ISSN:
0935-6304
Keywords:
Thin layer chromatography, TLC
;
Ion exchange resin plates/tert-butyl alcohol, H2O, Na2HPO4, Nacl; ethanol, H2O, Na-acetate, NaCl
;
Sulfonamides and other chemotherapeutic substances
;
Qualitative analysis
;
Effect of pH variation on Rf values
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A thin-layer chromatographic method is described for sulfonamides and some other chemotherapeutic compounds. Ion-exchange resin precoated plates (Fixion 50 × 8 Na+, Chinoin, Budapest or Polygram Ionex-25 SA-Na, Macherey-Nagel and Co.,Düren, FRG) are employed with Na2HPO4 or Na-acetate (adjusted to different pH values) containing NaCl and tert-butyl alcohol or ethanol as developing solvent system. For qualitative and/or semiquantitave determinations the chromatograms can be stained: (A) with o-tolidine, after chlorination; (B) with p-dimethylaminobenzaldehyde; (C) with p-dimethylaminocinnamaldehyde.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240040608
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