ISSN:
1432-1203
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Linkage analysis has been carried out in 11 kindreds with autosomal recessive polycystic kidney disease (ARPKD) using the genetic marker 3'HVR, closely linked ( $$\hat \theta = 0.05$$ ) to the gene of the autosomal dominant type. Close linkage ( $$\hat \theta \leqq 0.20$$ ) between the locus of the marker and that of ARPKD can be excluded. These data strongly suggest that the loci for the autosomal recessive and dominant forms of polycystic kidney disease are not allelic.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00284473