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  • 2000-2004  (1)
  • 1980-1984  (5)
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  • 1
    Electronic Resource
    Electronic Resource
    In situ pressure–temperature conditions of a tectonic mélange: Constraints from fluid inclusion analysis of syn-mélange veins (2003)
    Melbourne, Australia : Blackwell Science Pty
    The @island arc 12 (2003), S. 0 
    Details
    ISSN: 1440-1738
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Abstract  Pressure and temperature (P–T) conditions of mélange formation are estimated from fluid inclusions within “syn-mélange” veins developed in the necks of boudins of sandstone blocks in the mélange of the Shimanto accretionary complex, south-west Japan. The mélange records décollement-zone processes. P–T conditions are in the range of 81 (+15) to 235 (±18) MPa and 150 (±25) to 220 (±31)°C. Assuming a constant fluid-pressure to lithostatic-pressure ratio for each data set, we estimate a P–T gradient of between 10.0°C/km (+0.2/−1.5) (lithostatic pressure) and 4.2°C/km (+0.1/−0.9) (hydrostatic pressure) from these results. The estimated lithostatic P–T gradient is much lower than that calculated from the age of the subducting oceanic plate. The estimated P–T conditions suggest that the mélange was formed within the seismogenic zone (hypothesized from thermal modeling), although the deformation mechanism of mélange (i.e. dominant diffusive mass transfer mainly in shale matrix with minor brittle breakage mainly in sandstone blocks) does not show evidence of seismic deformation. In addition, at the time of syn-mélange vein formation, a shale matrix of mélange has injected into the vein, which indicates a ductile deformation of shale. A possible explanation for this discrepancy is that the mélange was formed during the interseismic period.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1440-1738.2003.00405.x
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  • 2
    Electronic Resource
    Electronic Resource
    Inhibition of interferon production and antiviral action in mouse cells by 4,5′,8-trimethylpsoralen activated with near ultraviolet light (1980)
    Springer
    Archives of virology 63 (1980), S. 69-74 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The DNA of mammalian cells treated with 4,5′,8-trimethylpsoralen (Trioxsalen) is crosslinked (preventing transcription) only after photoactivation with near ultraviolet light. Suppression of gene action in cocultivated or fused cultures, including both induction and antiviral action of fibroblast interferon, can consequently be limited to pretreated cells, an advantage over actinomycin treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01320762
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  • 3
    Electronic Resource
    Electronic Resource
    Localization of human U1 small nuclear RNA genes to band p36.3 of chromosome 1 by in situ hybridization (1984)
    Springer
    Somatic cell and molecular genetics 10 (1984), S. 307-313 
    Details
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Ul small nuclear RNA (Ul snRNA) is encoded by a large family of genes (30–125 copies/haploid genome) which are transcribed by RNA polymerase II. Ul snRNA is thought to function in gene splicing. Since the Ul genes were found to be 〉20 kb apart by analyzing genomic phage clones, the chromosomal location of Ul genes in the human genome was determined using Southern filter analysis of DNA isolated from human-rodent somatic cell hybrids and by in situ hybridization. Human DNA digested with PvuII and probed with a Ul-specific probe, pD2, show several major hybridizing fragments. Of these, two human PvuII fragments of 1.4 kb and 2.4 kb had unique mobilities compared to mouse fragments. In a study of 19 cell hybrids, the human-specific Ul fragments segregated with the chromosome 1 markers peptidase C and adenylate kinase 2. All other chromosomes showed〉-19% discordancy. An additional 13 karyotyped cell hybrids, analyzed by Southern filter analysis, confirmed the assignment of this class of Ul genes to chromosome 1. Additional digests with MspI and PstI indicated that most Ul genes are located on chromosome 1. To determine if the Ul RNAs are located predominantly at one site or dispersed over chromosome 1, a tritium-labeled Ul probe was hybridized in situ to metaphase chromosomes. The majority of the grains were at band 1p36.3, suggesting that most of the Ul genes are located in this region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01535252
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  • 4
    Electronic Resource
    Electronic Resource
    Chromosomal assignments of human genes for serine proteases trypsin, chymotrypsin B, and elastase (1984)
    Springer
    Somatic cell and molecular genetics 10 (1984), S. 369-376 
    Details
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The genes for the serine proteases trypsin, chymotrypsin B, and elastase were chromosomally assigned in man using cDNA probes that have been isolated from a rat pancreatic cDNA library. DNA from human × rodent somatic cell hybrids was cleaved with BamHI or EcoRI and analyzed by Southern filter hybridization methods for the segregation of the genes for trypsin-1 (TRY1), chymotrypsin B (CTRB), and elastase-1 (ELA1). TRY1 was assigned to human chromosome 7q22→qter, CTRB to chromosome 16, and ELA1 to chromosome 12. Although the three genes are members of the same gene family, they are dispersed over different chromosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01535632
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  • 5
    Electronic Resource
    Electronic Resource
    Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse (1984)
    Springer
    Somatic cell and molecular genetics 10 (1984), S. 377-383 
    Details
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The mouse genes for the serine proteases trypsin (Try-1,chymotrypsin B (Ctrb),and elastase (Ela-1)were chromosomally assigned using Southern blot hybridization of mouse × Chinese hamster cell hybrid DNA. cDNA probes for the three genes were hybridized to cell hybrid DNA cleaved with BamHI or HindIII and the segregation of Try-1, Ctrb,and Ela-1was correlated with the segregation of mouse chromosomes. Try-1is located on chromosome 6, Ctrbis on chromosome 8, and Ela-1is on chromosome 15. The three genes fall into three syntenic groups that are conserved in the mouse and human genomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01535633
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  • 6
    Electronic Resource
    Electronic Resource
    Human parathyroid hormone gene (PTH) is on short arm of chromosome 11 (1983)
    Springer
    Somatic cell and molecular genetics 9 (1983), S. 609-616 
    Details
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The human gene for parathyroid hormone (PTH) was chromosomally mapped using human-rodent hybrids and Southern filter hybridization of cell hybrid DNA. A recombinant DNA probe containing human PTHcDNA insert (pPTHm122) hybridized to a 3.7-kb fragment in human DNA cleaved with the restriction enzyme EcoRI. By correlating the presence of this fragment in somatic cell hybrid DNA with the human chromosomal content of the hybrid cells, the PTHgene was mapped to the short arm of the chromosome 11.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01574261
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