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  • 1
    Electronic Resource
    Electronic Resource
    Modification of metal/GaN contacts with GaAs interlayers (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 6539-6541 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have investigated feasibility of GaAs interlayers for the metal/GaN interface with synchrotron-radiation photoelectron spectroscopy. We have found that the use of piranha/HCl solutions is effective as a surface cleaning technique for GaN. We have confirmed that (111) GaAs grows epitaxially on a (0001) GaN substrate. Pd/GaAs/GaN sandwich structures have been successfully fabricated with molecular beam epitaxy. We have confirmed the GaAs interlayer modifies the band diagram at the metal/GaN interface. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.370158
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  • 2
    Electronic Resource
    Electronic Resource
    Characterization of carrier-trapping phenomena in ultrathin chemical oxides using x-ray photoelectron spectroscopy time-dependent measurements (1999)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 74 (1999), S. 2011-2013 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report a technique to characterize carrier-trapping phenomena in SiO2 by measuring the Si 2p core-level energy of Si substrates covered with thin SiO2 layers as a function of x-ray irradiation time. It is found that the Si 2p peak energy, which corresponds to the band bending at the SiO2/Si interface, changes as the x-ray irradiation time increases. We attribute this to carrier-trapping phenomena in SiO2. By using this technique, it is found that the carrier-trapping phenomena differ remarkably among several chemical oxides. We also discuss the atomic structure of the traps that cause the trapping phenomena. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.123730
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  • 3
    Electronic Resource
    Electronic Resource
    Synthetic surfactants for protecting cultured fish against toxic phytoplankton (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Aquaculture research 29 (1998), S. 0 
    Details
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Polyoxyethylene alkyl esters, which are surface-active agents, were chemically synthesized from fatty acids (C12-C18) on reaction with different moles of polyethylene oxides, and were tested for effectiveness against the toxic raphidophytes Chattonella marina (Subrahmanyan) Hara & Chihara and C. antiqua (Hada) Ono. The synthetic surfactants destroyed cultured cells from these two species. Although the synthetic surfactants also exhibited ichthyotoxicity, this was lowered by increasing the molarity of ethylene oxide (EO) in alkyl ester molecules. Young yellowtail, Seriola quinqueradiata Temminck & Schlegel, survived exposure to C. marina (5000-5500 cells mLT−1) or C. antiqua (3000-3500 cells mL−1) cultures with the addition of 4-5 p.p.m. oleyl ester EO 14, but died within an hour without the addition of this surfactant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2109.1998.00239.x
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  • 4
    Electronic Resource
    Electronic Resource
    Molecular cloning of a class IV chitinase allergen from Japanese cedar (Cryptomeria japonica) pollen and competitive inhibition of its immunoglobulin E-binding capacity by latex C-serum (2005)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 35 (2005), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Japanese cedar (Cryptomeria japonica) pollinosis is one of the most prevalent allergic diseases in Japan. Only three C. japonica allergens, Cry j 1, Cry j 2, and CJP-6, have been characterized. The full IgE-binding spectrum of C. japonica pollen allergens demonstrates that many allergens remain to be identified.Objective The aim of this study was to characterize a novel allergen with a high frequency of IgE binding.Methods The cDNA coding for a high-frequency IgE-binding protein, designated CJP-4, was cloned from the total mRNA of C. japonica pollen. The corresponding native allergen was purified by affinity precipitation with colloidal chitin and gel chromatography. The IgE-binding ability of purified native CJP-4 was characterized by ELISA and ELISA inhibition.Results The CJP-4 cDNA encoded 281 amino acids with significant sequence homology to class IV chitinases. Purified native CJP-4, migrated as a homogeneous 34-kDa protein on SDS-PAGE, revealed endochitinase activity on native PAGE. The purified protein displayed the ability to bind IgE from all patients tested (31/31) in ELISA, whereas Cry j 1 bound to IgE at a 71% frequency (22/31). Pre-incubation with latex C-serum completely inhibited the reaction of pooled sera IgE from patients with C. japonica pollinosis and/or latex allergy to purified CJP-4.Conclusion We identified CJP-4 as a novel and fourth C. japonica chitinase allergen with high IgE-binding frequency. The competitive IgE-binding profile between C. japonica chitinase and latex C-serum indicated that C. japonica chitinase should be an important pan-allergen in C. japonica pollen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.2005.02167.x
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  • 5
    Electronic Resource
    Electronic Resource
    Identification of T-cell epitope sequences on an important mite antigen (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 27 (1997), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background T-cell epitopes on Der 1 and Der 2 groups, the major mite allergens, have been intensively analysed, while those on the other important allergens remain to be elucidated. We have cloned four cDNAs coding for important mite allergens on the basis of frequency and capacity of IgE binding. Stimulatory action of glutathione S-transferase-fused Mag1 on lymphocytes from mite-allergic patients was relatively high among them.Objective To identify T-cell epitopes on Mag1, we studied the stimulating activity of truncated Mag1 proteins and synthetic peptides on proliferative response of lymphocytes from mite antigen-immunized mice and mite-sensitive patients.Methods Truncated Mag1 proteins were expressed as a fusion protein with β-galactosidase in Escherichia coli pop2136 carrying a variety of deleted Mag1 inserts. Murine T-cell epitope regions were estimated by the truncated antigen-induced lymphocyte proliferation assay. Overlapping peptides covering the whole sequence of the presumed T-cell epitope regions were synthesized to identify the epitope core. sequences using murine and human Mag1-specific T-cell lines.Results Amino acid range 56–70 on Mag1 molecule showed remarkable stimulatory action on murine T cells, while amino acid ranges 51–65 and 86–100 had potent stimulatory activity on human T cells.Conclusion These results suggest that Mag1 is a valuable antigen suitable for studies on T-cell responses and T-cell epitopes in mice and humans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1997.tb01261.x
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  • 6
    Electronic Resource
    Electronic Resource
    Response of human gingival fibroblasts to prostaglandins (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 30 (1995), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effects of various prostaglandins (PGs) on the functions of human gingival fibroblasts (Gin-1 cells; ATCC CRL 1292) were examined by phase-contrast microscopy, cell-counting and radioautographic experiments. Tested PGs were PGA1, PGA2, PGB1, PGB2, PGD2, PGE1, PGE2, PGF1α, PGF2α, PGI2, 6-keto-PGF1α, 9α-11α-methanoepoxy-PGF2α, and thromboxane (TX) B2. PGA1, and PGD2 at 30 μM caused morphological deformation of Gin-1 cells. All the PGs tested at 30 μM suppressed the proliferation of Gin-1 cells in the logarithmic growth phase. Furthermore, all the PGs tested at 10 μM suppressed DNA synthesis, collagen synthesis, and noncollagenous protein synthesis in confluent Gin-1 cells, while exerting no effect on GAG synthesis. The concentrations of PGs used are beyond those found in healthy gingiva. However, in periodontitis the local concentrations of some PGs within the gingiva are expected to be extremely elevated beyond the physiological level. These results suggest that PGs may play an important role as a negative regulator in metabolism and some pathologic gingival conditions by suppressing the functions of gingival fibroblasts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1995.tb01280.x
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  • 7
    Electronic Resource
    Electronic Resource
    Simple singularities and topology of symplectically filling 4-manifold (1999)
    Springer
    Commentarii mathematici Helvetici 74 (1999), S. 575-590 
    Details
    ISSN: 1420-8946
    Keywords: Key words. Fillable contact structure, symplectic filling, simple singularity, simply elliptic singularity, the Seiberg-Witten monopole equations.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract. Topological restrictions of symplectically filling 4-manifolds of links around simple singularities are studied by using the Seiberg-Witten monopole equations. In particular, the intersection form of minimal symplectically filling 4-manifolds of the singularity of type E 8 is determined. Moreover, for the case of simply elliptic singularities, similar restrictions are obtained. In the proof, a vanishing theorem of the Seiberg-Witten invariant is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000140050106
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  • 8
    Electronic Resource
    Electronic Resource
    Twists of elliptic curves (1997)
    Springer
    Compositio mathematica 106 (1997), S. 349-360 
    Details
    ISSN: 1570-5846
    Keywords: elliptic curves ; modular forms.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract If E is an elliptic curve over $$\mathbb{Q}$$ , then let E(D) denote theD-quadratic twist of E. It is conjectured that there are infinitely many primesp for which E(p) has rank 0, and that there are infinitely many primes $$\ell $$ for which $$E(\ell )$$ has positive rank. For some special curvesE we show that there is a set S of primes p with density $$\frac{1}{3}$$ for which if $$D = \prod {p_j } $$ is a squarefree integer where $$p_j \in S$$ , then E(D) has rank 0. In particular E(p) has rank 0 for every $$p \in S$$ . As an example let E1 denote the curve $$E_1 :y^2 = x^3 + 44x^2 - 19360x + 1682384$$ . Then its associated set of primes S1 consists of the prime11 and the primes p for which the order of the reduction ofX0(11) modulo p is odd. To obtain the general result we show for primes $$p \in S$$ that the rational factor of L(E(p),1) is nonzero which implies thatE(p) has rank 0. These special values are related to surjective $$\mathbb{Z}/2\mathbb{Z}$$ Galois representations that are attached to modularforms. Another example of this result is given, and we conclude with someremarks regarding the existence of positive rank prime twists via polynomialidentities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1000191408511
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  • 9
    Electronic Resource
    Electronic Resource
    Molecular cloning of feline leukemia provirus genomes integrated in the feline large granular lymphoma cells (1990)
    Springer
    Archives of virology 111 (1990), S. 177-185 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Feline leukemia virus (FeLV) is a horizontally transmitted agent of the domestic cat which is known to be associated with wide spectrum of diseases of the hematopoietic system. In the present study, proviral DNAs of FeLV proviruses were examined in the tumor cells of natural killer cell lineage which is very rare in cats. In the chromosomal DNA of the tumor cells, 5 distinct bands corresponding to exogenous FeLV provirus genomes were detected by digestion withEcoRI which does not cut most FeLV isolates. Five clones of pLC1, pLC2, pLC3, pLC4, and pLC5 obtained from the 5 respective bands were analysed by restriction endonuclease mapping and Southern blot hybridization using gene-specific probes of FeLV. The results have clearly demonstrated that pLC4 and pLC5 contained large deletions in thepol and part ofgag regions, while the full-length proviruses could be observed in pLC1 and pLC2. Furthermore, pLC3 contained part of a variant FeLV genome having anEcoRI site in itsgag region. The molecular clones of defective and variant FeLV in this study may be useful for the further examination of tumorigenesis of large granular lymphoma in the cat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01311052
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  • 10
    Electronic Resource
    Electronic Resource
    A new model of osteopenia using ectopically induced bone: effects of parathyroid hormone and estradiol on bone turnover in induced bone (1993)
    Springer
    Osteoporosis international 3 (1993), S. 128-131 
    Details
    ISSN: 1433-2965
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01621886
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