ISSN:
1572-9931
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The mouse genes for the serine proteases trypsin (Try-1,chymotrypsin B (Ctrb),and elastase (Ela-1)were chromosomally assigned using Southern blot hybridization of mouse × Chinese hamster cell hybrid DNA. cDNA probes for the three genes were hybridized to cell hybrid DNA cleaved with BamHI or HindIII and the segregation of Try-1, Ctrb,and Ela-1was correlated with the segregation of mouse chromosomes. Try-1is located on chromosome 6, Ctrbis on chromosome 8, and Ela-1is on chromosome 15. The three genes fall into three syntenic groups that are conserved in the mouse and human genomes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01535633