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  • 1
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 99 (1978), S. 0 
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: In a family with perceptive, non-progressive hearing loss several of the members suffered from atopic dermatitis. The proband had a severe atopic dermatitis and an extremely high IgE value. Some of the family members suffered from atopic dermatitis, others from deafness, and some from both diseases. The co-existence of these two disorders has been previously described in two families. Atopic dermatitis and perceptive, non-progressive congenital deafness might be genetically associated.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 3 (1977), S. 0 
    ISSN: 1600-0536
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 382 (1979), S. 43-50 
    ISSN: 1432-2013
    Schlagwort(e): Slow fibres ; Contractile responses ; Effect of denervation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract 1. The contractile responses of single slow muscle fibres were investigated under isometric conditions. The fibres were isolated from normal and denervated iliofibularis muscles ofRana temporaria. Direct stimulation was achieved by external application of electrical pulses or depolarizing solutions (40 mM K and acetylcholine 10\t-6 g/ml). 2. Upon electrical stimulation normal slow fibres developed contractions whose amplitude increased steadily with the strength of the pulses. These contractions did not exceed 0.22 kg/cm2, and their rates of rise and fall were approximately 1/6 of those observed in twitch fibres. During pulses of several 100 ms duration the tension continued to rise slowly until the end of the pulses. Application of 40 mM K or acetylcholine resulted in contractures which reached maximum values of 1.71 and 1.87 kg/cm2, respectively, after less than 1 min; little relaxation occurred during the following minutes. 3. The responses of slow fibres denervated for 9−76 days differed in several respects from those of normal slow fibres. a) The contractions elicited by electrical stimulation became faster but their amplitude decreased; the relationship between tension and pulse strength remained, however, essentially unchanged. b) Small and short contractions could be observed during and at the end of stimulating current pulses. Their amplitude was independent of the amplitude and duration of the stimuli; they were blocked by tetrodotoxin and must be attributed to action potentials. c) The ability to develop and maintain tension was reduced. Maximum values of K- and acetylcholine contractures were generally only 50% of those observed in normal slow fibres. Maintenance of tension was markedly reduced in some fibres, less so in others. 4. It is concluded that incorporation of Na channels into its membrane does not transform the slow fibre into a type of fibre which resembles a twitch fibre.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Pflügers Archiv 372 (1977), S. 17-22 
    ISSN: 1432-2013
    Schlagwort(e): Slow muscle fibres ; Action potential ; Nerve stump ; Temperature
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A. Pyriformis and extensor longus digiti IV muscles of Rana temporaria were denervated by cutting the sciatic or peroneal nerve at various distances from the muscles. Slow fibres were identified by their membrane time constants, and examined for their ability to produce action potentials in response to intracellularly applied current pulses. B. The slow muscle fibres acquired the ability to generate action potentials several days after denervation. The duration of this latent period depended on the length of the peripheral nerve stump, and on the temperature at which the frogs were kept after the operation. C. At 18°C the latent period increased by 0.36 days per mm of sciatic nerve stump. At 11.5° C the corresponding value was 0.7 days/mm. The effect of length of the peroneal nerve was smaller than that of the sciatic nerve. D. It is suggested that the peripheral nerve stump serves as a reservoir of ‘trophic’ material which is transported towards the slow fibres at a rate of 2.8 mm/day (at 18° C) and seems to block the formation of Na channels. TheQ 10 value of this transport system would be 2.7.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Planta 129 (1976), S. 69-73 
    ISSN: 1432-2048
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The permeability of the plastid envelope during the development of Avena sativa plastids was investigated by light scattering and uptake of various labelled compounds (malate, succinate, glutamate, α-ketoglutarate, citrate, glycine, sucrose). The results presented show that a primary event during greening is a change in permeability, thereby allowing an increased transport of metabolites across the membranes of very early etio-chloroplast stages. The results are discussed in view of an adaption of the plastid envelope permeability to the changing requirements of externally synthesized precursors and intermediates during development.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Journal of cancer research and clinical oncology 94 (1979), S. 257-263 
    ISSN: 1432-1335
    Schlagwort(e): Yoshida ascites tumor ; Cyclophosphamide ; Alkylating agents ; Resistance and cross resistance
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A cyclophosphamide-resistant subline of a Yoshida ascites tumor was developed by giving increasing doses of the drug after transplantation. The effect of several alkylating agents on the cell proliferation of both the sensitive and resistant cell line was compared establishing dose response curves and D50 values. The developed subline revealed a 260 fold resistance to cyclophosphamide. It was completely cross-resistant to hydroperoxycyclophosphamide, whereas for triaziquone, N-oxide-mustard, and N-methyl-mustard only a partial cross resistance existed. These results give further evidence that cyclophosphamide and hydroperoxycyclophosphamide have the same mechanism of action. Regarding the other alkylating agents the results demonstrate differences concerning either the molecular mode of action or protecting effects. A decreased activation or uptake of substance is probably not the base for resistance.
    Materialart: Digitale Medien
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  • 7
    Digitale Medien
    Digitale Medien
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 8 (1975), S. 128-131 
    ISSN: 1600-5767
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Geologie und Paläontologie , Physik
    Notizen: Dynamical diffraction of thermal neutrons is treated for a plane single-crystal plate of magnetic neutron-absorbing material. It is shown that the results of the theory of dynamical X-ray diffraction can be used in the case of neutron diffraction, when the Fourier transforms of the polarizability are replaced by the Fourier transforms of the interaction potential divided by the kinetic energy of the neutrons. The Fourier transforms of the magnetic part of the interaction potential are calculated expicitly. In order to take the nuclear part of the interaction into account the method of the Fermi pseudopotential is used. The results are applied to the case of symmetrical Bragg reflection. There are two solutions for the intensity of the reflected beam as a function of the angle of neutron incidence, corresponding to the two possible directions of the neutron spin, parallel or antiparallel to the magnetic field in the crystal. It is shown that the positions of the maxima and the widths of the curves illustrating the intensity dependence on the angle of neutron incidence are different for the two possible spin directions and depend on the direction of the magnetization in the crystal. The total intensity of the reflected beam for the diffraction of unpolarized neutrons is obtained by averaging the intensities for the two possible spin directions.
    Materialart: Digitale Medien
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  • 8
    Digitale Medien
    Digitale Medien
    [s.l.] : Nature Publishing Group
    Nature 253 (1975), S. 122-123 
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] The experiments were performed on the right pyriformis muscle of Rana temporaria. This muscle is usually innervated by spinal branch IX; it has, however, been observed7 that occasionally the muscle receives additional motor axons from spinal branch VIII. One of these branches, usually IX, was cut ...
    Materialart: Digitale Medien
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  • 9
    facet.materialart.
    Unbekannt
    Roma : Periodicals Archive Online (PAO)
    Archivum historicum Societatis Iesu. 46 (1977) 225 
    ISSN: 0037-8887
    Thema: Theologie und Religionswissenschaft
    Notizen: OPERUM, QUAE IUDICANTUR, INDEX
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Archives of gynecology and obstetrics 228 (1979), S. 311-325 
    ISSN: 1432-0711
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
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