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  • 1
    Electronic Resource
    Electronic Resource
    Reaction of thiols and disulfides with phosphite radicals. A chain mechanism and RS.cntdot./PO32-.cntdot. equilibrium (1981)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 85 (1981), S. 852-855 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j150607a024
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  • 2
    Electronic Resource
    Electronic Resource
    Phosphite radicals and their reactions. Examples of redox, substitution, and addition reactions (1980)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 84 (1980), S. 2156-2160 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100454a010
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  • 3
    Electronic Resource
    Electronic Resource
    Survey and synthesis of intra- and interspecific variation in stomatal sensitivity to vapour pressure deficit (1999)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 22 (1999), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Responses of stomatal conductance (gs) to increasing vapour pressure deficit (D) generally follow an exponential decrease described equally well by several empirical functions. However, the magnitude of the decrease – the stomatal sensitivity – varies considerably both within and between species. Here we analysed data from a variety of sources employing both porometric and sap flux estimates of gs to evaluate the hypothesis that stomatal sensitivity is proportional to the magnitude of gs at low D (≤ 1 kPa). To test this relationship we used the function gs=gsref–m· lnD where m is the stomatal sensitivity and gsref=gs at D= 1 kPa. Regardless of species or methodology, m was highly correlated with gsref (average r2= 0·75) with a slope of approximately 0·6. We demonstrate that this empirical slope is consistent with the theoretical slope derived from a simple hydraulic model that assumes stomatal regulation of leaf water potential. The theoretical slope is robust to deviations from underlying assumptions and variation in model parameters. The relationships within and among species are close to theoretical predictions, regardless of whether the analysis is based on porometric measurements of gs in relation to leaf-surface D (Ds), or on sap flux-based stomatal conductance of whole trees (GSi), or stand-level stomatal conductance (GS) in relation to D. Thus, individuals, species, and stands with high stomatal conductance at low D show a greater sensitivity to D, as required by the role of stomata in regulating leaf water potential.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.1999.00513.x
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  • 4
    Electronic Resource
    Electronic Resource
    ACOUSTIC-INDUCED EYE MOVEMENTS (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 374 (1981), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1981.tb30910.x
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  • 5
    Electronic Resource
    Electronic Resource
    Telomerase activity distinguishes between neuroblastomas with good and poor prognosis (1999)
    Springer
    Annals of oncology 10 (1999), S. 715-721 
    Details
    ISSN: 1569-8041
    Keywords: neuroblastoma ; prognosis ; telomerase activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Treatment of neuroblastoma has remained a major challenge in pediatric oncology because the assessment of the individual prognosis, particularly in disseminated disease is still obscure. Previous studies have correlated clinical outcome with activity levels of telomerase, a cellular reverse transcriptase which has been detected in the majority of human malignant tumors. Patients and methods: In this blind-trial study, a non-radioactive telomeric repeat amplification protocol (TRAP) with an internal telomerase-assay standard was used on an automated laser fluorescence sequencer for the detection and semiquantitative analysis of telomerase activity (TA) in 67 neuroblastomas of all clinical stages from the German Neuroblastoma Trial and 2 ganglioneuromas. TA levels were correlated with event-free and overall survival rates and established prognostic markers such as MYCN. Results: TA was present in 14 of 69 (20%) samples, including 3 of 22 stage IVS, 8 of 14 stage IV, 1 of 10 stage III, 1 of 7 stage II and 1 of 14 stage I neuroblastomas and 0 of 2 ganglioneuromas. We found a strong statistical correlation between the presence of TA and poor clinical prognosis with regard to all tumor stages. Multivariate analysis revealed TA as an independent prognostic marker. In particular, the analysis of TA in IVS neuroblastomas distinguished two different prognostic groups. Conclusions: Our data suggest that TA is an independent prognostic marker in neuroblastoma which, in combination with other markers such as MYCN, may proof useful in assessing the individual patient's prognosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008333500733
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  • 6
    Electronic Resource
    Electronic Resource
    Remote sensing of mass fluxes of trace gases in the boundary layer (1995)
    Springer
    Applied physics 61 (1995), S. 249-251 
    Details
    ISSN: 1432-0649
    Keywords: 42.68 ; 42.30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The combination of remote sensing methods like Doppler lidar and FTIR offers the possibility to determine mass fluxes of gases remotely. Doppler lidar measures the three-dimensional wind vector in the vicinity of diffuse sources or the velocity of air in a chimney plume if an industrial complex is monitored. FTIR is a multi-component remote sensing method for gas concentrations. The Fourier transformation of an interferogram of a Michelson interferometer within a FTIR system converts the recorded intensity (function of optical path length) to a spectral signal (function of wavenumber). Both information, velocity and concentration, give the mass fluxes of the tracer (gas). A first test was performed at Munich-North power station with FTIR and cw-Doppler lidar. Fluxes of CO2, CO, NO, and HC1 were determined. The results are in good agreement with the fluxes measured by in-situ instruments of the power station. The method can be used to control industrial complexes from an outside observation site.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01082043
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  • 7
    Electronic Resource
    Electronic Resource
    Praseodymium-doped Ti:LiNbO3 waveguides (1999)
    Springer
    Applied physics 68 (1999), S. 321-324 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 42.70; 66.30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: 3 by diffusion doping is investigated by means of secondary neutral mass spectrometry and secondary ion mass spectrometry. The diffusion of praseodymium in LiNbO3 can be described by Fick’s laws of diffusion with a concentration-independent diffusion coefficient and a limited solubility of praseodymium in LiNbO3 increasing exponentially with rising temperature. The diffusion depends on the Li2O content of the LiNbO3 crystal. For LiNbO3 crystals with a nominal slight difference in the congruent composition, the diffusion constants and activation energies for Z-cut LiNbO3 are 3.28×10-5 cm2/s and 2.27 eV, and 1.39×10-5 cm2/s and 2.24 eV, respectively. Titanium-doped waveguides are formed in Pr:LiNbO3 and characterised in relation to waveguide loss and absorption in the visible and near infrared.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050895
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  • 8
    Electronic Resource
    Electronic Resource
    Vitamin D 1980 — Eine Bestandsaufnahme (1981)
    Springer
    Journal of molecular medicine 59 (1981), S. 525-534 
    Details
    ISSN: 1432-1440
    Keywords: Vitamin D metabolism ; Parathyroid hormone ; Vitamin D assay ; Calcium and phosphorus metabolism ; Osteodystrophy ; Vitamin D-Stoffwechsel ; Parathormon ; Vitamin D-Assay ; Calcium- und Phosphatstoffwechsel ; Osteopathie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Vitamin D3 und seine verschiedenen Metaboliten nehmen eine zentrale Stellung in der Regulation des Calcium- und Phosphatstoffwechsels ein. Von herausragender Bedeutung ist das Vitamin D-Hormon 1,25-Dihydroxyvitamin D3, das praktisch ausschließlich in der Niere gebildet wird. Seine Synthese unterliegt verschiedenen hormonellen Einflüssen und ist an die Anwesenheit intakten Nierenparenchyms gebunden. Die multifaktorielle Regulation seiner Bildung macht verständlich, daß verschiedene interne Erkrankungen zu Störungen im Vitamin D-Metabolismus führen. 1,25-Dihydroxyvitamin D3 wirkt nicht nur an den klassischen Organen Darm, Knochen und Niere, sondern vermutlich auch an den Nebenschilddrüsen, der Hypophyse, dem Pankreas sowie der Haut. 24,25-Dihydroxyvitamin D3 — in seiner biologischen Effektivität derzeit allerdings noch unterschiedlich beurteilt — stellt eventuell ein zweites biologisch wichtiges Vitamin D-Hormon dar. — Trotz intensiver Forschung ist bisher weder das volle metabolische Schicksal von Vitamin D3 bekannt, noch sind seine biologischen Funktionen voll verstanden.
    Notes: Summary Vitamin D3 and its various metabolites have a central position in the regulation of the calcium-and phosphorus metabolism. Of special importance is 1,25-dihydroxyvitamin D3, which is almost exclusively synthesized in the kidney. Its production is dependent upon several hormonal stimuli and of course occurs normally only in intact renal tissue. The multifactioral regulation of its formation implies that a variety of diseases could cause disturbances in the metabolism of vitamin D. 1,25-dihydroxyvitamin D3 exerts its biological effects not only at the intestine, bone and kidney, but as well presumably in organs as the parathyroid glands, hypophysis, pancreas and skin. 24,25-dihydroxyvitamin D3 — although its biological value is still in debate — represents possibly a second vitamin D-hormone of importance. Inspite of intensive research work the metabolic fate of vitamin D3 and its full biological significance is not yet entirely understood.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01716452
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  • 9
    Electronic Resource
    Electronic Resource
    Digoxin-quinidine interaction in patients with renal failure (1981)
    Springer
    Journal of molecular medicine 59 (1981), S. 521-522 
    Details
    ISSN: 1432-1440
    Keywords: Digoxin-quinidine interaction ; Renal failure ; Digoxin-Chinidin Interaktion ; Niereninsuffizienz
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden Untersuchungen durchgeführt, um festzustellen, ob Chinidin bei Nierenkranken den gleichen Effekt auf den Digoxinserumspiegel zeigt wie bei Gesunden. Vierzehn von fünfzehn niereninsuffizienten Patienten wiesen einen signifikanten Anstieg des Digoxinspiegels nach viertägiger Chinidinbehandlung auf, was zeigt, daß diese Chinidinwirkung nicht nur durch eine Verminderung der renalen Digoxinclearance hervorgerufen wird. Obwohl neun nicht dialysepflichtige Patienten einen Zusammenhang zwischen Kreatininclearance und Anstieg des Digoxinspiegels aufwiesen, ist anzunehmen, daß der Grad der urämiebedingten Intoxikation für den beobachteten Zusammenhang verantwortlich zu machen ist, da die hämodialysierten Patienten keinen höheren Digoxinanstieg im Serum zeigten als die konservativ behandelten Patienten.
    Notes: Summary Investigations were performed in order to study whether or not quinidine would exert similar effects on the serum digoxin concentration in patients with renal failure as in normal subjects. Fourteen out of fifteen patients showed a significant increase of the serum digoxin level after four days of quindine application. This indicates, that the quinidine effect is not solely caused by a decrease of the renal digoxin clearance, although nine patients, not being hemodialysed, revealed a correlation between their creatinine clearance and the rise of the serum digoxin concentration after quinidine. As however, the patients on hemodialysis did not show higher digoxin levels than those treated conservatively, it is suggested that the degree of the uremic intoxication might be responsible for the observed correlation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01696215
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  • 10
    Electronic Resource
    Electronic Resource
    Lymphozytenfunktionen bei Kindern mit Eisenmangel (1984)
    Springer
    Journal of molecular medicine 62 (1984), S. 1091-1093 
    Details
    ISSN: 1432-1440
    Keywords: Iron deficiency ; Lymphocyte function
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 23 children with mild iron-deficiency anemia, 22 children with latent iron-deficiency, and in 46 healthy controls the3H-thymidine incorporation in blood lymphocytes after stimulation with phytohemagglutinin, concanavalin A, pokeweed mitogen, and serum against thymocytic cells was measured. In 11 of the children with iron-deficiency anemia, in 13 of the children with latent iron-deficiency, and in 20 controls the lymphotoxin secretion after phytohemagglutinin stimulation was also performed. All patients studied were without intercurrent infections and were well nourished. No alteration of the lymphocyte function in the patients was found. The concentrations of immunoglobulins and the components C3 and C4 of complement system were also found to be normal. It is suggested that lymphocyte functions are eventually only altered in more severe states of iron-deficiency anemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01711379
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