ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Microbiological Transformations of Nonsteroidal Structures, VII. Microbiological Glucosidation of a Phenolic Hydroxyl Group5,7-Dichloro-2-methyl-8-quinolinol (1) is transformed to the 4-O-methyl-β-glucoside (2) by Sporotrichum sulfurescens (ATCC 7159). 5-Chloro-2-methyl-7,8-quinolinediol (3) yields the 7- and the 8-(4-O-methyl-β-glucoside) (4,5). 6-Hydroxytetralone forms also the 4-O-methyl-β-glucoside (7). Bis(4-acetoxyphenyl)methylenecyclohexane (8) is transformed after intermediary saponification to the mono-4O-methyl-β-glucoside (10) by Sporotrichum sulfurescens, whereas Rhizopus colinii (ATCC 8996) forms the unsubstituted mono-β-glucoside (11).
Notes:
5,7-Dichlor-2-methyl-8-chinolinol (1) wird mit Sporotrichum sulfurescens (ATCC 7159) in das 4-O-Methyl-β-glucosid 2 übergeführt. 5-Chlor-2-methyl-7,8-chinolindiol (3) ergibt sowohl das 7-als auch das 8-(4-O-Methyl-β-glucosid) (4,5). 6-Hydroxytetralon (6) bildet ebenfalls ein 4-O-Methyl-β-glucosid (7). Bis(4-acetoxyphenyl)methylencyclohexan (8) wird nach intermediärer enzymatischer Verseifung mit Sporotrichum sulfurescens in ein Mono-4-O-methyl-β-glucosid (10) umgewandelt, während Rhizopus colinii (ATCC 8996) ein unsubstituiertes β-Glucosid (11) bildet.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19761090632
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