Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 40 (1991), S. S77 
    ISSN: 1432-1041
    Keywords: Atherosclerosis ; lipid peroxidation ; antioxidants ; probucol ; WHHL rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Probucol has been used as a lipid-lowering agent for over 10 years. Lately it has been found that its antiatherogenic action is due mainly to its antioxidative capacity, in addition to its known lipid-lowering effect. To study the antioxidative capability of probucol and its influence on plaque developement we used the animal model of the LDL-receptor-defective Watanabe heritable hyperlipidemic (WHHL) rabbit. In this study we measured all lipid values before and after probucol feeding and compared them with corresponding values in untreated controls. Probucol levels were determined, as were the physiological antioxidants alpha and gamma tocopherol (vitamin E). Thiobarbituric reactive substances were measured in plasma as a parameter for lipid peroxidation. In addition to the biochemical measurements the plaque area was analyzed macroscopically and microscopically to check the antiatherosclerotic effect and correlate it with the biochemical parameters. In four experiments we showed that probucol treatment in WHHL rabbits decreases the progression of atherosclerotic plaques by way of a combined lipid-lowering and antioxidative effect.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1435-2451
    Keywords: Computed tomography ; Pelvis ; Computertomographie ; Becken
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Computertomographie liefert als einzige Untersuchungsmethode in der Radiologie horizontale Schnitte. Auch Weichteile, Tumoren, Bänder und Hämatome können beurteilt werden. Anderweitig schwierig zu untersuchende Bezirke wie Acetabulum, Kreuzbein und Iliosacralfuge kommen gut zur Darstellung. Die Untersuchung ist für den Patienten nicht belastend. Die Ausstellung zeigt Beispiele für Frakturen am Becken, die z.T. nur durch die CT erkannt wurden. Ebenso werden Beispiele für Tumoren, Hüftkopfnekrosen und Beckenosteomyelitis demonstriert.
    Notes: Summary Computed tomography is the only method of radiological examination to show horizontal sections of the patient. Soft tissues, tumors, ligaments and hematomas can be evaluated. Regions, such as the acetabulum, os sacrum and iliosacral joint, that are difficult to examine by other means can be displayed. The examination is of little harm to the patient. The exhibition shows examples of fractures of the pelvis, part of which could only be recognized by CT. There are also examples of tumors, femoral-head necrosis and osteomyelitis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...