Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Cardiovascular drug reviews 1 (1983), S. 0 
    ISSN: 1527-3466
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Experimental Cell Research 60 (1970), S. 454-456 
    ISSN: 0014-4827
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 36 (1958), S. 651-655 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Experimentelle Gerinnungs-und Abscheidungsthromben (gemischte Thromben) zeigen im Tierversuch unter der Behandlung mit Thrombocid in relativ kleinen Dosen (2 mg/kg) eine Einschmelzung der Fibrinstrukturen, die mit charakteristischen morphologischen Veränderungen einhergeht. Das medikamentös aktivierte fibrinolytische Potential des Blutes führt zu einem — im wesentlichen retrograd verlaufenden — Abbau bis zur vollständigen Rückbildung von Gerinnungsthromben bzw. Gerinnungsanteilen von Abscheidungsthromben. Da die aus Plättchenkonglutinaten bestehenden Haftstellen von Abscheidungsthromben nicht angegriffen werden, ist die Gefahr einer Mobilisierung von Thromben gering einzuschätzen.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 267 (1970), S. 20-30 
    ISSN: 1432-1912
    Keywords: Embryotoxic Actions ; Trypan Blue ; Time Factor ; Trypanblau ; Embryotoxicität ; Behandlungszeitpunkt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The embryotoxic effect of a single dose of trypan blue given to pregnant mice (NMRI/Han-strain) on different days of pregnancy was studied. Seven groups each comprising 10–27 animals were subcutaneously injected with 1% trypan blue solution in a dose of 100 mg/kg body weight. The injection was performed on the 6th, 7th, 8th, 9th, 10th, 11th or 14th day of gestation. 40 animals, forming a control group received a single injection of saline over the same period. The findings were as follows: 1. A statistically higher rate of malformations in comparison to the control group is found to occur when the injection of trypan blue is made between the 6th and 10th day of pregnancy. Within this period the strongest teratogenic activity is observed when the trypan blue is administered on the 8th day of gestation. 2. The rate of resorptions in trypan blue treated animals over the period of pregnancy examined shows a significant increase over that of the control group. Here again the maximum is reached when the trypan blue has been injected on the 8th day. The effect of earlier and later injections is noticeably less. 3. The rate of retardation is increased by injections of trypan blue from the 8th day of gestation onward and by the 14th day the maximum has still not been attained. The morphology of the observed resorptions as well as that of the retarded and malformed fetuses is described.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 267 (1970), S. 31-40 
    ISSN: 1432-1912
    Keywords: Embryotoxic Actions ; Trypan Blue ; Dose Response ; Trypanblau ; Embryotoxicität ; Dosis-Wirkungs-Beziehungen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The embryotoxic effect of trypan blue on pregnant mice of the NMRI-strain was studied in relation to the dose injected. In addition, the acute toxicity of trypan blue in the adult mouse was determined and compared with the fetal toxicity. The findings were as follows: 1. The acute toxicity of trypan blue given in 1% solution, was determined. The LD50 adult=267 mg/kg when the injection is made subcutaneously. 2. In all treated animals, whatever the size of the injected dose-25 mg/kg, 50 mg/kg, 100 mg/kg or 200 mg/kg-a significant increase is observed both in the overall embryotoxic activity and in the resorption-, malformation- and retardationrates, compared to non-treated animals. Malformation- and retardation-rates as well as the overall embryotoxic activity are found to increase in parallel with increasing dose without a maximum having been attained at 200 mg/kg. In contrast, the rate of resorptions appears to be independent of the dose. 3. The dose that allows 50% of all implantations to evolve into fetuses, showing no recognizable damage-is in the region of 67 mg/kg. This amounts to approximately 1/4 of the LD50 adult
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 270 (1971), S. 316-318 
    ISSN: 1432-1912
    Keywords: Carmine ; Embryotoxic Effects ; Time of Administration ; Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 235 (1983), S. 153-155 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 340 (1966), S. 352-359 
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The physical-optical properties of hemosiderin or siderin were investigated microspectrophotometrically. Based on the absorption spectrum of erythrocytes and of Fe(OH)3 solutions, the absorption maxima occuring in experimentally induced siderin and hemosiderin (by injecting the iron solution and by implantation of blood) could be defined, as well as in human siderin: 1. The absorption at 280 mμ is due to the organic protein carrier-substance containing tyrosin and tryptophane. 2. The iron component in the siderin causes an absorption at 330–360 mμ. The position of the maximum of the absorption depends on different factors. 3. The soret band (around 410 mμ) could not be demonstrated constantly: with increasing age of the experimentally induced siderin and hemosiderin, the absorption disappears at 410 mμ. 4. Human siderin shows in the same properties of absorption, yet the component haem may be missing.
    Notes: Zusammenfassung In mikrospektrophotometrischen Untersuchungen wurden die physikalischoptischen Eigenschaften des Hämosiderins bzw. Siderins untersucht. Ausgehend vom Absorptionsspektrum von Erythrocyten und Lösungen von Fe(OH)3 konnten die auftretenden Absorptionsspektren im experimentell erzeugten Siderin (Injektion von Eisenlösung) und Hämosiderin (Blutimplantation) sowie menschlichem Siderin geklärt werden: 1. Die Absorption bei 280 mμ ist auf die proteinhaltige organische Trägersubstanz mit tyrosin- und tryptophanhaltigen Eiweißkörpern zurückzuführen. 2. Die Eisenkomponente im Siderin bedingt eine Absorption bei 330–360 mμ, wobei die Lage des Absorptionsmaximums von verschiedenen Faktoren abhängig ist. 3. Die Soretbande (um 410 mμ) war nicht konstant nachweisbar. Mit zunehmendem Alter von experimentell erzeugtem Siderin und Hämosiderin verschwindet die Absorption bei 410 mμ. 4. Menschliches Siderin weist gleiche Absorptionseigenschaften auf, wobei die Hämkomponente fehlen kann.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 128 (1969), S. 28-39 
    ISSN: 1432-0568
    Keywords: Arterial supply ; Corpus callosum ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An 27 Katzen beiderlei Geschlechts wurde die Blutversorgung des Corpus callosum untersucht. Dabei wurden folgende Befunde erhoben: Der Balken der Katze wird im Bereich des Rostrum und Genu sowie im vorderen und mittleren Truncuabschnitt aus der Arteria cerebri anterior versorgt und zwar über Äste, die den Arteriae pericallosae und den Arteriae genu corporis callosi entstammen. Diese Äste wurden als Arteriae callosi superiores und inferiores bezeichnet. Lediglich im hinteren Truncusabschnitt und im Splenium erfolgt die Versorgung neben Ästen der A. pericall. auch über solche der Arteriae cerebri mediae und posteriores. Die Blutgefäße treten dolchartig in den Balken ein, teilen sich dann baumartig weiter auf und gehen in ein Capillarnetz über, das in Richtung des Nervenfaserverlaufes ausgezogen ist. Auf in der Literatur bereits bekannte, aber oft vernachlässigte Besonderheiten der Arteria carotis interna und des Circulus arteriosus wird hingewiesen.
    Notes: Summary In investigations on 27 cats of both sexes, the arterial supply of the corpus callosum was studied. The findings are as follows: In the region comprising rostrum and genu as well as in the fore and middle trunk sections, blood supplied by branches of the arteriae pericallosae and the arteriae genu corporis callosi which originate from the arteria cerebri anterior. These branches were designated arteriae callosi superiores and inferiores. However, in the posterior section of the trunk and in the splenium the blood is supplied by branches of the aa. pericall. and, in addition, by branches of the arteriae cerebri media and posteriores. The blood vessels penetrate the corpus callosum in bayonet fashion, then arborise and finally become a capillary network which is elongated in the direction of the course of the nerve fibres. Attention is drawn to peculiarities of the arteria carotis interna and the circle of Willis which, although known in the literature, are rarely referred to.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 141 (1973), S. 251-264 
    ISSN: 1432-0568
    Keywords: Closure of neural tube ; Cell necrosis ; Normal mouse embryos ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Spontaneous cell death in the developing brain of 8.5–9 day old mouse embryos has been investigated with the electron microscope. Before closure of the neural tube, areas of cell death are found at the neuro-somatic junction. After closure of the neural tube degenerating cells are found in the dorsal midline of the prospective diencephalon. Ultrastructurally, cell degeneration is marked by chromatin condensation, increase in electron density of the structures in the cytoplasm and, in later stages, by a marked pycnosis of the dying cell. After fragmentation, the necrotic material as well as entire pycnotic cells are phagocytized and digested by cells of the neuroepithelium. An invasion of macrophages has not been observed. The significance of cell necrosis is discussed in relation to the normal formation of the neural tube and to the occurrence of certain induced malformations (exencephalies).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...