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  • 1
    Electronic Resource
    Electronic Resource
    FATIGUE, CREEP AND CREEP/FATIGUE BEHAVIOUR OF A NICKEL BASE SUPERALLOY AT 700°C (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 20 (1997), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— This paper presents the results of an experimental testing programme to examine the uniaxial creep, low cycle fatigue and creep/fatigue interaction behaviour of a Ni-base superalloy at 700°C. The material is used in the manufacture of aeroengine turbine discs. A creep continuum damage mechanics model is shown to be capable of accurately predicting the creep and creep rupture behaviour of the material. A healing term has been incorporated into the damage mechanics model to allow the behaviour under creep/fatigue conditions to be described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1997.tb01488.x
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  • 2
    Electronic Resource
    Electronic Resource
    House dust mite allergen levels in two cities in Canada: effects of season, humidity, city and home characteristics (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 25 (1995), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The homes of 120 patients with asthma, 57 in Vancouver and 63 in Winnipeg, were studied. The characteristics of the homes were assessed by a questionnaire. Dust samples were collected and the indoor relative humidity was measured four times during the year covering all four seasons in both cities. Mite allergen levels were determined using monoclonal antibodies against Der p I and Der f I by the ELISA method. The mean levels of both mite allergens in mattress and floor samples in the homes in Vancouver and in Winnipeg were relatively low for all seasons. Mite allergen levels were found to be associated with city, season and individual home differences. They were significantly higher in Vancouver than in Winnipeg. Der p I and Der f I in mattress samples in both cities and Der f I in floor samples in Vancouver, varied by season. The indoor relative humidity level in the homes in Vancouver were also significantly higher than those in Winnipeg. There was, however, no significant association between the levels of indoor relative humidity and the levels of mite allergens after adjusting for variations in city, season and individual home. Although individual home differences were highly associated with mite allergen levels, only a few home characteristics were found to be related to mite allergen levels such as the type and the age of the home, the type of heating, the use of feather pillows and the number of occupants in the homes. Whether low levels of mite allergens are partially responsible for the relatively low prevalence of childhood asthma in Canada remains to be investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1995.tb01035.x
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  • 3
    Electronic Resource
    Electronic Resource
    Designing a Monitoring Network for Contaminated Ground Water in Fractured Chalk (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 37 (1999), S. 0 
    Details
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: One of the challenges of monitoring network design in a fractured rock setting is the heterogeneity of the rocks. This paper summarizes the activities and problems associated with the monitoring of contaminated groundwater in porous, low-permeability fractured chalk in the Negev Desert, Israel. Preferential flow documented in the study area required siting the monitoring boreholes in the predominant fracture systems. Lineaments traced from aerial photographs were examined in the field to sort out the large-extension, through-going, multilayer fracture systems crossing the study area. At each proposed drilling site, these fractures were exposed below the sediment cover using trenches. Slanted boreholes were drilled at a distance from the fracture systems so that each borehole would intersect the targeted fracture plane below the water table. Based on their short recovery period and contaminated ground water, these newly drilled, fracture-oriented boreholes appeared to be better connected to preferential flowpaths crossing the industrial site than the old boreholes existing on site. Other considerations concerning the drilling and logging of monitoring boreholes in a fractured media were: (1) coring provides better documentation of the vertical fracture distribution, but dry augering is less costly and enables immediate ground water sampling and the sampling of vadose rock for contaminant analysis; (2) caliper and TV camera logs appear to provide only partial information regarding the vertical fracture distribution; and (3) the information gained by deepening the monitoring boreholes and testing fractures crossing their uncased walls has to be carefully weighed against the risk of potential cross-contamination through the monitoring boreholes, which is enhanced in fractured media.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6584.1999.tb00956.x
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  • 4
    Electronic Resource
    Electronic Resource
    Iodide or l-Thyroxine to Prevent Recurrent Goiter in an Iodine-Deficient Area: Prospective Sonographic Study (1997)
    Springer
    World journal of surgery 21 (1997), S. 10-14 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In a randomized study, prevention of goiter recurrence with l-thyroxine was compared with pure iodide substitution after thyroid surgery for nodular goiter in an iodine-deficient area. Altogether 107 patients were followed up for 52 weeks after thyroid resection. The thyroid volume was determined sonographically. Free thyroxine, total thyroxine, thyrotropin, thyroglobulin, and antibodies to thyroglobulin and thyroid peroxidase were measured. The thyroid volume decreased slightly over the course of a year in the two therapy groups. There was no significant difference between the two groups. Recurrences were seen with both l-thyroxine medication and iodide substitution. The thyroglobulin levels fell significantly over the 52-week follow-up period in the iodide group. Antibody formation was not observed under iodine substitution. In an area of iodine deficiency, substitution with iodide is just as effective as medicating the patients with l-thyroxine for preventing recurrences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002689900186
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  • 5
    Electronic Resource
    Electronic Resource
    Adult medulloblastoma: review of 13 cases with emphasis on MRI (1995)
    Springer
    Neuroradiology 37 (1995), S. 104-108 
    Details
    ISSN: 1432-1920
    Keywords: Brain neoplasm diagnosis ; Magnetic resonance imaging ; Medulloblastoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Medulloblastomas are generally associated with childhood, but 14–30% occur in adults, accounting for 1% of adult central nervous system tumors. While approximately one third of adult medulloblastomas present as vermian tumors similar to those seen in childhood, the majority differ substantially from the childhood variety. In this series of 13 patients, 5 had lateral, seemingly extra-axial masses in the cerebellopontine angle or at the tentorium, simulating meningiomas or acoustic neuromas, but angiographic hypovascularity in 2 of the latter suggested a diagnosis other than meningioma. Of 4 paramedian tumors, 3 diffusely infiltrated the cerebellar white matter, showed little or no gadolinium enhancement and were not associated with hydrocephalus. Hydrocephalus was present in less than half of our patients; in childhood the reported incidence is 85–100%. A possible association with pregancy was noted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588622
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  • 6
    Electronic Resource
    Electronic Resource
    Adult medulloblastoma: review of 13 cases with emphasis on MRI (1995)
    Springer
    Neuroradiology 37 (1995), S. 104-108 
    Details
    ISSN: 1432-1920
    Keywords: Key words Brain neoplasm ; diagnosis ; Magnetic resonance imaging ; Medulloblastoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Medulloblastomas are generally associated with childhood, but 14–30 % occur in adults, accounting for 1 % of adult central nervous system tumors. While approximately one third of adult medulloblastomas present as vermian tumors similar to those seen in childhood, the majority differ substantially from the childhood variety. In this series of 13 patients, 5 had lateral, seemingly extra-axial masses in the cerebellopontine angle or at the tentorium, simulating meningiomas or acoustic neuromas, but angiographic hypovascularity in 2 of the latter suggested a diagnosis other than meningioma. Of 4 paramedian tumors, 3 diffusely infiltrated the cerebellar white matter, showed little or no gadolinium enhancement and were not associated with hydrocephalus. Hydrocephalus was present in less than half of our patients; in childhood the reported incidence is 85–100 %. A possible association with pregnancy was noted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588622
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  • 7
    Electronic Resource
    Electronic Resource
    Acute Inferior Cardiac Inflow Obstruction Resulting from Inadvertent Surgical Closure of a Prominent Eustachian Valve Mistaken for an Atrial Septal Defect (1999)
    Springer
    Pediatric cardiology 20 (1999), S. 155-157 
    Details
    ISSN: 1432-1971
    Keywords: Key words: Eustachian valve — Iatrogenic closure — Lower cardiac inflow obstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A 5-month-old boy with a VACTERL syndrome underwent cardiac surgery for correction of a common arterial trunk and closure of an atrial septal defect. A prominent Eustachian valve was mistaken for the atrial septum and surgically closed. Thirty months later, after gradual shrinking of the foramen ovale with associated reduction of the right-to-left shunt, the boy presented with acute symptoms of a lower inflow obstruction, characterized by hepatomegaly and engorged abdominal vein pattern (Medusa's head). The boy was reoperated successfully after the condition had been recognized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002469900427
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  • 8
    Electronic Resource
    Electronic Resource
    Host defense within the urinary tract. I. Bacterial adhesion initiates an uroepithelial defense mechanism (1996)
    Springer
    Pediatric nephrology 10 (1996), S. 568-572 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Urinary tract infection ; Bacterial adhesion ; Uroepithelial defense mechanism ; Ligand-receptor interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Uroepithelial defense has been suggested to contribute to the local host resistance against ascending urinary tract infection. The cellular mechanism, however, is not known. In this study, bacterial growth was measured under the direct and indirect influence of uroepithelial cells. To study if a specific ligand-receptor interaction is required for uroepithelial cell (UEC) activation, isogenic Escherichia coli mutants expressing either mannose-sensitive, mannose-resistant (p), or mannose resistant (s) pili were tested for their capacity to induce the UEC defense mechanism. The antibacterial effect of UEC was abolished either by performing coculture in chambers with a fluid-permeable membrane which separates UEC from bacteria or by inhibiting membrane contact using the antiadherence factor pentosane polysulfate. No difference between the various types of pili could be shown. All E. coli strains adhered comparably to the UEC and were subsequently suppressed in their growth. Even a “naked” mutant without expression of common pili showed a similar behavior. In conclusion, bacterial growth suppression depends on direct contact between the UEC and bacteria, but is independent of common pili expressed on E. coli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050162
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  • 9
    Electronic Resource
    Electronic Resource
    Discovery of a planet orbiting a binary star system from gravitational microlensing (1999)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 402 (1999), S. 57-59 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The properties of the recently discovered extrasolar planets were not anticipated by theoretical work on the formation of planetary systems, most models for which were developed to explain our Solar System. Indeed, the observational technique used to detect these planets (measurement of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/46990
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  • 10
    Electronic Resource
    Electronic Resource
    The regulation of trehalose metabolism in insects (1996)
    Springer
    Cellular and molecular life sciences 52 (1996), S. 433-439 
    Details
    ISSN: 1420-9071
    Keywords: Trehalose ; insect haemolymph ; neuropeptides ; insect fat body ; fructose 2,6-bisphosphate ; insect flight muscle ; regulation of trehalase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Trehalose is a non-reducing disaccharide comprising two glucose molecules. It is present in high concentration as the main haemolymph (blood) sugar in insects. The synthesis of trehalose in the fat body (an organ analogous in function to a combination of liver and adipose tissue in vertebrates) is stimulated by neuropeptides (hypertrehalosaemic hormones), released from the corpora cardiaca, a neurohaemal organ associated with the brain. The peptides cause a decrease in the content of fructose 2,6-bisphosphate in fat body cells. Fructose 2,6-bisphosphate, acting synergistically with AMP, is a potent activator of the glycolytic enzyme 6-phosphofructokinase-1 and a strong inhibitor of the gluconeogenic enzyme fructose 1,6-bisphosphatase. This indicates that fructose 2,6-bisphosphate is a key metabolic signal in the regulation of trehalose synthesis in insects. Trehalose is hydrolysed by trehalase (E.C. 3.2.1.28). The activity of this enzyme is regulated in flight muscle, but the mechanism by which this is achieved is unknown. Trehalase from locust, flight muscle is a glycoprotein bound to membranes of the microsomal fraction. The enzyme can be activated by detergents in vitro and by short flight intervals in vivo, which indicates that changes in the membrane environment modulate trehalase activity under physiological conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01919312
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