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  • 1
    Electronic Resource
    Electronic Resource
    Measurement of plasma catecholamines by high-performance liquid chromatography with electrochemical detection in intensive care patients after dobutamine infusion
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 567 (1991), S. 240-247 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80327-9
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Messung des Gasstoffwechsels der Cornea (1965)
    Springer
    Naturwissenschaften 52 (1965), S. 455-455 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00627064
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Untersuchungen zur Leistungsfähigkeit calciumselektiver Disk-Elektroden mit elektrisch geladenen und neutralen Liganden bei anaeroben Serummessungen (1978)
    Springer
    Research in experimental medicine 172 (1978), S. 75-81 
    Details
    ISSN: 1433-8580
    Keywords: Calciumselective disc-electrodes ; Electrochemical multimeasurementsystem ; Ionized serum-calcium ; Calciumselektive Disk-Elektroden ; Elektrochemisches Multimeßsystem ; Ionisiertes Serum-Calcium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Anaerob gewonnene Serumproben von gesunden Probanden wurden simultan mit drei zu einem System verbundenen ionenselektiven Scheiben-Elektroden im Durchfluß (elektrochemisches Multimeßsystem) auf ihren Ca++-Gehalt untersucht. Zwei der Sensoren enthielten elektrisch geladene Liganden, der dritte einen neutralen Carrier. Verwendung von neutralen Liganden in ionenselektiven Elektroden führt zu einer erheblichen Steigerung der Selektivität gegenüber H+- und NH 4 + -Ionen sowie einer deutlichen Verbesserung der Meßwertstabilität, Reproduzierbarkeit und Anzeigegeschwindigkeit.
    Notes: Summary Anaerobically prepared serum samples from healthy subjects were simultaneously analysed for Ca++ in a flow-through-system of three ion selective disc-electrodes (electrochemical multimeasurementsystem). Two of the sensors contained electrically charged ligands, the third contained a neutral carrier. With neutral carriers an improvement of performance was noted in that there was a large increase in selectivity toward H+-and NH 4 + -ions and a distinct enhancement of reproducibility.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851067
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Untersuchungen im strömenden Blut wacher Versuchstiere und des Menschen (1978)
    Springer
    Research in experimental medicine 172 (1978), S. 143-154 
    Details
    ISSN: 1433-8580
    Keywords: Haematocrit ; Blood electrolytes ; Conductometry ; Continuous measurements ; Hemodialysis ; Hämatokrit ; Blutelektrolyte ; Konduktometrie ; Fortlaufende Messungen ; Hämodialyse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der arterielle Hämatokrit und die Gesamtelektrolytkonzentration werden bei 3 Hämodialysepatienten fortlaufend mittels Konduktometrie gemessen. Anstieg des Hämatokritwertes während der Mahlzeiten, besonders wenn sie kohlenhydratreich sind, deuten auf Flüssigkeitsverluste aus dem Blut hin. Gleichzeitig weisen biphasische Veränderungen der Elektrolytkonzentration auf osmotische und diffusive Wasser- und Elektrolytverschiebungen hin. Blutvolumen- und Elektrolytkonzentrationsänderungen während und nach intravenösen Infusionen von Kolloid- und Krystalloidlösungen können ebenfalls verfolgt werden. Die sich aus den Messungen ergebenden quantitativen Aspekte werden diskutiert.
    Notes: Summary Arterial haematocrit and blood electrolyte concentrations are measured continuously by conductometry in three hemodialysis patients. Haematocrit elevation during meals, particularly when rich in carbohydrates, indicate fluid losses into the gut. Simultaneous biphasic responses in electrolyte concentration indicate osmotic and diffusional shifts of water and electrolytes. Similarly, blood volume and electrolyte concentration changes can be followed during and after intravenous infusions of colloid and crystalloid solutions. The quantitative aspects of such measurements are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851405
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  • 5
    Electronic Resource
    Electronic Resource
    Die Wirkung unkonjugierter Gallensäuren auf die Elektrolyt- und Wasserabsorption im proximalen Jejunum (1979)
    Springer
    Research in experimental medicine 175 (1979), S. 37-49 
    Details
    ISSN: 1433-8580
    Keywords: Unconjugated bile salts ; Electrolyte- and water-absorption ; Jejunum ; Conscious rat ; Unkonjugierte Gallensäuren ; Elektrolyt- und Wassertransport ; Jejunum ; wache Ratte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Einfluß von unkonjugiertem Cholat und Desoxycholat in physiologischer Dosierung auf den Netto-Volumen- und Elektrolyttransport wird mit Hilfe einer in-vivo-Perfusionstechnik am proximalen Jejunum der wachen Ratte untersucht und am selben Tier gegen Kontrollversuche verglichen. Unkonjugiertes Cholat und Desoxycholat in physiologischer Dosierung bewirken eine überwiegend reversible Netto-Resorptionsminderung bzw. Sekretionssteigerung für alle untersuchten Parameter. Insbesondere im Ausmaß ihrer Wirkung auf den Netto-Volumentransport lassen sich Unterschiede nach Dosis und Substrat erkennen. Die möglichen Wirkmechanismen unkonjugierter Gallensäuren auf den Elektrolyt- und Wassertransport werden diskutiert.
    Notes: Summary With an in vivo-perfusion-technique the influence of unconjugated bile salts (cholate, desoxycholate) on the net electrolyte and volume absorption is studied in the jejunum of conscious rats. The applied doses correspond to physiological concentrations in the intestine of rats. Control experiments were performed in the same animal. Cholate and desoxycholate diminish the net electrolyte and volume absorption resp. cause a net secretion. The effects are largely reversible. The extent of net volume absorption depends on the applied dose of each bile salt. The possible mode of action of unconjugated bile salts on the electrolyte and water absorption in the small intestine is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851232
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  • 6
    Electronic Resource
    Electronic Resource
    Die Wirkung von Desoxycholat auf die Elektrolyt- und Wasserabsorption im terminalen Ileum (1981)
    Springer
    Research in experimental medicine 178 (1981), S. 141-150 
    Details
    ISSN: 1433-8580
    Keywords: Desoxycholate ; Electrolyte and water absorption ; Ileum ; Conscious rat ; Desoxycholat ; Elektrolyt- und Wasserabsorption ; Ileum ; wache Ratte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit Hilfe einer in-vivo-Perfusionstechnik an der wachen Ratte wird die Wirkung von 10−3mol/l Desoxycholat (DC) am terminalen Ileum auf den Volumen- und Elektrolyttransport untersucht. Folgende Änderungen unter DC werden gegenüber den Kontrollen beobachtet: 1. Die Netto-Cl−-Absorption wird aufgehoben (P〈0,002). 2. Die Na+- und Volumenabsorption werden vermindert bzw. in eine Sekretion umgekehrt. 3. Die K+-Sekretion wird gesteigert (P〈0,01). DC führt zu einer Abnahme des Natrium-Wasser-Quotienten bedingt durch Änderungen der Permeabilität sowohl für Natrium wie auch für Wasser.
    Notes: Summary With an in vivo perfusion technique the influence of 10−3mol/l desoxycholate (DC) on the net electrolyte and volume absorption are studied in the terminal ileum of unanesthetized rats. Control experiments are performed in the same animal. The following data are observed: 1. There is a highly significant decrease in net Cl− absorption (P〈0.002). 2. The Na+ and volume absorption is diminished or reversed into secretion. 3. The K+ secretion is enhanced (P〈0.01). The sodium-water equivalent is reduced caused by alteration of the Na+ as well as the water permeability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851488
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  • 7
    Electronic Resource
    Electronic Resource
    Histamine release in the course of elective conventional cholecystectomy in aged patients: Problems in defining release in relation to specific intraoperative events (1992)
    Springer
    Inflammation research 36 (1992), S. C155 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effectiveness of an H1 −+H2-prophylaxis against perioperative acute pseudoallergic reactions in which histamine is involved, and against postoperative complications the incidence of which may be increased by these reactions, was the central problem of a randomized trial in 162 aged patients during elective conventional cholecystectomy. As main endpoint it was planned to use the systemic histamine release reaction, as it already had been defined for the conscious and anaesthetized human subject. However, it had to be reassessed and redefined for the intraoperative period after improvement of the plasma histamine assay and new findings about stress-induced histamine release and the kinetics of histamine release during certain phases of operation. Intraoperative release is, at present, defined solely as an increase of plasma histamine values after a particular action (phase of operation). It includes criteria concerning plasma histamine changes either in comparison to the base value before surgery or to the preceding value before the last surgical action. Histamine elevations must exceed the last value by more than 3 standard deviations of the analytical error (i.e. 200% if value 〈0.25 ng/ml and 40% above). Basic requirements for the histamine assay (quality control), correct sample taking and appropriate preparation have to be fulfilled over the whole trial period. When these criteria were applied to the 162 patients an overall incidence of histamine release during cholecystectomy of 55.6% was found with 9.7–20% during an individual phase of operation. The data of this study, performed under routine conditions, with a sufficient number of patients with elevated risk and event controlled plasma histamine values, lead to a better understanding of intraoperative histamine release, its incidence and extent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01997322
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Hemodynamic responses to noxious stimuli in brain-dead organ donors (1992)
    Springer
    Intensive care medicine 18 (1992), S. 493-495 
    Details
    ISSN: 1432-1238
    Keywords: Brain death ; Spinal reflexes and automatisms ; Organ donor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The case report presents evidence for the spinal origin of the marked hypertensive reponses to noxious stimuli that may occur in organ donors who fulfill the commonly accepted criteria of brain death. Cardiovascular spinal reflex activity does not invalidate these criteria. For the first time, the catecholamine plasma concentrations have been determined during spinal pressor reflex activity. Circulating epinephrine increased more markedly than norepinephrine in both cases, rising to 4.7 and 44 times the baseline concentration respectively. The relation between plasma norpinephrine and epinephrine suggests involvement of the adrenal medulla in the reflex arc. The literature on spinal hemodynamic reflexes is reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708589
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Transcutaneous $${\text{P}}_{{\text{O}}_{\text{2}} } $$ monitoring in anaesthesia (1976)
    Springer
    Intensive care medicine 2 (1976), S. 29-33 
    Details
    ISSN: 1432-1238
    Keywords: Transcutaneous $${\text{P}}_{{\text{O}}_{\text{2}} } $$ ; Monitoring of anaesthesia ; Induction phase ; End stage of anaesthesia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 23 patients 18 to 73 years old transcutaneous $${\text{P}}_{{\text{O}}_{\text{2}} } $$ , relative local perfusion and cardiorespirogram during induction and end stage of anaesthesia were monitored. This method allows continuous sufficiently exact estimation of $${\text{Pa}}_{{\text{O}}_{\text{2}} } $$ . The comparison between $${\text{tcP}}_{{\text{O}}_{\text{2}} } $$ and corresponding blood gas analysis from arterial samples showed a good correlation of r = 0.94. Thus continuous $${\text{tcP}}_{{\text{O}}_{\text{2}} } $$ registration enables quick diagnosis of hypoxia and its therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00571894
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  • 10
    Electronic Resource
    Electronic Resource
    Exteriorized lymphatico-venous shunts in conscious rats (1982)
    Springer
    Pflügers Archiv 393 (1982), S. 351-353 
    Details
    ISSN: 1432-2013
    Keywords: Hepatic lymphatic fistula ; intestinal lymphatic fistula ; thoracic duct fistula ; lymphatico-venous shunts ; conscious rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Surgical techniques for establishing fistulas of the hepatic and intestinal lymphatics and thoracic duct in conscious rats are described. Continuous recirculation of the lymph into the vena cava inferior is performed by a device which measures flow velocity before returning the lymph to the animal through a permanent venous catheter. Clotting is prevented in all cases by constant infusion of an anticoagulant solution (containing heparin or Na-citrate) into the top of the indwelling catheter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00581424
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    Paper (German National Licenses)
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