosanoid ; Phospholipase A"2
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Medizin , Physik
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    World journal of surgery 23 (1999), S. 816-824 
    ISSN: 1432-2323
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract. The use of endoscopic surgery has increased in gastrointestinal surgery since the introduction of laparoscopic cholecystectomy. It was the aim of this study to investigate the impact of endoscopic procedures in 1998. Laparoscopic cholecystectomy, fundoplication, repair of perforated peptic ulcer, gastric banding procedure, sigmoid resection for diverticulitis, and ileal pouch–anal anastomosis were investigated using techniques of technology assessment. Feasibility, efficacy, and effectiveness were used to evaluate the different types of operation. The statements were graded by three categories of evidence. Laparoscopic cholecystectomy and fundoplication have passed the test. Laparoscopic repair of perforated duodenal ulcer, gastric banding for morbid obesity, and sigmoid resection for diverticulitis are feasible and efficient but not effective today. Laparoscopy-assisted ileal pouch–anal anastomosis has been shown to be feasible but is not yet efficient and effective.
    Materialart: Digitale Medien
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    International journal of colorectal disease 13 (1998), S. 43-47 
    ISSN: 1432-1262
    Schlagwort(e): Key words Diverticular disease ; Laparoscopically assisted sigmoid resection ; Open sigmoid resection ; Recovery ; Morbidity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé Le but de cette étude est d'évaluer le devenir des patients ayant subi une sigmoïdectomie laparoscopique pour maladie diverticulaire. Vingt-neuf patients consécutifs ont été traités chirurgicalement pour une diverticulite colique. Vingt-sept des cas ont pu être opérés par laparoscopie, L'étude des dossiers cliniques d'un groupe-contrôle de 34 patients subissant une résection ouverte a servi de comparaison. Le taux de conversion est de 7,5%. Par laparoscopie, la durée de l'intervention chirurgicale a été plus longue (165 vs 121 minutes, P〈0,05), les pertes sanguines (182 vs 352 ml, P〈0,05) et les transfusions sanguines moindres (0 vs 16%). L'incidence des complications suivant la laparoscopie a été inférieure (2 fuites anastomotiques, 2 infections de plaie) en comparaison à la chirurgie conventionnelle. La convalescence du groupe laparoscopique a été plus rapide et la durée d'hospitalisation réduite (7,9 vs 14,3 jours, P〈0,05). Dans le groupe laparascopique, les douleurs au repos et aux mouvements ont été inférieures. Let coût du geste chirurgical laparoscopique a été inférieur en comparaison à la résection conventionelle (7185 vs 8975 DM). Dans cette série, la résection sigmoïdienne par laparoscopie pour maladie diverticulaire est sûre et plus rapide, la durée de guérison est plus rapide, la durée d'hospitalisation plus brève et les patients ont présenté moins de douleurs dans le groupe laparoscopique en comparaison avec la chirurgie conventionelle.
    Notizen: Abstract This study evaluated outcome in patients undergoing laparoscopically assisted sigmoid resection for diverticular disease. A total of 29 consecutive patients were treated surgically for colonic diverticulitis; in 27 of these laparoscopy was performed. The review of medical records from a control group of 34 patients undergoing open resection were used for comparison. The conversion rate was 7.5%. Using the laparoscopic technique the duration of surgery was longer (165 vs. 121 min, P〈0.05), blood loss less (182 vs. 352 ml, P〈0.05), and subsequent blood transfusion less (0 vs. 61%). The incidence of complications following laparoscopic resection was lower (two anastomotic leakages, two wound infections) than in the conventional group. Convalescence in the laparoscopic group was more rapid and hospital stay shorter (7.9 vs. 14.3 days, P〈0.05). In the laparoscopic group patients expressed less pain at rest and in motion. The cost of the laparoscopically assisted procedure was less than that of conventional resection (7185 vs. 8975 DM). In this series laparoscopically assisted sigmoid resection for diverticulitis proved safe. Recovery was faster, hospital stay was shorter, and patients expressed less pain than in conventional open surgery.
    Materialart: Digitale Medien
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Der Chirurg 68 (1997), S. 794-800 
    ISSN: 1433-0385
    Schlagwort(e): Key words: Colorectal surgery ; Laparoscopic techniques ; Cancer surgery ; Costs ; Technology assessment ; Schlüsselwörter: Colorectale Chirurgie ; laparoskopische Technik ; Carcinomchirurgie ; Kosten ; Technologiebewertung
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung. Ziel der Untersuchung war, die Wertigkeit der laparoskopischen colorectalen Chirurgie zu untersuchen. Von 131 Patienten wurden 80 (61 %) laparoskopisch operiert. Bei 13/93 (14 %) wurde konvertiert. 47 (59 %) litten an einem Carcinom, 41 wurden kurativ operiert. Zum Vergleich dienten 48 offen operierte Patienten. Die Komplikationsrate war nach laparoskopischer Technik reduziert, Reoperationen waren nicht notwendig, die Rekonvaleszenz war rascher; erste Nahrungsaufnahme und erster Stuhlgang traten früher auf. Die Krankenhausverweildauer war verkürzt (15,3 vs. 8,1 Tage). Die Schmerzen waren in Ruhe und Bewegung signifikant geringer. Resektatlänge, Resektionsabstände und Anzahl der entfernten Lymphknoten waren gleich. Portmetastasen wurden nicht beobachtet. Eine verminderte Morbidität, ein verkürzter Krankenhausaufenthalt, verminderte Schmerzen, eine schnellere Rekonvaleszenz bei adäquater Radikalität und akzeptablen Kosten sprechen für die laparoskopische Technik.
    Notizen: Summary. The aim of this study was to access the importance of the laparoscopic colorectal resection. Of 131 patients 80 were operated on laparoscopically. The conversion rate was 14 % (13/93). A total of 47 patients suffered from cancer. Curative resection was performed in 41 patients (87 %). For comparison, 48 patients who underwent open resection were used. The complication rate was lower after laparoscopy and no reoperation was performed. Patients recovered quicker and their first oral food intake and bowel movement were earlier. Hospital stay was shorter (15.3 vs. 8.1 days), and pain at rest and in motion was significantly reduced. Equal numbers of mesenteric lymph nodes were retrieved; adequate margins of resection could be obtained and the length of resected bowel did not differ. No port metastases were observed. Reduced morbidity, reduced hospital stay, reduced abdominal pain, quicker reconvalescence, and reduced overall health care costs are strong arguments in favor of laparoscopic colectomy.
    Materialart: Digitale Medien
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