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  • 1995-1999  (7)
  • 1990-1994  (9)
  • 1985-1989  (3)
  • 1955-1959  (3)
  • 1
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 85 (1986), S. 2671-2683 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: In a crossed molecular beams Ar–O2 time-of-flight scattering experiment individual rotational state-to-state transitions are observed up to values of Δj=18. For the collision energy Ec.m.=97 meV a maximum of excitation is found in the neighborhood of the 1→13 rotational transition. In the total differential cross section fast diffraction oscillations could experimentally be resolved. In addition, a new method is explored for extracting cross section information on specific rotational transitions from measurements of appropriate out-of-plane and in-plane total differential laboratory cross sections only. A preliminary comparison of the experiment with theory indicates a need for substantial corrections in the anisotropy of the most recent Ar–O2 potential by as much as 0.2 A(ring).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 2038-2042 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The characteristics of a molecular beam from a piezoelectric pulsed nozzle source are given and, where appropriate, compared to a continuous beam. These include variation during the pulse in the relative intensity and speed ratio for the gases He, Ar, Ne, and N2. The measurements were made by standard time-of-flight and laser-induced fluorescence techniques. For gas valve pulses of time duration less than 500 μs, there was a single peak during which the gases reached continuum steady flow behavior. Typical speed ratios (parallel temperatures) for the gases He, Ar, Ne, and N2 were 19, 34, 34, and 20 (2.1, 0.7, 0.7, and 1.9 K), respectively. These values are comparable to those from a continuous source with equivalent values of p0d, the product of source pressure and nozzle diameter. The dimer concentrations for Ne and Ar were also measured and found to be 0.4% and 0.7%, respectively. A major problem with the valve was its inability to open fully because of the limited motion of the piezoelectric element.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 70 (1997), S. 529-531 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A bunch length monitor for ultrashort (90 fs to 1 ps) electron bunches using a coherent synchrotron radiation detection techniques has been developed in a collaboration between the Thomas Jefferson National accelerator Facility (Jefferson Lab) and the University of Virginia. The noninvasive, high-resolution, high-sensitivity, low-noise monitor employs a state-of-the-art "bandpass" GaAs Schottky whisker diode operated at room temperature. This letter presents the monitor's performance. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 37 (1999), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: We determined the impacts of irrigated vegetable agriculture on ground water quality in a 29 km2 portion of the Wisconsin central sand plain (WCSP). Vegetable fields cover 22% of the study area and are used for growing potatoes, sweet corn, snap beans, peas, field corn, and soybeans. We found that contaminant plumes from fields underlay about 54% of the area. Plumes were 3 to 〉16 m thick and in places occupied the entire aquifer thickness. Impacted ground water retained the chemical signature observed under fields, and compared with unimpacted ground water, had elevated NO3-N (median 13.7 mg L−1 impacted vs. 0.5 for unimpacted) and Cl (median 23 vs. 2.0 mg L−1) and 1.4 to 2.5 times the Ca, Mg, K, Na, and SO4. NO3-N detections exceeded 10 mg L−1 in 58% of impacted monitoring wells compared with none of the unimpacted wells. Evidence of denitrification was observed, but rarely. Residues of the pesticides alachlor, atrazine, carbofuran, metolachlor, and metribuzin were detected, but usually at summed concentrations of 〈1 μg L−1 outside of fields. The maximum observed sum of pesticide residues was 8 μg L−1. Not all potential pesticide residues were detectable by the analytical method.Agricultural impacts limit the aquifer's value as a source of potable water, because wells are unable to tap unimpacted ground water through much of the area. Results of this study are generally applicable to other humid sandy areas in the north-central United States and elsewhere. Impacts might be more severe elsewhere because the agricultural land use is frequently denser and ground water flowpaths are longer.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract An experimental setup using static-field gel electrophoresis (SFGE) was developed to determine radiation-induced DNA double-strand breaks (DSBs) in CHO-K1 cells after exposure to X-rays or heavy charged particles. The fraction of DNA eluted into the gel matrix depends on the quantity of DSBs introduced. In agreement with a recent report, SFGE and pulsed-field electrophoresis were found to be equally sensitive in DSB detection. With radiolabeled DNA from cell cultures, the absolute amount of DNA migrating out of agarose plugs into the gel was quantified by determining the radioactivity in the gel lane. Alternatively, relative measurements of the amount of DNA released into the gel were achieved with a standardized protocol for both SFGE and a subsequent densitometric scanning of photographic negatives from gels stained with ethidium bromide. After calibration with the radioactive method, the fractions of DNA retained could be calculated directly from the data obtained with the densitometric assay to set up classical dose-effect curves. This procedure was validated for its application with heavy ions using an 500 MeV/u lead beam.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 37 (1998), S. 47-51 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Chinese hamster ovary (CHO) cells and thermoluminescent detectors (TLD-700) were used for physical and biological verification of heavy ion treatment planning. Experiments were performed in a cylindrical water phantom, in some cases with lung and bone equivalent material in front of the target volume. The results confirm the possibility of using thermoluminescent detectors for a quantitative verification of dose distributions. CHO cells can be used at least for qualitative dose verification.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 31 (1992), S. 117-121 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary X- and gamma-irradiation of human erythrocyte membranes (250–1000 Gy) was found to decrease the ratio of weakly to strongly immobilized signal height of membrane-bound maleimide spin label (Mal-6). Subsequent incubation of spin-labeled membranes at ambient temperature (21 °C) induced a progressive increase in this ratio, faster for membranes irradiated with low doses which was hampered by protease inhibitors. These results demonstrate that ionizing radiation stimulates proteolysis of erythrocyte membrane proteins by membrane-associated proteases.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 31 (1992), S. 161-180 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Swift heavy ions when penetrating through matter strip off those electrons having a smaller orbital velocity than the ion velocity. The remaining electrons screen the nuclear charge yielding an effective charge. The effective charge of the ions interacts predominately with the target electrons causing excitation and ionizations of the target atoms. Using the Bethe Bloch formula for the energy loss combined with the Barkas formula for effective charge, the energy loss values as well as unrestricted and restricted linear transfer can be calculated within a few percent of accurancy. From the primary energy loss only a small fraction of 10% or less is transformed into excitation. The major part of the energy loss is used for the ionization of the target atoms and the emission of the corresponding electrons with a high kinetic energy. These electrons form the track around the trajectory of the primary ion in which two thirds of the primary energy is deposited by collisions of primary, secondary and later generations of electrons with the target molecules. In the electron diffusion process the energy is transported from the center of the track into the halo. The radial dose decreases with the square of the radial distance from the center. The diameter of the track is determined by the maximum range of the emitted electrons, i.e. by the maximum energy electrons. All ions having the same velocity i.e. the same specific energy produce electrons of the same energy and therefore tracks of the same diameters independent of the effective charge. But the dose inside the track increases with the square of the effective charge. Track structure models using this continuous dose distributions produce a better agreement with the experiment than models based on microdosimetry. The critical volume as used in microdosimetry is too large compared to the size of the DNA as critical structure inside the biological objects. Track structure models yield better results because the gross-structure of the track i.e. its lateral extension and the thin down toward the end of the track is included in these calculations. In a recent refinement the repair capacity of the cell has been included in a track structure model by using the complete shouldered x-ray survival curve as a template for the local damage produced by the particle tracks. This improved model yields presently the best agreement with the experiment.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The effect of high linear energy transfer (LET) radiation on DNAin vitro, both in protective and non-protective environments was investigated. Two hydroxyl radical scavengers, tris(hydroxymethyl) aminomethane and 2-mercaptoethanol, were compared for their ability to protect SV40 DNA from radiation damage over a wide LET range. At comparable OH scavenging capacities, significant differences were found between these protective agents, indicating that other, radical scavenger-dependent processes affected the extent to which the DNA was protected. In general, a decrease in single-strand breaks (SSBs) relative to double-strand breaks (DSBs) was observed as LET increased. This effect was more pronounced when a radioprotector was present. Comparison of the relative biological efficiency (RBE) of radiation damage as LET increased showed a peak of DSB production in the mid-LET range. These data agree with measurements made by Christensen et al. (1972). An explanation for this increase in DSB production efficiency has been proposed based on the particle track structure of high-LET radiation.Correspondence to: G. Taucher-Scholz
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 38 (1999), S. 229-237 
    ISSN: 1432-2099
    Keywords: Key words Ions ; Tumor therapy ; RBE ; Track structure ; Treatment planning ; Carbon beam
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract  The elevated relative biological effectiveness (RBE) of heavy ions like carbon is the main reason for their use in radiotherapy and is due to the microscopic distribution of dose inside each particle track. High local doses produce lesions that are expected to have a diminished possibility of repair. Thus, RBE depends on track structure and on the biological repair capacity of the tissue that is affected by the irradiation. For tumor treatment planning with heavy ions, the beam quality and the tissue sensitivity have to be taken into account. Using the dependence of radial dose distribution on particle energy and atomic number on the physical side and x-ray dose response for the repair capacity on the biological side, the response to particle irradiation can be calculated in the local effect model (LEM) and used for treatment planning. This article traces the route from electron emission as the basis of track structure to the RBE calculation and the application in treatment planning.
    Type of Medium: Electronic Resource
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