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  • 1
    Electronic Resource
    Electronic Resource
    Consideration on an undulator magnetic structure for polarization control (2002)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 73 (2002), S. 1724-1727 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A magnetic structure composed of electromagnets and permanent magnets is proposed as an undulator to control the polarization state of synchrotron radiation. The horizontal field is produced by the permanent magnets and tuned by moving them along the undulator axis, while the vertical field is produced by the electromagnets and tuned by changing the coil current. The proposed device has two important degrees of freedom. One is that of the periodic length of the electromagnets and the other is that of the relative phase between the vertical and horizontal fields. Thanks to them, the proposed device works as various types of undulator to realize polarization control. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1453503
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  • 2
    Electronic Resource
    Electronic Resource
    Green emission from B2N2CO thin films doped with Tb (2002)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 81 (2002), S. 34-36 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Visible light emission has been obtained at room temperature by photoluminescence (PL) and cathodoluminescence (CL) from Tb-doped B2N2CO thin films prepared by radio-frequency magnetron sputtering. The films were deposited by sputtering TbBn (n=4, 6, 12, 25, and 50) targets in an atmosphere of Ar and N2 gas mixture. The films are uniformly composed of very small particles with particle size of about 20–40 nm, which consist of turbostratic BN phase and amorphous phase. The characteristic PL peaks are observed in the spectral range from 300 to 800 nm, and correspond to the two groups of transitions of Tb3+ ions: 5D3→7FJ (J=6, 5, 3) and 5D4→7FJ (J=6, 5, 4, 3). The strongest PL peak at ∼547.2 nm is about four times greater than the other signals in the investigated range, indicating that the films have strong green light emission. CL intensity is very weakly dependent on the temperature. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1490143
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  • 3
    Electronic Resource
    Electronic Resource
    Reduction of interface-state density in 4H–SiC n-type metal–oxide–semiconductor structures using high-temperature hydrogen annealing (2000)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 76 (2000), S. 1585-1587 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effects of hydrogen annealing on capacitance–voltage (C–V) characteristics and interface-state density (Dit) of 4H–SiC metal–oxide–semiconductor (MOS) structures have been investigated. The Dit was reduced to as low as 1×1011 eV−1 cm−2 at Ec−E=0.6 eV using hydrogen annealing above 800 °C, where Ec−E is the energy level from the conduction-band edge. Secondary ion mass spectroscopy and Dit analysis revealed that Dit decreased with the increase of hydrogen concentration accumulated at the SiO2/4H–SiC interface. The interface states at SiO2/4H–SiC are thought to be originated from the dangling bonds of C atoms as well as Si atoms, because Dit decreases as the hydrogen annealing temperature increases and saturates around 800 °C. This high-temperature hydrogen annealing is useful for accumulation-type SiC metal–oxide–semiconductor field-effect transistors, which have n-type MOS structures to reduce the Dit. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.126103
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  • 4
    Electronic Resource
    Electronic Resource
    Shear modulus and thermal properties of gutta percha for root canal filling (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 31 (2004), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary  The purpose of this investigation was to investigate the rheological properties of four commercially available gutta perchas for root canal filling. The relaxation modulus [Gr(0): instantaneous shear modulus] and specific volume of their materials were examined. In addition, the quantity of heat was also studied by differential scanning calorimeter. In a lower temperature range than the first-order transition temperature (melting point), the Gr(0) values of each material were almost identical. A marked decrease of Gr(0) was observed at the melting point, and the range of the first-order transition temperature at heating was from 42·0 to 60·0 °C. At higher temperatures than the first-order transition temperature of each material, a considerable difference in Gr(0) values was observed. The transition temperatures obtained by the results of the Gr(0), specific volume and quantity of heat agreed with one another. A marked specific volume change was observed at the first-order transition temperature. The technique using melted gutta percha may not be favourable compared with the conventional lateral condensation technique because melted gutta percha undergoes a large amount of shrinkage during setting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.2004.01349.x
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  • 5
    Electronic Resource
    Electronic Resource
    Angiosarcoma of the scalp: absence of vascular endothelial cadherin in primary and metastatic lesions (2001)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 144 (2001), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A 73-year-old man with angiosarcoma of the scalp died about 1 year after disease onset, despite systemic and topical administration of recombinant interleukin-2. Histopathology showed typical changes of endothelial cells with very sparse lymphocytic infiltration into the tumour. An autopsy revealed that the primary site penetrated cranial bone and invaded vertically into the subarachnoid space. Multiple metastases to lung, chest wall, vertebrae and ribs were also found. On immunofluorescence staining, the expression of vascular endothelial cadherin, which is present in normal endothelium, was absent from both primary and metastatic sites. This may have promoted local invasion and metastasis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2001.04032.x
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  • 6
    Electronic Resource
    Electronic Resource
    The importance of serum creatine phosphokinase level in the early diagnosis, and as a prognostic factor, of Vibrio vulnificus infection (2001)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 145 (2001), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Vibrio vulnificus infection causes rapidly progressive skin lesions and sepsis in compromised hosts with liver cirrhosis, and is often fatal. Early diagnosis and rapid treatment are important. Objectives To clarify the characteristics of V. vulnificus infection that distinguish it from other cutaneous and soft-tissue bacterial infections and to confirm that serum creatine phosphokinase (CPK) levels are useful in early diagnosis, and are a prognostic factor for, V. vulnificus infection. Methods We analysed the clinical and laboratory findings (especially serum CPK levels) in eight patients with V. vulnificus infection who were treated at the Saga Medical School Hospital between January 1989 and December 1999. Results All eight patients had liver dysfunction and typical skin manifestations. Six had eaten raw seafood before onset. Seven patients had initial skin manifestations in their legs or feet and eventually died, despite prompt therapy in the intensive care unit. CPK levels of six of these seven patients were already elevated at their initial presentation. Only one patient, with skin manifestations solely on his left hand, showed and maintained a normal CPK level and survived. In 23 patients with cutaneous and soft-tissue infections (10 with necrotizing fasciitis, three with erysipelas, 10 with cellulitis), only three patients with necrotizing fasciitis and streptococcal toxic shock syndrome (STSS) showed CPK elevation. Conclusions A high level of serum CPK in cutaneous or soft-tissue bacterial infection is considered useful for an early diagnosis of V. vulnificus infection and STSS. A history of eating raw seafood, underlying liver disease and multiple lesions suggest a diagnosis of V. vulnificus infection, rather than STSS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2001.04347.x
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  • 7
    Electronic Resource
    Electronic Resource
    Ghrelin-Induced Growth Hormone Release From Isolated Rat Anterior Pituitary Cells Depends on Intracellullar and Extracellular Ca2+ Sources (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of neuroendocrinology 16 (2004), S. 0 
    Details
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ghrelin, a novel growth hormone (GH)-releasing peptide, was isolated from the rat stomach as an endogenous ligand to the growth hormone secretagogues receptor. It is known that ghrelin stimulates the release of GH from the rat anterior pituitary gland, but the intracellular signal cascade in somatotrophs has not yet been clarified. In this study, using an isolated cell perifusion system, we examined whether ghrelin- and growth hormone-releasing hormone (GHRH)-induced GH secretion from rat pituitary cells depends on intra- and extracellular Ca2+ and voltage-gated Ca2+ channels. For this purpose, we first measured ghrelin- or GHRH-stimulated GH concentration following treatment with reduced extracellular Ca2+ and/or thapsigargin, an endoplasmic reticulum Ca2+ ATPase inhibitor. Reductions in the extracellular Ca2+ concentration to 0.25 mM and to 0 mM resulted in decreases in ghrelin-stimulated GH secretion to 81% and 39% and decreases in GHRH-induced GH secretion to 83% and 13%, respectively, compared to the levels in the case of 2.5 mM Ca2+ concentration, suggesting that extracellular Ca2+ is essential for both ghrelin- and GHRH-induced GH secretion. Pretreatment with thapsigargin resulted in a reduction in ghrelin-induced GH secretion to approximately 60% of the control level, but GHRH treatment had not effect on the GH secretion. Moreover, preincubation with thapsigargin and 0 mM extracellular Ca2+ concentration resulted in significant inhibition of GHRH- and ghrelin-induced GH secretion. Subsequently, to determine whether ghrelin-stimulated GH secretion was induced through voltage-gated Ca2+ channels, we measured the ghrelin-stimulated GH concentration following treatment with nifedipine, an L-type Ca2+ channel inhibitor, and found that the amount of GH secretion was reduced to 44% of the control level. Furthermore, by replacement of extracellular Na2+ in the medium with N-methyl-d(–)-glucamine, an impermeable molecule, GH secretion was reduced to 47%. In this study, we demonstrated that the GH-stimulatory effect of ghrelin, unlike that of GHRH, is achieved through both intracellular and extracellular Ca2+ sources and that ghrelin-induced extracellular Ca2+ influx involves an L-type voltage-gated Ca2+ channel and Na+ influx.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2826.2004.01237.x
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  • 8
    Electronic Resource
    Electronic Resource
    Masticatory movement in two cases with unusual alignment of the maxillary canine (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Masticatory function was analysed before and after orthodontic treatment in two cases where tooth alignment remained unusual after treatment. The Sirognathograph Analyzing System® was used to analyse the masticatory function. In both cases, the right maxillary first premolar was located where the maxillary canine is normally positioned. The results of orthodontic treatment were satisfactory both morphologically and aesthetically, and masticatory function was greatly improved. However, some problems remained in the mandibular movement due to the abnormal contact between the mandibular teeth and the maxillary first premolar. These findings support the need for examination of masticatory function when treating patients with an unusual tooth alignment even if the results of orthodontic treatment are both morphologically and aesthetically successful.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.2000.00565.x
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  • 9
    Electronic Resource
    Electronic Resource
    Molecular cloning and characterization of a new Japanese cedar pollen allergen homologous to plant isoflavone reductase family (2002)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Japanese cedar (Cryptomeria japonica) pollen is a major cause of seasonal pollinosis, and more than 10% of Japanese people suffer from this allergic disorder. However, only two major pollen allergens, Cry j 1 and Cry j 2, have been identified and exclusively characterized.Objective The aim of this study was to explore and identify important Japanese cedar pollen allergens other than Cry j 1 or Cry j 2.Methods C. japonica cDNA library was immunoscreened by rabbit antiserum raised against a partially purified cedar pollen allergen fraction. An isolated cDNA clone was inserted into a glutathione S-transferase (GST)-tagged Escherichia coli expression vector to obtain recombinant GST fusion protein. Non-fusion recombinant protein was purified by glutathione Sepharose affinity chromatography in conjunction with factor Xa cleavage of the GST moiety. IgE-binding ability of the recombinant protein was then evaluated by western blot analysis and enzyme-linked immunosorbent assay (ELISA).Results The cDNA encodes 306 amino acids with significant sequence similarity to those of plant isoflavone reductase-like proteins, which include a recently identified birch pollen allergen Bet v 5. Western blot analysis demonstrated that recombinant protein was recognized by cedar pollinosis patient IgE. In contrast to Bet v 5 being reported as a minor allergen, the recombinant protein exhibited 76% IgE binding frequency (19/25) against pollinosis patients.Conclusion Here we identified the third member of Japanese cedar pollen allergen homologous to isoflavone reductase. Its high IgE-binding frequency implicates that the isoflavone reductase homologue might be an additional major pollen allergen in C. japonica.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2002.01405.x
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  • 10
    Electronic Resource
    Electronic Resource
    Association between interleukin-18 gene polymorphism 105A/C and asthma (2003)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 33 (2003), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background IL-18 has been shown to exert anti-allergic or allergy-promoting activities, but the existence of genetic polymorphisms in the coding regions of IL-18 gene has not been demonstrated.Objective The aim of this study was to investigate whether polymorphism is present in the coding regions of the IL-18 gene and, if so, to further analyse the association between polymorphism and asthma in a case–control study.Methods We screened the coding regions of the IL-18 gene for polymorphisms by using PCRsingle-stranded conformation polymorphism and direct sequencing of PCR products, followed by analysis of the association between polymorphism and asthma.Results We identified one polymorphism (105A/C) in the coding regions. The frequency of the 105A allele was significantly higher in asthmatic patients than in controls (P〈0.01; odds ratio (OR)=1.83 (1.37–2.26)). Significant linkage disequilibrium was observed between the 105A/C and −137G/C polymorphisms in the 5′ flanking region of the IL-18 gene (D=0.58, P〈0.0001). However, in asthmatic patients the 105A allele was not associated with either total serum IgE or IL-18 levels.Conclusion The 105A/C polymorphism of the IL-18 gene may be associated with the pathogenesis of asthma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2003.01739.x
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