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  • 1995-1999  (2)
  • 1980-1984  (2)
  • 15A48  (2)
  • Therapy  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Computing 30 (1983), S. 157-169 
    ISSN: 1436-5057
    Keywords: 65H10 ; 15A48 ; Iterative parallel processes ; best individualR-orders ; ordered positive decomposition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Für konvergente Folgen {x n,1 },...,{x n,s }, welche über ein System (2) von Ungleichungen miteinander verkoppelt sind, werden die besten individuellenR-Ordnungen τ1,...,τ s bestimmt. Dazu wird gezeigt, daß diese gleich den Spektralradien von bestimmten Matrizen sind, welche aus Exponenten in (2) gebildet werden.
    Notes: Abstract For convergent sequences {x n,1 },...{x n,s } coupled by a system (2) of inequalities the optimal individualR-orders τ1,...,τ s are determined as the spectral radii of certain matrices composed of exponents appearing in (2).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Computing 33 (1984), S. 37-49 
    ISSN: 1436-5057
    Keywords: 65H10 ; 90C30 ; 15A48 ; Iterative processes ; bestR-orders ; cone radius of concave operators ; spectral radii ; partial ordering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Die Berechnung der bestenR-Ordnung von Folgen aus iterativen Näherungsverfahren führt auf die Ermittlung des hier eingeführten Kegelradius bestimmter konkaver Operatoren. Das Hauptergebnis der Arbeit ist die Darstellung des Kegelradius als Infimum der Spektralradien aller den konkaven Operator majorisierenden linearen Operatoren. Diese Charakterisierung ist von numerischem Intersse.
    Notes: Abstract The computation of bestR-orders of sequences produced by iterative methods leads to the determination of the cone radius of certain concave operators. The main result of the paper is the representation of the cone radius as the infimum of spectral radii of all linear operators majorizing the concave operator. This characterization is of numerical interest.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1238
    Keywords: Key words Acute pancreatitis ; Therapy ; Dextran ; Hypertonic ; Colloid ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Ultrahigh-molecular dextran (500000 Da) has been shown to prevent pancreatic necrosis when given 30 min after induction of pancreatitis. This study should clarify the following: (a) are dextrans still effective after prolongation of the therapy-free interval? (b) what is the impact of the molecular weight of the dextrans? and (c) is their effect influenced by the dextran concentration or by the addition of hypertonic saline? Animals and interventions: Acute pancreatitis was induced in 70 male dextran-tolerant Wistar rats using intraductal bile-salt infusion and intravenous hyperstimulation. After 3 h, animals were assigned to one of seven groups (n=10 per group) receiving either Ringer solution or different dextrans (10%) including 70000 Da (DEX-70), 160000 Da (DEX-160), 300000 Da (DEX-300) or 500000 Da (DEX-500). Additional groups included DEX-70 (6%) and DEX-70 (10%) in combination with hypertonic NaCl (7.5%) (HHS-70). Ringer solution was given at 24 ml/kg and all dextrans at 8 ml/kg. Measurements and results: Trypsinogen activation peptides (TAP) were quantified in ascites and acinar necrosis after death or sacrifice at 9 h. As an index of less pathological trypsinogen activation, the mean TAP levels in ascites were significantly lower in DEX-70 and DEX-160 compared to Ringer controls (p〈0.05, t-test). Furthermore, the amount of acinar necrosis was significantly lower in all dextran groups except the HHS-70 in comparison with Ringer controls (p〈0.01, t-test). Finally, mortality was significantly reduced from 60% in Ringer controls to 10 and 0%, respectively, in the groups treated with DEX-70 and DEX-160 (p〈0.03, Fisher‘s Exact test). There was a similar trend in all other groups except the HHS-70. Conclusions: Despite a therapy-free interval of 3 h, dextrans reduce trypsinogen activation, prevent acinar necrosis, and improve survival in necrotizing rodent pancreatitis. The molecular weight and concentration of dextran are of secondary importance for these beneficial effects.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1238
    Keywords: Acute pancreatitis ; Therapy ; Dextran ; Hypertonic ; Colloid ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective Ultrahigh-molecular dextran (500 000 DA) has been shown to prevent pancreatic necrosis when given 30 min after induction of pancreatitis. This study should clarify the following: (a) are dextrans still effective after prolongation of the therapy-free interval? (b) what is the impact of the molecular weight of the dextrans? and (c) is their effect influenced by the dextran concentration or by the addition of hypertonic saline? Animals and interventions Acute pancreatitis was induced in 70 male dextran-tolerant Wistar rats using intraductal bile-salt infusion and intravenous hyperstimulation. After 3 h, animals were assigned to one of seven groups (n=10 per group) receiving either Ringer solution or different dextrans (10%) including 70 000 Da (DEX-70), 160 000 Da (DEX-160), 300 000 Da (DEX-300) or 500 000 Da (DEX-500). Additional groups included DEX-70 (6%) and DEX-70 (10%) in combination with hypertonic NaCl (7.5%) (HHS-70). Ringer solution was given at 24 ml/kg and all dextrans at 8 ml/kg. Measurements and results Trypsinogen activation peptides (TAP) were quantified in ascites and acinar necrosis after death or sacrifice at 9 h. As an index of less pathological trypsinogen activation, the mean TAP levels in ascites were significatly lower in DEX-70 and DEX-160 compared to Ringer controls (p〈0.05,t-test). Furthermore, the amount of acinar necrosis was significantly lower in all dextran groups except the HHS-70 in comparison with Ringer controls (p〈0.01,t-test). Finally, mortality was significantly reduced from 60% in Ringer controls to 10 and 0%, respectively, in the groups treated with DEX-70 and DEX-160 (p〈0.03, Fisher's Exact test). There was a similar trend in all other groups except the HHS-70. Conclusions Despite a therapy-free interval of 3 h, dextrans reduce trypsinogen activation, prevent acinar necrosis, and improve survival in necrotizing rodent pancreatitis. The molecular weight and concentration of dextran are of secondary importance for these beneficial effects.
    Type of Medium: Electronic Resource
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